Detailed information NTG0239402

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: CGZ53_RS08905
• Genome accession: NZ_CP022435
• Coordinates: 1751222..1753663 (-)
• Length: 813 a.a.
• NCBI ID: WP_100912298.1
• Uniprot ID: -
• Organism: Streptococcus uberis strain NZ01
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1746222..1758663

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CGZ53_RS08890 (CGZ53_08880)	-	1747124..1748956 (-)	1833	WP_233845125.1	YSIRK-type signal peptide-containing protein	-
CGZ53_RS08895 (CGZ53_08885)	groL	1749119..1750747 (-)	1629	WP_046388382.1	chaperonin GroEL	-
CGZ53_RS08900 (CGZ53_08890)	groES	1750793..1751080 (-)	288	WP_015912033.1	co-chaperone GroES	-
CGZ53_RS08905 (CGZ53_08895)	clpC	1751222..1753663 (-)	2442	WP_100912298.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
CGZ53_RS08910 (CGZ53_08900)	-	1753663..1754124 (-)	462	WP_015912035.1	CtsR family transcriptional regulator	-
CGZ53_RS08915 (CGZ53_08905)	-	1754338..1754541 (-)	204	WP_100912299.1	cold-shock protein	-
CGZ53_RS08920 (CGZ53_08910)	-	1754793..1755098 (+)	306	WP_230081161.1	hypothetical protein	-
CGZ53_RS08925 (CGZ53_08915)	-	1755100..1757169 (+)	2070	WP_046388384.1	cation:proton antiporter	-
CGZ53_RS08930 (CGZ53_08920)	-	1757295..1758257 (+)	963	WP_015912039.1	VOC family protein	-

Sequence

Protein

• Length: 813 a.a.
• Molecular weight: 90427.04 Da
• Isoelectric Point: 6.6268

>NTDB_id=239402 CGZ53_RS08905 WP_100912298.1 1751222..1753663(-) (clpC) [Streptococcus uberis strain NZ01]
MTDYSLKMQAIFKQAQYQAARFDSPYLETWHLLLAMVVVNNSLAGLVFNEFENKIALEEYEAAAILAIGKAPNDDIKEFE
YKGQSKTLSHILSFADAIRNVTHANEVGSEHVLFAILLNPDIMATRLLELAGFKIKDDGKGDLKLADLRKAIEIQAAYSK
ETIKAIYELRKPKKAKTGGTFSDMMKPAGTAGELSDYTRDLTEMASQGLLEPVIGREKEITRMVQVLSRKTKNNPVLVGE
AGVGKTALAYGLAQRIVTGEIPYELRDMRVLELDMMSVVAGTRFRGDFEERMNQIIDDIESDGHIILFVDELHTIMGSGS
GIDSTLDAANILKPALSRGTLHMVGATTQEEYQKHIEKDAALSRRFSKVLIEEPSVEDAYKILSGLKKSYESYHNVTISD
QAIKTAVKVAHRYLTSKHLPDSAIDLLDEASATVQSFVKKEAPAFITPIDQAIIKGDFKTVSQLLKASKAKPKKPTPVTE
EDIMSTLSKLSGIPLEKISKADSQKYLNLEKELHKRVIGQEDAVSAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVGKTE
LAKALAELLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQV
LDDGQLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDINHDHSAMEKRILEELKKTYRPEFINRIDEKVVFHS
LSQEDMRQVVAIMVQPLIKNLEEKGITLKMQPSALKYLSEVGYDVEMGARPLRRTIQTEIEDKLSEFILSGQLKTGKTLK
IGMSQGKLKFDMV

Nucleotide

• Length: 2442 bp

>NTDB_id=239402 CGZ53_RS08905 WP_100912298.1 1751222..1753663(-) (clpC) [Streptococcus uberis strain NZ01]
ATGACAGATTATTCACTCAAAATGCAAGCTATTTTTAAACAAGCACAATACCAAGCGGCGCGTTTTGATAGCCCCTATTT
AGAAACTTGGCACCTCTTATTGGCAATGGTTGTTGTTAATAATTCACTAGCTGGCCTTGTTTTTAATGAATTTGAAAATA
AGATTGCCTTGGAAGAATATGAAGCGGCAGCTATCTTAGCCATTGGCAAAGCTCCAAATGATGATATTAAGGAGTTTGAA
TATAAAGGTCAGTCAAAAACACTTTCTCATATTTTGTCCTTTGCTGATGCTATTCGAAATGTTACACATGCCAATGAAGT
AGGATCAGAGCATGTTCTTTTTGCTATCTTATTAAATCCTGATATTATGGCAACTCGTTTGCTAGAATTAGCTGGATTTA
AAATCAAAGATGATGGCAAAGGCGATTTGAAATTGGCTGATTTAAGAAAAGCCATTGAAATTCAAGCTGCTTATAGTAAA
GAAACCATTAAAGCTATCTACGAACTCAGAAAACCCAAAAAAGCCAAAACAGGCGGTACTTTCTCAGATATGATGAAACC
AGCTGGCACTGCGGGAGAATTATCAGATTATACGAGAGATTTGACAGAAATGGCAAGTCAAGGCTTACTTGAGCCTGTTA
TTGGCAGAGAAAAAGAAATCACTCGAATGGTTCAAGTCTTAAGTCGTAAAACGAAAAATAATCCAGTTTTAGTCGGTGAG
GCTGGTGTTGGTAAGACAGCATTGGCCTATGGCTTAGCCCAACGGATTGTGACTGGTGAGATTCCATACGAACTTCGTGA
TATGCGTGTCTTAGAATTAGACATGATGAGTGTGGTGGCAGGTACGCGTTTTCGTGGTGATTTTGAAGAACGCATGAATC
AAATTATTGATGATATTGAAAGTGATGGTCATATCATTCTCTTTGTCGATGAATTACACACTATTATGGGATCTGGCAGT
GGTATTGATAGCACTTTAGATGCTGCAAATATCCTCAAACCAGCTCTCTCAAGAGGAACCCTACATATGGTTGGGGCAAC
TACTCAAGAAGAGTATCAAAAACATATTGAAAAAGATGCCGCTTTATCTCGTCGTTTCTCAAAAGTTTTGATTGAAGAAC
CAAGTGTAGAGGATGCCTACAAGATACTATCAGGGTTGAAAAAATCCTACGAAAGCTATCATAATGTCACCATCTCAGAT
CAAGCTATCAAAACAGCAGTCAAAGTTGCTCATCGCTATTTGACGAGCAAGCACTTACCTGATTCTGCGATTGATTTATT
AGATGAAGCTAGCGCAACGGTTCAAAGTTTCGTCAAAAAAGAGGCGCCAGCCTTCATCACACCAATTGACCAAGCCATCA
TAAAAGGTGATTTTAAAACAGTTAGCCAACTTTTGAAAGCTTCCAAGGCTAAGCCCAAGAAACCAACTCCTGTTACTGAA
GAAGATATCATGTCTACATTAAGTAAATTGTCAGGAATTCCACTGGAAAAAATTAGCAAGGCAGATAGTCAGAAATACCT
TAACCTGGAAAAAGAATTGCATAAGCGTGTTATCGGTCAAGAGGATGCAGTCTCAGCAATTTCAAGAGCTATCAGACGCA
ATCAGTCTGGTATTCGAACAGGTAAACGTCCAATTGGCTCCTTTATGTTCCTTGGACCGACAGGTGTTGGGAAAACAGAA
TTAGCAAAAGCTTTAGCAGAACTCTTATTCGATGATGAATCAGCTCTCATTCGTTTTGATATGTCAGAATACATGGAAAA
ATTCGCTGCTAGCCGTTTAAATGGAGCACCTCCAGGATATGTTGGCTATGACGAGGGCGGTGAGTTGACCGAAAAAGTAC
GTAACAAGCCCTATTCTGTTCTTCTCTTCGATGAAGTTGAAAAAGCCCATCCAGATATCTTTAATGTTTTGTTACAAGTC
TTGGATGATGGACAATTAACGGATTCTCGTGGGCGAAAAGTCGATTTTTCAAATACAATCATTATCATGACAAGTAATTT
AGGTGCTACAGCGCTTCGAGATGATAAAACGGTTGGATTTGGTGCTAAAGATATCAACCATGATCATTCGGCCATGGAAA
AACGCATCTTAGAAGAATTGAAAAAAACCTACCGACCAGAATTTATCAACCGAATTGATGAAAAAGTTGTCTTCCATAGC
TTAAGTCAAGAAGACATGCGACAAGTTGTCGCGATTATGGTTCAACCCTTGATTAAGAACTTGGAAGAAAAAGGGATTAC
CCTCAAAATGCAACCATCTGCATTAAAATATTTGTCTGAAGTCGGTTATGATGTTGAGATGGGGGCAAGGCCACTAAGAC
GAACCATCCAAACAGAAATCGAAGACAAGTTGTCAGAATTCATTTTATCTGGTCAACTTAAAACTGGTAAGACTTTAAAA
ATTGGTATGAGCCAAGGTAAATTAAAATTTGATATGGTCTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (721-801)

• AAA domain (Cdc48 subfamily) (AAA_2) (543-714)

• ATPase family associated with various cellular activities (AAA) (AAA) (236-368)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (104-136)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (19-51)

• AAA lid domain (AAA_lid_9) (375-451)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus mutans UA159	74.816	100	0.749
clpC	Streptococcus thermophilus LMG 18311	71.917	100	0.724
clpC	Streptococcus thermophilus LMD-9	71.795	100	0.723
clpC	Streptococcus pneumoniae TIGR4	65.271	99.877	0.652
clpC	Streptococcus pneumoniae Rx1	65.148	99.877	0.651
clpC	Streptococcus pneumoniae D39	65.148	99.877	0.651
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	50.06	100	0.513
clpC	Bacillus subtilis subsp. subtilis str. 168	43.943	100	0.455