Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   CEQ33_RS12335 Genome accession   NZ_CP022093
Coordinates   2434986..2435702 (-) Length   238 a.a.
NCBI ID   WP_002482781.1    Uniprot ID   A0A380HJP0
Organism   Staphylococcus saprophyticus strain FDAARGOS_355     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2429986..2440702
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CEQ33_RS12315 (CEQ33_12345) - 2431051..2431275 (+) 225 WP_002482777.1 sulfurtransferase TusA family protein -
  CEQ33_RS12320 (CEQ33_12350) - 2431421..2432374 (+) 954 WP_011302725.1 LacI family DNA-binding transcriptional regulator -
  CEQ33_RS12325 (CEQ33_12355) - 2432460..2433944 (+) 1485 WP_011302726.1 sucrose-6-phosphate hydrolase -
  CEQ33_RS12330 (CEQ33_12360) - 2433941..2434909 (+) 969 WP_011302727.1 carbohydrate kinase -
  CEQ33_RS12335 (CEQ33_12365) agrA 2434986..2435702 (-) 717 WP_002482781.1 quorum-sensing response regulator AgrA Regulator
  CEQ33_RS12340 (CEQ33_12370) agrC 2435715..2437010 (-) 1296 WP_011302728.1 quorum-sensing sensor histidine kinase AgrC -
  CEQ33_RS12345 (CEQ33_12375) agrD 2437036..2437197 (-) 162 WP_002482783.1 cyclic lactone autoinducer peptide AgrD -
  CEQ33_RS12350 (CEQ33_12380) - 2437200..2437769 (-) 570 WP_011302729.1 accessory gene regulator AgrB -
  CEQ33_RS12355 (CEQ33_12385) - 2438528..2439313 (-) 786 WP_011302730.1 carbon-nitrogen family hydrolase -
  CEQ33_RS12360 (CEQ33_12390) - 2439484..2440113 (-) 630 WP_002482786.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27954.74 Da        Isoelectric Point: 5.0875

>NTDB_id=236626 CEQ33_RS12335 WP_002482781.1 2434986..2435702(-) (agrA) [Staphylococcus saprophyticus strain FDAARGOS_355]
MKIFICEDDERQREHMVSIINNYIMIEEKPMEIEVATADPYDILERSKNLNDIGCYFLDIQLEADINGIKLASEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPDELKSRIIDCLETSESRLKLLSKESSVETIELKRGSNSIYVQYDDVM
FFESSTKSHRLIAHLDNRQIEFYGNLKELDQLDERFFRCHNSFVVNRHNIDSIDSKSRVVYFKNNEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=236626 CEQ33_RS12335 WP_002482781.1 2434986..2435702(-) (agrA) [Staphylococcus saprophyticus strain FDAARGOS_355]
ATGAAAATATTCATTTGTGAAGATGATGAAAGACAACGTGAGCACATGGTTTCTATTATTAATAACTACATCATGATTGA
AGAAAAGCCAATGGAAATCGAAGTTGCCACTGCTGATCCTTATGACATCTTAGAACGCTCTAAGAACCTCAATGATATTG
GGTGTTATTTTTTAGATATTCAGCTTGAAGCTGATATTAATGGTATCAAACTTGCTAGTGAGATTCGTAAACATGATCCT
GTAGGTAATATCATCTTTGTTACAAGTCACAGTGAGTTAACTTACCTAACATTTGTCTATAAGGTAGCCGCGATGGATTT
CATTTTTAAAGATGATCCAGATGAATTAAAATCAAGAATTATTGACTGTCTTGAAACTTCAGAATCAAGATTGAAGCTTC
TTTCAAAAGAAAGTAGTGTTGAAACAATTGAATTAAAACGTGGAAGTAATTCGATTTATGTCCAATATGATGATGTTATG
TTCTTTGAATCATCTACTAAATCGCATCGATTGATTGCACATCTTGATAATCGTCAAATTGAGTTTTATGGCAATTTAAA
AGAATTAGATCAACTTGATGAGCGATTTTTCAGATGTCATAATAGCTTTGTCGTCAATAGACACAATATAGATTCTATTG
ACTCTAAGTCACGTGTTGTCTATTTTAAAAATAATGAACATTGCTATGCATCTGTTAGAAATGTCAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A380HJP0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

85.714

100

0.857

Multiple sequence alignment