Detailed information    

insolico Bioinformatically predicted

Overview

Name   rexB   Type   Machinery gene
Locus tag   M6_RS03155 Genome accession   NC_006086
Coordinates   608704..611919 (+) Length   1071 a.a.
NCBI ID   WP_011184367.1    Uniprot ID   Q5XCW7
Organism   Streptococcus pyogenes MGAS10394     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 603704..616919
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M6_RS03130 (M6_Spy0606) - 604948..605325 (+) 378 WP_021340346.1 OsmC family protein -
  M6_RS03135 (M6_Spy0607) - 605318..605704 (+) 387 WP_002990406.1 YbgA family protein -
  M6_RS03140 (M6_Spy0608) - 605777..606853 (+) 1077 WP_011054335.1 FtsX-like permease family protein -
  M6_RS03145 (M6_Spy0609) - 606863..607531 (+) 669 WP_023078151.1 ABC transporter ATP-binding protein -
  M6_RS03150 (M6_Spy0610) - 607636..608553 (-) 918 WP_010922125.1 neutral zinc metallopeptidase -
  M6_RS03155 (M6_Spy0611) rexB 608704..611919 (+) 3216 WP_011184367.1 ATP-dependent nuclease subunit B Machinery gene
  M6_RS03160 (M6_Spy0612) rexA 611916..615548 (+) 3633 WP_023078154.1 helicase-exonuclease AddAB subunit AddA Machinery gene
  M6_RS03165 (M6_Spy0613) - 615688..616500 (+) 813 WP_011528469.1 transporter substrate-binding domain-containing protein -
  M6_RS03170 (M6_Spy0614) rpsU 616641..616817 (+) 177 WP_000048058.1 30S ribosomal protein S21 -

Sequence

Protein


Download         Length: 1071 a.a.        Molecular weight: 124178.04 Da        Isoelectric Point: 6.8336

>NTDB_id=23778 M6_RS03155 WP_011184367.1 608704..611919(+) (rexB) [Streptococcus pyogenes MGAS10394]
MKLIYTEMSYSMTEILVNEARKAADQGYRVFYIAPNSLSFEKEREVLTLLPERGTFSIIVTRFVQMSRYFTVESSPSKQH
LDDTTLAMIFYRALMQLKPEDLPSYGRLQNNSVFIEQLVELYKELKNAQLSVHDLTGLDHPQKQEDLIKIIELAETIMIQ
QDYNQDSPLQSFARAIKLGLLNNQLSKTVVVIDGFSRFSAEEDYLLSLLNNNCQEVITGSYVSQKAYQKSFIKGNIYEAS
LHFLQDLAQKYHIKPVFATSNQVFKPAFSRLTQLFEATHDFSQVDWQLQKNDLDHFSLWQCHHQKEEIEHVAKSIRQKLY
EGYRYKDILVLLGDMDAYQLQIGPIFDKFEIPYYLGKAEPMAAHPLVQFIESLERSQRYNWRREDILNMLKSGLFGCFDD
SDIDRFEEYTQFADIKGFTKFSKPFTINSSRQYPLDFLNEMRQDIVLPLQELFKSQKQLGASLVDKLILFLKKIRLAENM
QGLAQSQLEVEKNEEVWKRFTDILTSFHHIFGQEKLRLSDCLALIKTGMKSAQYRVVPATLDVVTIKSYDLVQPHSKPFV
YAIGLTQSHFPKQIHHSGLLSDQERARINEIRNYRHFDIASAENSKKNHQTALSLFNAATKELVLSVPTVINETFDDLSP
YLKELINFGLPLLDKGKNYLSYDNSDIGNYKALLSQIIAINRQDLIEMSDQDKMFWTVVLRYLRKQLRKQQLELPTSDYR
LSTKSLSKEVIEVCFPKGIPLKLSATALTVFYNNQYNYFLKYVLNLNKTESIHPDSRIHGQYLHRVFERLMKDHTQEPFD
NKLKQAIYHTNQESFFQQVYQDNAEAEYSLAILEDIVRSTAPILQLNQNIKVIDQEKNFHLDMGNEILVHGIIDRIDQLS
DGSLGVVDYKSSANQFDIGTFYNGLSPQLVTYLAALKQIAPHDINQLFGAMYLHLQDPKLDLVTFKQIDNTLVESIYKAL
TYKGIFSEVEKEHLSTGAYQTKNALYSNDELETLLNYNKYLYLKAVKHIKKGHFLINPYTSDGKTVQGDQLKAITRFEAD
LDMAQARRLVTLPAKEKKECFLTLMRKESHL

Nucleotide


Download         Length: 3216 bp        

>NTDB_id=23778 M6_RS03155 WP_011184367.1 608704..611919(+) (rexB) [Streptococcus pyogenes MGAS10394]
ATGAAATTAATTTACACAGAGATGAGTTACTCGATGACAGAGATTTTGGTGAATGAAGCACGAAAAGCTGCTGACCAAGG
TTATCGAGTGTTCTATATTGCTCCAAATTCTCTTTCATTTGAAAAGGAAAGAGAAGTCTTAACCTTATTGCCTGAACGAG
GGACTTTTTCGATAATAGTCACCCGGTTCGTTCAAATGTCAAGGTATTTTACAGTTGAGAGCTCTCCTTCTAAGCAACAT
CTAGATGACACGACTTTGGCTATGATTTTTTATCGGGCCTTGATGCAATTAAAACCAGAAGATTTGCCGAGTTATGGTCG
TTTGCAAAATAATTCGGTTTTTATTGAACAACTAGTTGAGTTATATAAGGAATTAAAAAACGCACAATTAAGCGTACATG
ATTTAACAGGGTTAGACCATCCTCAAAAACAAGAAGATCTTATTAAAATTATTGAGCTTGCAGAGACGATCATGATTCAG
CAAGATTATAATCAAGATAGTCCTCTACAATCTTTTGCAAGAGCAATTAAGTTAGGACTTTTAAATAACCAACTATCAAA
AACAGTTGTTGTTATTGATGGTTTTTCACGTTTTTCAGCTGAAGAGGATTATTTATTATCACTTTTAAATAACAACTGTC
AAGAGGTCATCACTGGCAGTTATGTGAGTCAAAAAGCTTATCAAAAATCTTTTATTAAGGGAAATATCTATGAGGCTAGC
CTTCATTTTTTGCAAGATTTGGCTCAAAAATACCATATCAAGCCGGTATTTGCGACCTCTAATCAAGTGTTTAAACCAGC
CTTTTCACGGCTAACACAATTATTTGAAGCAACTCATGATTTTTCACAAGTAGACTGGCAACTCCAAAAGAATGATCTTG
ATCACTTTAGCCTTTGGCAATGTCATCATCAAAAAGAGGAAATTGAACATGTAGCAAAATCCATTCGGCAAAAGCTATAT
GAAGGTTACCGTTATAAGGATATCTTAGTGTTGCTAGGAGATATGGATGCTTATCAATTACAAATTGGGCCTATCTTTGA
TAAGTTTGAAATCCCCTACTATTTAGGAAAAGCAGAGCCTATGGCTGCCCACCCATTAGTCCAATTTATAGAATCGCTCG
AACGAAGTCAGCGCTATAATTGGCGTCGTGAAGACATTTTAAACATGTTAAAATCAGGACTTTTTGGTTGTTTTGATGAT
AGTGATATTGATCGCTTTGAGGAATATACTCAGTTTGCAGATATTAAAGGGTTTACTAAATTTTCAAAGCCTTTTACCAT
TAACTCTTCTAGGCAGTATCCTCTTGACTTTTTAAATGAAATGAGACAAGACATCGTTTTACCTTTGCAAGAATTGTTTA
AGAGTCAAAAACAACTTGGTGCTTCACTTGTTGACAAATTAATACTTTTTTTAAAAAAGATTAGATTAGCTGAGAATATG
CAAGGTTTAGCACAGTCCCAATTAGAGGTGGAAAAAAACGAAGAAGTTTGGAAAAGGTTTACAGATATTTTGACTTCTTT
TCATCATATCTTTGGCCAAGAAAAATTACGACTATCAGATTGCCTTGCTTTAATCAAAACAGGAATGAAATCAGCTCAGT
ATCGTGTTGTTCCAGCGACATTAGATGTTGTCACCATTAAATCTTATGACCTTGTTCAACCACATTCAAAACCTTTCGTT
TATGCAATTGGTCTAACTCAATCACATTTTCCTAAGCAAATTCACCATTCAGGACTACTTTCTGATCAAGAGCGTGCTAG
AATTAATGAAATAAGAAATTATCGTCATTTTGATATTGCTAGTGCCGAAAATAGTAAAAAAAACCATCAAACTGCGTTAT
CTCTGTTTAATGCTGCCACTAAGGAGTTAGTTCTTAGTGTTCCAACGGTAATCAACGAGACATTCGATGATCTATCTCCT
TATCTTAAAGAATTAATAAACTTTGGGTTACCTCTTTTGGATAAAGGCAAAAACTATCTATCTTATGATAATAGCGATAT
TGGTAACTATAAAGCTCTCTTGTCACAAATTATTGCTATTAACCGACAAGATCTTATAGAAATGTCAGATCAAGATAAGA
TGTTTTGGACTGTTGTCTTACGTTATCTCAGGAAACAGTTAAGAAAGCAACAGCTAGAGTTACCTACTTCAGATTATCGT
TTATCAACAAAGTCTTTGTCTAAAGAAGTTATCGAGGTATGTTTTCCAAAGGGAATCCCTTTAAAGCTATCTGCAACTGC
TTTAACCGTTTTTTATAATAATCAGTACAACTATTTTTTGAAATATGTTTTGAATTTAAACAAAACAGAATCCATTCATC
CAGATTCCAGAATTCATGGTCAATACTTGCATCGTGTCTTTGAGCGGTTAATGAAAGATCACACGCAAGAACCGTTTGAT
AATAAATTAAAACAAGCAATCTACCATACCAATCAAGAAAGTTTTTTTCAGCAGGTTTACCAAGATAATGCCGAGGCTGA
GTACAGTTTAGCTATACTAGAAGATATTGTTAGATCAACAGCACCTATCTTGCAACTTAACCAAAACATAAAGGTCATTG
ATCAAGAAAAGAATTTTCATCTGGATATGGGAAATGAGATATTAGTCCACGGGATCATTGATCGTATTGACCAGCTGAGC
GACGGTAGCTTGGGCGTTGTTGACTATAAATCAAGCGCGAATCAATTTGATATTGGGACTTTTTATAATGGGTTGAGTCC
ACAACTAGTGACTTACCTCGCAGCCTTAAAACAGATCGCACCACACGATATAAACCAATTATTTGGGGCTATGTACCTTC
ATTTGCAAGATCCTAAATTGGATCTAGTAACATTTAAACAAATTGATAACACATTAGTGGAGAGTATCTATAAAGCGTTG
ACCTATAAAGGTATTTTTTCAGAAGTCGAAAAAGAGCATCTATCTACTGGTGCTTACCAAACCAAAAATGCTCTTTATTC
CAATGACGAATTGGAAACACTTTTAAATTATAACAAGTACCTCTATCTTAAAGCTGTTAAACACATTAAAAAGGGACATT
TTTTGATTAATCCTTATACAAGCGATGGTAAGACAGTTCAAGGAGATCAATTAAAAGCCATTACCCGTTTTGAAGCAGAT
CTTGACATGGCACAGGCAAGGCGACTAGTGACTCTCCCTGCTAAGGAGAAAAAAGAGTGCTTTTTAACATTAATGAGAAA
GGAGAGCCACTTGTGA

Domains

Predicted by InterProScan.

PD-(D/E)XK nuclease superfamily (PDDEXK_1)

(743-1020)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5XCW7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  rexB Streptococcus pneumoniae R6

41.155

100

0.413

Multiple sequence alignment