Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   CO646_RS12545 Genome accession   NZ_CP022340
Coordinates   2626796..2628607 (-) Length   603 a.a.
NCBI ID   WP_010734244.1    Uniprot ID   A0A2M9FSJ9
Organism   Enterococcus mundtii strain EMB156     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 2621796..2633607
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CO646_RS12535 abc-f 2622454..2623926 (-) 1473 WP_010734246.1 ribosomal protection-like ABC-F family protein -
  CO646_RS12540 - 2624282..2625322 (-) 1041 WP_096081801.1 zinc-binding dehydrogenase -
  CO646_RS12545 pepF 2626796..2628607 (-) 1812 WP_010734244.1 oligoendopeptidase F Regulator
  CO646_RS12550 - 2628738..2629733 (-) 996 WP_096081802.1 competence protein CoiA -
  CO646_RS12555 - 2629854..2630504 (-) 651 WP_010734242.1 adaptor protein MecA -
  CO646_RS12560 spxA 2630667..2631065 (-) 399 WP_010734241.1 transcriptional regulator SpxA -
  CO646_RS12565 - 2631819..2632541 (+) 723 WP_010734240.1 HAD family hydrolase -

Sequence

Protein


Download         Length: 603 a.a.        Molecular weight: 69036.32 Da        Isoelectric Point: 4.7420

>NTDB_id=238403 CO646_RS12545 WP_010734244.1 2626796..2628607(-) (pepF) [Enterococcus mundtii strain EMB156]
MSETTKLPNREDLPEKLTWDLTPIFSSDQEFDKKYEELTEELKNSEHYKGTLGNGATAFLEALEFVLTMYRKVELIYVYS
HLKNDQDTTNTTYQALYARAGSLLSKVSEAIAWYEPEVLQLSDEQIWQYFEEEPKLEVYRHYVKQMVDNRAHILSADQEA
LLAGAGEIFGASSGTFAVLNNADLEFPTITGENGEKIQLSHGVYGQLLESTNREVREAAFKGLYSVYAQFRNTFASTLGT
HIKGHNFKAKARRYASAREAALSNNHIPESVYDTLVTVVNKHLPLLHRYMELRKRLLNVDTLHMYDLYTPVLGEAPIKFT
YEEAVEKAIESLAPMGEEYLAVVKEAFSNRWIDVVENKGKRSGAYSSGSYDTNPYILMNWHDTLDQLFTLVHEMGHSVHS
YFTRSNQPFVYGDYSIFLAEIASTTNENILTEHLLATEEDPRVRAYVLNHYLDGFKGTIFRQTQFAEFEHFMHQEDAKGT
PLTSEYLSESYGELNAKYYGPAVEKDPEIKDEWARIPHFYYNYYVYQYSTGFSAASALAKKIWEKEPGALDAYLTYLKAG
NSDYPVEVMKKAGVDMTQAAYIEDAMAVFEQRLNELEALVEEL

Nucleotide


Download         Length: 1812 bp        

>NTDB_id=238403 CO646_RS12545 WP_010734244.1 2626796..2628607(-) (pepF) [Enterococcus mundtii strain EMB156]
ATGAGCGAAACAACGAAGTTACCAAATAGAGAAGATTTGCCTGAAAAATTGACATGGGACCTAACACCAATCTTTTCAAG
CGATCAAGAATTTGATAAAAAGTACGAAGAATTGACTGAAGAATTAAAAAATTCTGAGCATTATAAAGGAACATTAGGTA
ATGGAGCAACAGCATTTTTGGAGGCGCTTGAATTTGTCTTAACAATGTATCGTAAAGTTGAGCTTATTTATGTCTATTCC
CATTTAAAAAATGACCAAGATACGACAAATACGACATATCAAGCATTGTATGCTCGTGCTGGAAGTTTACTTTCAAAAGT
GAGTGAAGCAATTGCTTGGTATGAGCCAGAAGTATTGCAACTTTCTGATGAGCAAATTTGGCAATATTTTGAAGAAGAAC
CAAAATTAGAAGTTTATCGTCATTATGTCAAACAAATGGTTGATAACCGCGCACACATCTTGTCAGCAGATCAGGAAGCA
TTACTTGCTGGAGCCGGAGAAATCTTTGGTGCTTCAAGTGGTACATTTGCAGTATTGAATAATGCTGATTTAGAGTTCCC
AACAATCACTGGCGAGAATGGTGAAAAGATCCAATTATCGCATGGTGTATATGGTCAATTATTAGAAAGTACCAATCGTG
AAGTACGTGAAGCGGCGTTCAAAGGACTATACAGCGTATATGCACAATTTAGAAACACTTTTGCTTCCACACTTGGGACG
CATATCAAAGGGCACAACTTTAAAGCCAAAGCACGTCGATACGCTTCTGCCAGAGAAGCTGCACTAAGCAATAACCATAT
TCCTGAAAGTGTGTATGATACTTTAGTTACTGTTGTGAACAAACATTTGCCGTTATTGCATCGATATATGGAACTACGGA
AACGACTATTAAACGTAGATACATTGCATATGTATGATCTGTATACGCCAGTATTAGGTGAAGCACCAATCAAATTTACG
TATGAAGAAGCAGTAGAAAAAGCCATTGAATCACTTGCGCCAATGGGAGAAGAATATCTGGCTGTCGTAAAAGAAGCATT
TTCAAACCGTTGGATCGATGTAGTCGAGAATAAAGGGAAACGCAGTGGCGCTTATTCTTCTGGTAGTTATGATACCAACC
CTTACATTCTGATGAACTGGCATGATACGTTGGATCAACTGTTCACCTTGGTCCATGAAATGGGACATAGTGTCCACAGC
TATTTCACACGTTCGAACCAACCTTTCGTCTATGGTGATTATTCAATCTTTTTAGCCGAGATCGCGTCAACAACAAATGA
AAATATTTTGACCGAACATTTATTAGCGACCGAAGAAGATCCTCGGGTTCGTGCCTATGTCTTGAATCATTATTTAGATG
GTTTTAAAGGAACAATTTTCCGTCAAACACAATTTGCAGAGTTTGAACACTTCATGCATCAAGAAGATGCAAAAGGAACA
CCTTTGACGAGTGAGTACCTAAGTGAAAGCTATGGCGAATTAAATGCTAAGTATTATGGCCCAGCTGTTGAAAAAGATCC
AGAAATCAAAGATGAATGGGCGCGTATCCCACATTTCTACTATAATTATTATGTCTATCAATACTCAACAGGATTTTCTG
CTGCATCTGCTTTAGCGAAGAAAATCTGGGAGAAAGAACCAGGCGCATTAGATGCTTACCTAACGTATCTAAAAGCAGGA
AACAGCGATTATCCAGTAGAAGTAATGAAGAAAGCTGGTGTGGACATGACCCAAGCAGCTTATATTGAAGATGCAATGGC
CGTGTTTGAACAACGATTAAATGAATTAGAAGCATTAGTGGAAGAATTATAG

Domains

Predicted by InterproScan.

Peptidase family M3 (Peptidase_M3)

(207-587)

Oligopeptidase F (Peptidase_M3_N)

(117-186)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2M9FSJ9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

55.556

98.507

0.547

Multiple sequence alignment