Detailed information NTG0238481

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: CFN60_RS17130
• Genome accession: NZ_CP022341
• Coordinates: 3473143..3474306 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain 157
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3468143..3479306

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CFN60_RS17100 (CFN60_17095)	-	3468408..3468827 (-)	420	WP_014419009.1	TIGR03826 family flagellar region protein	-
CFN60_RS17105 (CFN60_17100)	comFC	3468901..3469590 (-)	690	WP_197538213.1	ComF family protein	Machinery gene
CFN60_RS17110 (CFN60_17105)	-	3469596..3469880 (-)	285	WP_022553866.1	late competence development ComFB family protein	-
CFN60_RS17115 (CFN60_17110)	comFA	3469938..3471323 (-)	1386	WP_022553867.1	DEAD/DEAH box helicase	Machinery gene
CFN60_RS17120 (CFN60_17115)	-	3471431..3472279 (-)	849	WP_003151387.1	DegV family protein	-
CFN60_RS17125 (CFN60_17120)	degU	3472377..3473066 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
CFN60_RS17130 (CFN60_17125)	degS	3473143..3474306 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
CFN60_RS17135 (CFN60_17130)	-	3474529..3475176 (+)	648	WP_007407485.1	YigZ family protein	-
CFN60_RS17140 (CFN60_17135)	-	3475181..3476395 (+)	1215	WP_022553868.1	LCP family protein	-
CFN60_RS17145 (CFN60_17140)	-	3476495..3477571 (-)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
CFN60_RS17150 (CFN60_17145)	tuaH	3477703..3478899 (-)	1197	WP_022553869.1	teichuronic acid biosynthesis protein TuaH	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=238481 CFN60_RS17130 WP_007407484.1 3473143..3474306(-) (degS) [Bacillus velezensis strain 157]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=238481 CFN60_RS17130 WP_007407484.1 3473143..3474306(-) (degS) [Bacillus velezensis strain 157]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTTAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAGCAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTAGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCTGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951