Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   CEG11_RS05995 Genome accession   NZ_CP021976
Coordinates   1130661..1131317 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain T20E-257     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1125661..1136317
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CEG11_RS05970 (CEG11_05970) oppF 1126190..1127107 (+) 918 WP_003155037.1 oligopeptide ABC transporter ATP-binding protein OppF -
  CEG11_RS05975 (CEG11_05975) - 1127214..1128401 (+) 1188 WP_003155036.1 putative glycoside hydrolase -
  CEG11_RS05980 (CEG11_05980) - 1128519..1129097 (+) 579 WP_003155035.1 GNAT family N-acetyltransferase -
  CEG11_RS05985 (CEG11_05985) spx 1129276..1129671 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  CEG11_RS05990 (CEG11_05990) - 1129729..1130385 (-) 657 WP_003155033.1 TerC family protein -
  CEG11_RS05995 (CEG11_05995) mecA 1130661..1131317 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  CEG11_RS06000 (CEG11_06000) - 1131468..1132628 (+) 1161 WP_003155030.1 competence protein CoiA family protein -
  CEG11_RS06005 (CEG11_06005) pepF 1132856..1134685 (+) 1830 WP_003155028.1 oligoendopeptidase F Regulator
  CEG11_RS19690 (CEG11_06010) - 1134723..1134890 (-) 168 WP_003155026.1 hypothetical protein -
  CEG11_RS06015 (CEG11_06015) spxH 1135176..1136078 (-) 903 WP_003155024.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=235486 CEG11_RS05995 WP_003155032.1 1130661..1131317(+) (mecA) [Bacillus velezensis strain T20E-257]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=235486 CEG11_RS05995 WP_003155032.1 1130661..1131317(+) (mecA) [Bacillus velezensis strain T20E-257]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGAAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895

Multiple sequence alignment