Detailed information NTG0023859

Bioinformatically predicted

Overview

• Name: lqsT
• Type: Regulator
• Locus tag: LPL_RS12265
• Genome accession: NC_006369
• Coordinates: 2761512..2762774 (+)
• Length: 420 a.a.
• NCBI ID: WP_011216388.1
• Uniprot ID: Q5WTU5
• Organism: Legionella pneumophila str. Lens
• Function: repress natural transformation (predicted from homology) Competence regulation

Genomic Context

Location: 2756512..2767774

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LPL_RS12255 (lpl2426)	ceg32	2757400..2760228 (+)	2829	WP_011216386.1	Dot/Icm T4SS effector Ceg32/SidI	-
LPL_RS12260 (lpl2427)	mesI	2760230..2761117 (+)	888	WP_080020749.1	Dot/Icm T4SS effector metaeffector MesI	-
LPL_RS12265 (lpl2428)	lqsT	2761512..2762774 (+)	1263	WP_011216388.1	sensor histidine kinase	Regulator
LPL_RS12270 (lpl2429)	-	2762822..2763517 (-)	696	WP_011216389.1	iron-containing redox enzyme family protein	-
LPL_RS12275 (lpl2430)	sdjA	2763914..2766337 (-)	2424	WP_011216390.1	Dot/Icm T4SS effector SdjA	-
LPL_RS12280 (lpl2431)	dupB	2766408..2767601 (-)	1194	WP_080020750.1	Dot/Icm T4SS effector deubiquitinase DupB/LaiF	-

Sequence

Protein

• Length: 420 a.a.
• Molecular weight: 48598.99 Da
• Isoelectric Point: 7.9744

>NTDB_id=23859 LPL_RS12265 WP_011216388.1 2761512..2762774(+) (lqsT) [Legionella pneumophila str. Lens]
MQRLKNIFTAIYQYLLKETEDASHQITLFGIVMMINYPLFGVFWKLEHFQLTEEFILRITAALLCACLAFNQFWPRQLLK
FLPVFWYIVLLFCLPYFFAYLTLINNGSTLWLMNCVSAIFFLLLVSSVLGALVLLVSGVGLAFFHFYILSNNQFVYIPGT
ISLFSLIVTFIAAIIIGALFARDREITYAGRLSGMRMLAGSIAHDLRTPLASIYLQAELQELIVERLNNPEVQKDLKENL
SKITRGIEMSNQLIRMQLNNIQRDKLDTSTFAIYSIKKLLKASLEEYPFKENQKSLIHLNDKNDFSIWIDEVGFKNMMWN
LLKNSLEYIEETHKGEISIWLEQGWEKENFNYLHIKDTAKGLNHKEYEKIFDFFYSGRKDGTGLGLAYCKLLMQAAGGDI
SCKGKKNEFAHFTLKFPKID

Nucleotide

• Length: 1263 bp

>NTDB_id=23859 LPL_RS12265 WP_011216388.1 2761512..2762774(+) (lqsT) [Legionella pneumophila str. Lens]
ATGCAAAGGTTAAAAAATATATTTACTGCAATTTACCAATATTTATTAAAAGAAACTGAAGATGCAAGCCACCAAATCAC
TTTATTTGGCATCGTCATGATGATTAATTACCCTCTTTTCGGAGTTTTCTGGAAACTGGAGCATTTTCAACTGACAGAAG
AATTTATTTTACGCATCACTGCAGCCCTCCTCTGTGCCTGTTTGGCATTTAATCAATTTTGGCCAAGACAATTATTAAAA
TTTCTACCTGTTTTTTGGTATATAGTTCTTCTCTTTTGTTTACCTTACTTTTTTGCTTATTTGACTCTCATAAACAATGG
CTCAACTCTTTGGCTAATGAATTGCGTATCCGCTATCTTTTTTCTTTTATTAGTCTCCAGTGTGTTGGGAGCTCTTGTAT
TGCTTGTATCAGGTGTTGGACTTGCTTTTTTTCATTTTTATATTTTATCAAATAATCAGTTTGTCTATATCCCAGGAACC
ATATCACTTTTTAGTTTAATTGTTACGTTTATTGCAGCAATAATCATTGGTGCTTTGTTTGCACGAGATAGAGAAATTAC
CTATGCCGGACGTTTATCGGGTATGCGCATGCTGGCTGGAAGTATCGCTCATGATTTAAGAACGCCGCTTGCCAGTATTT
ATTTACAAGCGGAATTACAGGAATTGATTGTCGAAAGATTAAATAATCCAGAAGTTCAAAAGGACCTGAAGGAAAATTTA
AGCAAAATTACTCGCGGTATAGAAATGAGTAATCAATTAATTCGTATGCAATTAAATAATATTCAACGAGACAAATTAGA
TACCAGTACATTTGCGATTTATTCCATCAAAAAATTACTCAAGGCGTCTTTAGAAGAATACCCTTTCAAAGAAAATCAAA
AATCATTGATTCATTTAAATGATAAAAATGATTTTTCCATATGGATTGATGAAGTGGGTTTTAAAAATATGATGTGGAAT
TTGCTAAAAAATAGTCTGGAATATATTGAGGAAACCCATAAAGGCGAAATCTCTATCTGGCTAGAACAAGGATGGGAGAA
AGAGAATTTTAATTACCTCCATATAAAAGATACAGCTAAAGGTTTAAATCATAAAGAATATGAAAAAATATTTGATTTCT
TCTATTCTGGCAGAAAAGATGGAACTGGTTTAGGCTTGGCCTATTGCAAACTTCTGATGCAAGCAGCAGGTGGTGATATT
TCGTGTAAAGGGAAAAAAAATGAATTCGCTCATTTCACTTTAAAATTCCCCAAAATTGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (310-417)

• His Kinase A (phospho-acceptor) domain (HisKA) (198-255)

3D structure

• AlphaFold DB: Q5WTU5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
lqsT	Legionella pneumophila subsp. pneumophila str. Philadelphia 1	99.048	100	0.99