Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   CFN13_RS10360 Genome accession   NZ_CP022291
Coordinates   2033426..2034142 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain EDCC5464     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2028426..2039142
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CFN13_RS10330 (CFN13_10325) - 2028733..2029359 (+) 627 WP_000522384.1 nitroreductase family protein -
  CFN13_RS10335 (CFN13_10330) - 2029629..2030414 (+) 786 WP_000867943.1 carbon-nitrogen family hydrolase -
  CFN13_RS14330 (CFN13_10335) - 2031013..2031147 (-) 135 WP_001549197.1 delta-lysin family phenol-soluble modulin -
  CFN13_RS10345 (CFN13_10340) agrB 2031383..2031952 (+) 570 WP_001105713.1 accessory gene regulator AgrB -
  CFN13_RS10350 (CFN13_10345) agrD 2031949..2032089 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  CFN13_RS10355 (CFN13_10350) agrC 2032114..2033407 (+) 1294 Protein_1926 quorum-sensing sensor histidine kinase AgrC -
  CFN13_RS10360 (CFN13_10355) agrA 2033426..2034142 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  CFN13_RS10365 (CFN13_10360) - 2034214..2034321 (+) 108 WP_031789494.1 hypothetical protein -
  CFN13_RS10370 (CFN13_10365) - 2034510..2035469 (-) 960 WP_001253301.1 carbohydrate kinase -
  CFN13_RS10375 (CFN13_10370) - 2035466..2036950 (-) 1485 WP_000141410.1 sucrose-6-phosphate hydrolase -
  CFN13_RS10380 (CFN13_10375) - 2037099..2038049 (-) 951 WP_000790322.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=238111 CFN13_RS10360 WP_000688492.1 2033426..2034142(+) (agrA) [Staphylococcus aureus strain EDCC5464]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=238111 CFN13_RS10360 WP_000688492.1 2033426..2034142(+) (agrA) [Staphylococcus aureus strain EDCC5464]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATCCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCATAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACACGTATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATCGAATCTATAG
ATTCGAAAGAGCGCATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment