Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   M6_RS03910 Genome accession   NC_006086
Coordinates   765978..766454 (+) Length   158 a.a.
NCBI ID   WP_002984880.1    Uniprot ID   A0A0H2UU18
Organism   Streptococcus pyogenes MGAS10394     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 760978..771454
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M6_RS03885 (M6_Spy0758) - 761019..761807 (+) 789 WP_021340480.1 Nif3-like dinuclear metal center hexameric protein -
  M6_RS03890 (M6_Spy0759) - 761847..762953 (+) 1107 WP_011184448.1 NAD(P)/FAD-dependent oxidoreductase -
  M6_RS03895 (M6_Spy0760) rfbA 763011..763880 (+) 870 WP_002992970.1 glucose-1-phosphate thymidylyltransferase RfbA -
  M6_RS03900 (M6_Spy0761) - 763880..764473 (+) 594 WP_002990099.1 dTDP-4-dehydrorhamnose 3,5-epimerase family protein -
  M6_RS03905 (M6_Spy0762) rfbB 764717..765757 (+) 1041 WP_002984881.1 dTDP-glucose 4,6-dehydratase -
  M6_RS03910 (M6_Spy0763) mutX 765978..766454 (+) 477 WP_002984880.1 NUDIX hydrolase Machinery gene
  M6_RS03915 (M6_Spy0764) - 766512..767693 (+) 1182 WP_011184449.1 AI-2E family transporter -
  M6_RS03920 (M6_Spy0765) - 767683..768930 (+) 1248 WP_021340481.1 tetratricopeptide repeat protein -
  M6_RS03925 (M6_Spy0766) fbp54 768990..770642 (-) 1653 WP_021340474.1 Rqc2 family fibronectin-binding protein Fbp54 -

Sequence

Protein


Download         Length: 158 a.a.        Molecular weight: 18462.68 Da        Isoelectric Point: 4.3268

>NTDB_id=23783 M6_RS03910 WP_002984880.1 765978..766454(+) (mutX) [Streptococcus pyogenes MGAS10394]
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECARREILEETHLTVTEMAFKGIITFPEFTPGH
DWYTYVFKVTGFEGDLISDEESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY

Nucleotide


Download         Length: 477 bp        

>NTDB_id=23783 M6_RS03910 WP_002984880.1 765978..766454(+) (mutX) [Streptococcus pyogenes MGAS10394]
ATGACTCAATTAGCAACCATTTGTTACATTGATAATGGCGATTCTTTGCTATTATTACACCGCAATAAAAAAGAAAATGA
TGTCCACAAAGGCAAGTGGATTTCAGTTGGAGGTAAGCTCGAGGCTGGTGAGACCCCAGATGAGTGTGCCCGTCGTGAGA
TTTTAGAGGAAACCCATTTGACTGTTACAGAGATGGCCTTTAAAGGAATCATTACTTTTCCAGAATTTACCCCTGGTCAT
GACTGGTATACCTATGTTTTTAAAGTAACAGGATTTGAAGGAGACCTCATTTCAGATGAAGAGTCACGAGAAGGAACCTT
GGAATGGGTACCTTACGATCAAGTGTTGGAAAAGCCAACTTGGGAAGGTGATTATGACATTTTTAAATGGATTTTAGAAG
ACCGTCCTTTTTTCTCTGCCAAATTTACCTATGACCAAAACAACCAACTCATGGATAAATCTGTGACCTTTTATTGA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UU18

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

70.253

100

0.703

Multiple sequence alignment