Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   CEH05_RS06635 Genome accession   NZ_CP022106
Coordinates   1323633..1325441 (+) Length   602 a.a.
NCBI ID   WP_014642566.1    Uniprot ID   I0JKJ5
Organism   Halobacillus halophilus strain HL2HP6     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 1318633..1330441
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CEH05_RS06610 (CEH05_06610) - 1319349..1319942 (+) 594 WP_014642561.1 GNAT family N-acetyltransferase -
  CEH05_RS06615 (CEH05_06615) spxA 1320226..1320621 (+) 396 WP_014642562.1 transcriptional regulator SpxA -
  CEH05_RS06620 (CEH05_06620) - 1320668..1321330 (-) 663 WP_014642563.1 TerC family protein -
  CEH05_RS06625 (CEH05_06625) mecA 1321627..1322328 (+) 702 WP_014642564.1 adaptor protein MecA -
  CEH05_RS06630 (CEH05_06630) - 1322424..1323569 (+) 1146 WP_014642565.1 competence protein CoiA -
  CEH05_RS06635 (CEH05_06635) pepF 1323633..1325441 (+) 1809 WP_014642566.1 oligoendopeptidase F Regulator
  CEH05_RS21440 - 1325485..1325661 (-) 177 WP_223254264.1 hypothetical protein -
  CEH05_RS06640 (CEH05_06640) - 1325804..1325992 (-) 189 WP_014642568.1 hypothetical protein -
  CEH05_RS06645 (CEH05_06645) - 1326034..1326885 (-) 852 WP_223254265.1 hypothetical protein -
  CEH05_RS06650 (CEH05_06650) - 1326866..1327420 (-) 555 WP_014642570.1 hypothetical protein -
  CEH05_RS06655 (CEH05_06655) - 1327663..1328553 (-) 891 WP_014642571.1 ClpXP adapter SpxH family protein -
  CEH05_RS06660 (CEH05_06660) - 1328550..1328951 (-) 402 WP_014642572.1 globin -
  CEH05_RS06665 (CEH05_06665) - 1329006..1329587 (-) 582 WP_014642573.1 CYTH domain-containing protein -
  CEH05_RS06670 (CEH05_06670) - 1329701..1330339 (+) 639 WP_014642574.1 GTP pyrophosphokinase family protein -

Sequence

Protein


Download         Length: 602 a.a.        Molecular weight: 69394.93 Da        Isoelectric Point: 4.7067

>NTDB_id=236860 CEH05_RS06635 WP_014642566.1 1323633..1325441(+) (pepF) [Halobacillus halophilus strain HL2HP6]
MAATKQLPKREEVPVEKTWDLEAIFATDEEWYKELKEAEELLPELDQYRGKLGESAEQLYNLLDFQDKISNKIGLLFTYA
HMRKDQDTTNSHYQEMNAKAESLYTKIASAMSFIVPEILALPEGKIKGFIKEYEPLKLYEHTLDEITRRKEHVLSEKEEK
LLAGFSEIGANPSQTFGALNNADLTFPTIKNEEGEEVDLTHGRYVGFLKSDDREVRKSAFEAMYDTFGSFKNTFASTLSG
HVKKNNFNAQVRNYERAREAKLNNNNIPETVYDNLIEAVNERLPLLHRYIELRKEVLGLDEVHMYDIYTPLVKDAEMKVS
YEEAKDLVLKGLEPLGEEYVNTVKEGFENRWIDVEENKGKRSGAYSSGHYGTNPYILMNWQDNVNNLFTLAHELGHSLHS
YYTHANQPYRYGNYSIFVAEVASTCNEALLNDYMLKNTKSEKEQLYLLNNFLEGFRGTVFRQTMFAEFEHEIHMQAQNGE
ALTADKLTEIYYDLNKKYFGDNIVIDDHIGLEWARIPHFYMGYYVYQYATGYAAATALADQILSEGDTAVERYKSFLKAG
SSDYPIEVLKQAGVDMTSKDPILSALDVFEEKLNEMEELLKK

Nucleotide


Download         Length: 1809 bp        

>NTDB_id=236860 CEH05_RS06635 WP_014642566.1 1323633..1325441(+) (pepF) [Halobacillus halophilus strain HL2HP6]
ATGGCTGCAACTAAACAATTACCTAAAAGAGAAGAGGTACCCGTAGAAAAAACATGGGACCTTGAAGCTATTTTTGCTAC
AGACGAAGAGTGGTATAAAGAGCTGAAAGAAGCAGAGGAACTCCTGCCTGAACTGGATCAATACCGTGGAAAACTGGGCG
AATCTGCTGAACAGCTTTACAACCTTCTTGATTTTCAAGATAAAATTTCCAATAAAATTGGCCTGCTTTTTACTTATGCC
CATATGCGCAAAGATCAGGATACAACAAACTCCCATTATCAGGAAATGAATGCCAAAGCGGAAAGCTTATATACAAAGAT
TGCCTCGGCAATGAGCTTTATTGTGCCGGAAATCTTAGCTCTCCCTGAAGGAAAAATTAAAGGATTTATTAAGGAATATG
AACCACTGAAATTGTATGAGCATACGCTTGATGAGATTACACGACGTAAGGAGCATGTTCTTAGTGAGAAGGAAGAAAAA
CTGCTCGCTGGTTTCTCTGAAATAGGAGCCAATCCATCGCAGACATTTGGAGCTTTAAATAATGCGGATCTTACTTTTCC
AACGATCAAGAATGAAGAAGGGGAAGAGGTAGATCTTACTCACGGCCGTTATGTCGGTTTTCTTAAATCCGATGACCGTG
AAGTACGAAAATCCGCGTTTGAAGCGATGTATGATACATTTGGTTCTTTCAAAAATACGTTTGCATCGACATTGAGCGGT
CATGTGAAGAAAAATAATTTTAATGCTCAGGTTAGAAATTACGAACGCGCACGTGAAGCGAAATTAAACAACAATAATAT
TCCGGAAACGGTTTATGATAATTTAATTGAAGCTGTTAATGAACGTCTGCCCCTGCTTCATCGCTATATCGAACTTAGAA
AAGAAGTGCTCGGATTAGATGAAGTTCATATGTACGACATCTACACGCCGCTCGTTAAGGACGCGGAAATGAAAGTGTCT
TATGAGGAAGCCAAAGACCTGGTTCTGAAAGGACTCGAGCCGCTAGGGGAGGAATATGTCAATACCGTGAAGGAAGGCTT
TGAGAACCGCTGGATTGACGTTGAGGAGAACAAAGGGAAGCGAAGCGGAGCTTATTCCTCAGGTCACTACGGAACAAACC
CTTATATATTAATGAATTGGCAGGATAATGTGAATAATTTATTTACACTCGCTCATGAATTGGGACATTCCCTGCACAGC
TATTATACGCATGCGAATCAGCCATACCGTTACGGGAATTATTCCATTTTCGTGGCTGAAGTGGCTTCAACGTGTAATGA
GGCACTATTGAATGATTACATGCTGAAGAATACGAAGAGTGAGAAGGAACAGCTTTATTTATTGAATAACTTCCTGGAAG
GTTTCCGCGGCACGGTATTCAGACAAACGATGTTTGCTGAATTTGAACACGAGATTCATATGCAGGCTCAAAACGGGGAA
GCTTTGACAGCGGATAAGCTCACAGAAATCTACTACGACCTGAATAAGAAATATTTTGGAGACAATATTGTGATTGATGA
TCATATCGGCCTGGAATGGGCTCGTATTCCTCACTTCTATATGGGGTATTATGTTTATCAATACGCTACTGGCTACGCGG
CAGCTACGGCGCTTGCGGATCAGATCCTTTCTGAAGGCGACACAGCAGTTGAACGATATAAGAGTTTCCTTAAAGCAGGA
AGCAGCGACTATCCGATTGAAGTGCTGAAACAGGCAGGTGTGGACATGACTTCTAAAGATCCGATTTTGTCCGCCCTTGA
TGTATTTGAAGAAAAGCTGAATGAAATGGAAGAACTGCTTAAAAAGTAA

Domains

Predicted by InterproScan.

Peptidase family M3 (Peptidase_M3)

(208-586)

Oligopeptidase F (Peptidase_M3_N)

(117-186)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I0JKJ5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

49.83

97.674

0.487

Multiple sequence alignment