Detailed information NTG0235419

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: SE071780_RS02975
• Genome accession: NZ_CP021972
• Coordinates: 585253..586290 (+)
• Length: 345 a.a.
• NCBI ID: WP_012679161.1
• Uniprot ID: C0MBZ2
• Organism: Streptococcus equi subsp. equi strain ATCC 39506
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 580253..591290

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SE071780_RS02950 (SE071780_00611)	-	580563..581894 (+)	1332	WP_012679156.1	dipeptidase	-
SE071780_RS02955 (SE071780_00612)	arcC	581912..582862 (+)	951	WP_012679157.1	carbamate kinase	-
SE071780_RS02960 (SE071780_00613)	asnA	583082..584074 (+)	993	WP_012679158.1	aspartate--ammonia ligase	-
SE071780_RS02965 (SE071780_00614)	rsmD	584246..584785 (+)	540	WP_012679159.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
SE071780_RS02970 (SE071780_00615)	coaD	584775..585275 (+)	501	WP_012679160.1	pantetheine-phosphate adenylyltransferase	-
SE071780_RS02975 (SE071780_00616)	sepM	585253..586290 (+)	1038	WP_012679161.1	SepM family pheromone-processing serine protease	Regulator
SE071780_RS02980 (SE071780_00617)	-	586852..587466 (+)	615	WP_012679162.1	YutD family protein	-
SE071780_RS02985 (SE071780_00618)	rlmN	587470..588552 (+)	1083	WP_012679163.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
SE071780_RS02990 (SE071780_00620)	-	589834..590364 (+)	531	WP_012515230.1	Dps family protein	-
SE071780_RS02995 (SE071780_00621)	-	590737..590970 (+)	234	WP_012515231.1	YqgQ family protein	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37438.09 Da
• Isoelectric Point: 9.4223

>NTDB_id=235419 SE071780_RS02975 WP_012679161.1 585253..586290(+) (sepM) [Streptococcus equi subsp. equi strain ATCC 39506]
MKTIKKIKWWLIGFVALLFLLLTLFFPLPYYIEMPGGAYDIRSVLTVNGKEDKEKGAYQFVVVSLSRATLAKLLYAWLTP
FTEISTMEDTTGGYSDADYLRINRFYMETSQNSAVYQALTLAGKEVSFDYKGVYVLDVSKDSSFKGVLHLADTVTGVNGK
TFTTSADLIDYVSHLTLGDEVQVQFTTAGESKTEKGKIIKLKNGKNGIGITLTDHTQVISGDEVDFSTGGVGGPSAGLMF
TLDIYDQINHEDLRKGRVIAGTGTIGKDGKVGDIGGAGLKVAAAAAAGADIFFVPNNPVHKDVKKANPKAISNYEEAKKA
AKRLKTAMKIIPVKTVQDAISYLKK

Nucleotide

• Length: 1038 bp

>NTDB_id=235419 SE071780_RS02975 WP_012679161.1 585253..586290(+) (sepM) [Streptococcus equi subsp. equi strain ATCC 39506]
ATGAAAACAATAAAAAAAATTAAATGGTGGCTGATTGGCTTTGTTGCCTTGCTTTTTCTACTGTTGACACTGTTTTTCCC
CTTGCCTTATTATATTGAAATGCCAGGTGGAGCCTATGATATTCGCTCGGTATTGACTGTCAATGGCAAAGAGGATAAGG
AAAAGGGAGCTTATCAGTTTGTTGTAGTGAGCCTCAGTCGGGCCACCTTGGCTAAATTGCTCTATGCTTGGCTAACGCCT
TTCACTGAGATTAGCACCATGGAAGATACTACTGGTGGCTATAGCGATGCTGACTACCTGCGAATTAATCGCTTTTATAT
GGAAACCTCTCAAAACAGCGCTGTTTATCAGGCCCTTACTCTAGCAGGCAAGGAGGTAAGCTTTGATTATAAGGGTGTTT
ATGTCTTAGACGTCAGCAAGGATTCTAGCTTTAAAGGTGTGCTGCACCTAGCAGATACAGTGACAGGTGTCAATGGTAAA
ACATTTACAACGTCTGCCGATCTGATTGATTATGTTTCTCATTTGACCTTGGGAGATGAGGTGCAGGTACAATTTACAAC
CGCTGGTGAGTCAAAGACTGAAAAAGGAAAGATTATTAAGCTTAAAAACGGTAAAAATGGGATTGGCATTACCCTGACAG
ACCACACACAGGTCATTTCTGGTGATGAGGTCGACTTTAGCACTGGAGGTGTGGGTGGACCAAGTGCAGGCTTGATGTTT
ACTCTTGATATTTATGATCAAATCAATCACGAAGACTTGCGCAAGGGACGTGTGATTGCTGGTACAGGAACCATTGGCAA
GGATGGAAAAGTTGGAGATATTGGCGGGGCGGGCCTAAAGGTGGCTGCCGCCGCCGCTGCTGGTGCTGATATTTTCTTTG
TTCCAAATAATCCTGTGCATAAGGACGTCAAAAAAGCAAATCCTAAGGCTATTAGCAATTACGAGGAGGCTAAAAAAGCA
GCTAAACGACTAAAGACAGCAATGAAAATTATTCCTGTGAAAACCGTTCAAGATGCTATAAGCTACCTTAAAAAATAG

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (233-311)

3D structure

• AlphaFold DB: C0MBZ2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	69.855	100	0.699