Detailed information    

insolico Bioinformatically predicted

Overview

Name   rexA   Type   Machinery gene
Locus tag   SPS_RS06955 Genome accession   NC_004606
Coordinates   1327201..1330830 (-) Length   1209 a.a.
NCBI ID   WP_301182343.1    Uniprot ID   -
Organism   Streptococcus pyogenes SSI-1     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1322201..1335830
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPS_RS06930 (SPs1335) rpoD 1322380..1323489 (-) 1110 WP_011054342.1 RNA polymerase sigma factor RpoD -
  SPS_RS06935 (SPs1336) dnaG 1323498..1325312 (-) 1815 WP_011106831.1 DNA primase -
  SPS_RS06940 (SPs1337) mscL 1325442..1325804 (+) 363 WP_011054340.1 large conductance mechanosensitive channel protein MscL -
  SPS_RS06945 (SPs1338) rpsU 1325932..1326108 (-) 177 WP_000048058.1 30S ribosomal protein S21 -
  SPS_RS06950 - 1326249..1327061 (-) 813 WP_011054339.1 transporter substrate-binding domain-containing protein -
  SPS_RS06955 (SPs1340) rexA 1327201..1330830 (-) 3630 WP_301182343.1 helicase-exonuclease AddAB subunit AddA Machinery gene
  SPS_RS06960 (SPs1341) rexB 1330830..1334045 (-) 3216 WP_011054337.1 ATP-dependent nuclease subunit B Machinery gene
  SPS_RS06965 (SPs1342) - 1334196..1335112 (+) 917 Protein_1351 neutral zinc metallopeptidase -

Sequence

Protein


Download         Length: 1209 a.a.        Molecular weight: 138877.94 Da        Isoelectric Point: 6.5805

>NTDB_id=23513 SPS_RS06955 WP_301182343.1 1327201..1330830(-) (rexA) [Streptococcus pyogenes SSI-1]
MSFAPFLSPEAIKHLQENERYSDQSQKRTAQQIEAIYTSGQNILVSASAGSGKTFVMVERILDKILRGVSIDRLFISTFT
VKAATELRERIENKLYSQIAQTTDFQMKVYLTEQLQSLCQADIGTMDAFAQKVVSRYGYSIGISSQFRIMQDKAEQDVLK
QEVFSKLFSEFMNQKEAPAFRALVKNFSGNCKDTSAFRELVYTCYSFSQSTENPKIWLQENFLSAAKTYQRLEDIPDHDI
ELLLLAMQDTANQLRDVTDMEDYGQLTKAGSRSAKYTKHLTIIEKLSDWVRDFKCLYGKAGLDRLIRDVTDLIPSGNDVT
VSKVKYPVFKTLHQKLKQFRHLETILMYQKDCFPLLEQLQDFVFAFSEAYLAVKIQESAFEFSDIAHFAIKILEENTDIR
QSYQQHYHEVMVDEYQDNNHMQERLLTLLSNGHNRFMVGDIKQSIYRFRQADPQIFNQKFRDYQKKPEQGKVILLKENFR
SQSEVLNVSNAVFSHLMDESVGDVLYDEQHQLIAGSHAQTVPYLDRRAQLLLYNSDKDDGNAPSDSEGISFSEVTIVAKE
IIKLHNDKGVPFEDITLLVSSRTRNDIISHTFNQYGIPIVTDGGQQNYLKSVEVMVMLDTLRTINNPRNDYALVALLRSP
MFAFDEDDLARIALQKDNELDKDCLYDKMQRAVIGRGAHPELIHDTLLGKLNVFLKTLKSWRRYAKLGSLYDLIWKIFND
RFYFDFVASQAKAEQAQANLYALALRANQFEKSGYKGLYRFIKMIDKVLETQNDLADVEVAAPKQAVNLMTIHKSKGLQF
PYVFILNCDKRFSMTDIHKSFILNRQHGIGIKYLADIKGLLGETTLNSVKVSMETLPYQLNKQELRLATLSEQMRLLYVA
MTRAEKKVYFIGKASKSKSQEITDPKKLGKLLPLALREQLLTFQDWLLAIADIFSTEDLYFDVRFIEDSDLTQESVGRLQ
TPQLLNPDDLKDNRQSETIARALDMLEAVSQLNANYEAAIHLPTVRTPSQLKAAYEPLLEPIGVDIIEKSSRSLSDFTLP
HFSKKAKVEASHIGSALHQLMQVLPLSKPINQQTLLDALRGIDSNEEVKTALDLKKIESFFCDTSLGQFFQTYQKHLYRE
APFAILKVDPISQEEYVLRGIIDAYFLFDDHIVLVDYKTDKYKQPIELKKRYQQQLELYAEALTQTYKLPVTKRYLVLMG
GGKPEIVEV

Nucleotide


Download         Length: 3630 bp        

>NTDB_id=23513 SPS_RS06955 WP_301182343.1 1327201..1330830(-) (rexA) [Streptococcus pyogenes SSI-1]
ATTTCTTTTGCCCCATTTTTAAGCCCCGAAGCTATTAAACATTTACAAGAAAACGAAAGGTACAGTGATCAGTCTCAAAA
ACGCACAGCTCAACAAATTGAAGCAATTTATACTAGTGGCCAAAATATACTTGTATCAGCTTCTGCTGGTTCAGGAAAAA
CCTTTGTAATGGTCGAACGCATACTTGATAAAATTTTGAGAGGTGTTTCAATTGATCGGCTTTTTATCTCAACCTTTACT
GTTAAAGCAGCTACAGAACTGCGTGAACGGATTGAAAACAAATTATACTCACAAATTGCTCAAACTACAGATTTTCAAAT
GAAAGTTTATTTAACAGAACAATTGCAATCTCTTTGTCAAGCTGATATTGGTACTATGGATGCTTTTGCACAGAAAGTAG
TAAGTCGCTATGGTTATAGCATTGGCATTTCATCCCAATTTCGTATCATGCAGGATAAAGCAGAACAAGATGTTTTAAAG
CAAGAGGTGTTTAGCAAACTCTTTAGTGAGTTTATGAATCAAAAAGAGGCACCGGCGTTTAGGGCTCTTGTGAAAAATTT
TTCTGGTAACTGTAAAGACACTTCAGCTTTTAGAGAGTTAGTTTATACTTGTTATTCTTTTAGCCAATCGACAGAAAATC
CAAAAATATGGTTGCAAGAAAATTTTCTAAGCGCTGCTAAAACTTACCAAAGACTTGAAGATATCCCGGATCATGATATT
GAACTCTTACTTTTGGCAATGCAAGACACTGCAAATCAGCTAAGAGATGTGACTGATATGGAAGATTATGGGCAGCTGAC
TAAGGCAGGTAGCCGATCTGCTAAATACACTAAACACTTAACGATCATAGAAAAGTTGTCTGATTGGGTGCGTGATTTTA
AATGTTTGTATGGAAAAGCCGGATTGGATCGGTTGATCAGAGATGTGACAGACCTTATACCATCTGGGAATGATGTTACA
GTCTCGAAGGTAAAATACCCTGTTTTTAAGACCTTGCATCAAAAATTAAAACAATTTAGGCATTTAGAAACAATTTTAAT
GTATCAGAAAGACTGTTTTCCCTTATTGGAACAGTTACAAGATTTTGTGTTTGCGTTTTCAGAAGCTTATTTAGCTGTCA
AAATACAAGAAAGTGCTTTTGAATTTTCAGATATTGCACACTTTGCAATCAAAATTTTAGAGGAAAATACGGATATTCGC
CAATCCTATCAGCAACACTATCATGAGGTGATGGTTGATGAATATCAAGATAACAATCATATGCAAGAGCGACTCCTGAC
CTTACTATCGAACGGTCATAATCGCTTTATGGTAGGAGATATCAAACAATCGATCTATCGATTTCGGCAAGCCGATCCTC
AGATTTTTAATCAAAAGTTTAGAGACTATCAAAAAAAACCTGAGCAGGGGAAAGTGATTTTACTCAAAGAAAACTTTCGT
AGCCAATCAGAGGTGTTAAATGTCAGCAATGCTGTTTTTAGTCACTTAATGGACGAATCAGTAGGAGACGTCTTATACGA
TGAGCAACATCAGTTAATAGCAGGTAGTCATGCTCAAACAGTCCCCTATCTAGACCGTCGTGCTCAGTTATTGCTATATA
ATAGCGATAAAGATGATGGCAACGCCCCTTCAGATAGTGAGGGTATTTCATTTAGCGAGGTTACAATTGTTGCCAAAGAA
ATTATTAAGCTTCACAATGATAAGGGTGTCCCTTTTGAAGATATTACGTTACTCGTTTCTTCAAGAACAAGAAATGATAT
CATTTCTCATACATTCAATCAATATGGTATTCCTATAGTAACAGATGGTGGGCAGCAAAACTATCTTAAATCTGTTGAAG
TGATGGTTATGTTAGATACATTACGCACCATTAATAACCCAAGAAATGATTATGCCCTTGTGGCTTTACTGCGCTCACCG
ATGTTTGCCTTTGATGAGGATGATTTAGCAAGAATAGCACTTCAAAAAGACAATGAGCTAGATAAAGATTGCCTATATGA
CAAGATGCAAAGGGCTGTGATTGGAAGAGGTGCTCATCCTGAATTGATTCACGATACCTTGCTTGGCAAGTTAAATGTTT
TTTTAAAGACGTTGAAAAGCTGGCGTCGATACGCTAAGCTAGGGTCGTTGTATGACTTGATTTGGAAAATTTTCAATGAT
CGTTTTTATTTTGATTTTGTAGCTAGTCAAGCAAAAGCAGAACAAGCACAAGCTAATCTATACGCATTAGCTCTACGTGC
TAATCAGTTTGAAAAATCGGGCTATAAAGGGCTATACCGTTTTATTAAAATGATTGATAAGGTACTTGAGACGCAAAATG
ACTTAGCAGATGTGGAAGTGGCTGCTCCTAAACAAGCTGTTAATTTAATGACCATTCACAAGTCTAAAGGTTTACAATTT
CCGTATGTATTTATCCTTAATTGTGACAAGCGCTTCTCAATGACAGATATTCATAAATCATTTATTCTGAATCGGCAGCA
CGGTATCGGTATCAAGTACCTTGCAGATATCAAAGGTTTACTTGGTGAAACAACACTCAATTCTGTTAAAGTAAGCATGG
AAACCTTACCTTATCAATTGAACAAACAAGAGTTGCGCTTAGCAACTTTATCAGAACAAATGCGCTTACTGTATGTTGCT
ATGACACGAGCTGAAAAAAAAGTTTATTTTATTGGTAAAGCTAGTAAGAGCAAAAGTCAAGAAATCACAGATCCTAAAAA
GTTAGGCAAACTTTTGCCGCTGGCTTTACGAGAACAGTTATTGACATTCCAAGATTGGCTATTAGCAATAGCAGATATAT
TTTCAACTGAAGATCTTTATTTTGATGTTCGCTTTATTGAAGATAGTGATTTGACACAAGAGTCAGTCGGACGACTTCAA
ACACCACAGTTATTAAATCCAGATGATCTTAAAGATAATCGTCAATCAGAAACAATTGCACGGGCTTTAGATATGTTAGA
AGCAGTGTCTCAATTGAATGCCAATTATGAAGCAGCTATTCATTTGCCAACAGTTCGAACGCCTAGCCAACTTAAGGCAG
CTTACGAGCCTTTATTAGAACCCATTGGTGTAGATATTATAGAGAAATCTTCTCGATCGCTATCTGATTTTACTTTGCCA
CATTTTTCAAAAAAAGCAAAAGTTGAAGCAAGTCATATTGGATCAGCTCTTCATCAGTTGATGCAGGTGCTCCCTTTGTC
AAAACCGATAAATCAACAAACGCTTTTAGACGCTTTAAGAGGAATTGATAGTAACGAAGAGGTAAAAACAGCTCTTGATC
TCAAAAAAATAGAGTCGTTCTTTTGTGATACAAGCCTAGGCCAATTTTTTCAGACTTACCAAAAACACTTGTATCGAGAA
GCACCATTTGCTATTTTAAAAGTTGACCCTATTAGTCAAGAAGAATATGTCCTACGTGGTATTATAGATGCCTACTTTTT
GTTTGATGATCATATTGTATTAGTGGACTATAAAACAGATAAATACAAGCAGCCCATTGAGTTAAAAAAGCGTTACCAAC
AACAGTTGGAGTTATATGCAGAAGCTCTCACTCAAACGTATAAACTTCCTGTGACTAAGCGCTATCTTGTTTTAATGGGA
GGTGGAAAGCCAGAAATTGTCGAAGTTTAA

Domains

Predicted by InterProScan.

UvrD-like helicase C-terminal domain (UvrD_C)

(473-891)

UvrD/REP helicase N-terminal domain (UvrD-helicase)

(29-463)

PD-(D/E)XK nuclease superfamily (PDDEXK_1)

(1045-1196)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  rexA Streptococcus pneumoniae R6

48.371

100

0.491

Multiple sequence alignment