Detailed information NTG0238073

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: CFN12_RS14500
• Genome accession: NZ_CP022290
• Coordinates: 2744289..2745176 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain EDCC5458
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2739289..2750176

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CFN12_RS14465 (CFN12_14395)	-	2739308..2739400 (+)	93	WP_010956583.1	hypothetical protein	-
CFN12_RS14470 (CFN12_14400)	-	2739508..2740005 (-)	498	WP_001065268.1	glutathione peroxidase	-
CFN12_RS14475 (CFN12_14405)	-	2740015..2740275 (-)	261	WP_001789910.1	hypothetical protein	-
CFN12_RS14485 (CFN12_14415)	-	2740657..2740770 (-)	114	WP_011447078.1	hypothetical protein	-
CFN12_RS14490 (CFN12_14420)	-	2741429..2743429 (-)	2001	WP_000776751.1	ABC transporter permease	-
CFN12_RS14495 (CFN12_14425)	-	2743426..2744181 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
CFN12_RS14500 (CFN12_14430)	braS	2744289..2745176 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
CFN12_RS14505 (CFN12_14435)	braR	2745187..2745852 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
CFN12_RS14510 (CFN12_14440)	-	2745878..2746078 (-)	201	WP_000604728.1	hypothetical protein	-
CFN12_RS14515 (CFN12_14445)	-	2746276..2747700 (+)	1425	WP_000953744.1	alkaline phosphatase	-
CFN12_RS15225 (CFN12_14450)	-	2747760..2747861 (-)	102	WP_000731972.1	SE2200 family small protein	-
CFN12_RS14525 (CFN12_14455)	-	2747983..2748438 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
CFN12_RS14530 (CFN12_14460)	-	2748683..2749444 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=238073 CFN12_RS14500 WP_000143419.1 2744289..2745176(-) (braS) [Staphylococcus aureus strain EDCC5458]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=238073 CFN12_RS14500 WP_000143419.1 2744289..2745176(-) (braS) [Staphylococcus aureus strain EDCC5458]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997