Detailed information    

insolico Bioinformatically predicted

Overview

Name   irvR   Type   Regulator
Locus tag   SPS_RS04630 Genome accession   NC_004606
Coordinates   880213..881001 (-) Length   262 a.a.
NCBI ID   WP_021340822.1    Uniprot ID   -
Organism   Streptococcus pyogenes SSI-1     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 875213..886001
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPS_RS04615 (SPs0875) - 877707..878327 (-) 621 WP_011054596.1 DUF3862 domain-containing protein -
  SPS_RS04620 (SPs0877) - 878690..879778 (-) 1089 WP_011054595.1 site-specific integrase -
  SPS_RS04625 (SPs0878) - 879898..880203 (-) 306 WP_011106738.1 membrane protein -
  SPS_RS04630 (SPs0879) irvR 880213..881001 (-) 789 WP_021340822.1 LexA family transcriptional regulator Regulator
  SPS_RS10310 - 881373..881519 (+) 147 WP_011054593.1 hypothetical protein -
  SPS_RS04635 (SPs0881) - 881653..882432 (-) 780 WP_011054591.1 hypothetical protein -
  SPS_RS04640 - 882489..882695 (+) 207 WP_011054590.1 hypothetical protein -
  SPS_RS04645 (SPs0882) - 882684..883070 (-) 387 WP_011054589.1 hypothetical protein -
  SPS_RS04650 (SPs0883) - 883144..883383 (+) 240 WP_011054588.1 helix-turn-helix domain-containing protein -
  SPS_RS04660 - 883599..883808 (-) 210 WP_002984292.1 hypothetical protein -
  SPS_RS04665 (SPs0885) - 883959..884198 (-) 240 WP_011054586.1 hypothetical protein -
  SPS_RS04670 (SPs0886) - 884365..884550 (+) 186 WP_011054585.1 helix-turn-helix domain-containing protein -
  SPS_RS04675 (SPs0887) - 884628..884924 (+) 297 WP_011054584.1 MerR family transcriptional regulator -
  SPS_RS10560 - 884921..885055 (+) 135 WP_002995985.1 hypothetical protein -
  SPS_RS04680 (SPs0889) - 885071..885385 (+) 315 WP_011054583.1 helix-turn-helix transcriptional regulator -

Sequence

Protein


Download         Length: 262 a.a.        Molecular weight: 29992.22 Da        Isoelectric Point: 9.0535

>NTDB_id=23499 SPS_RS04630 WP_021340822.1 880213..881001(-) (irvR) [Streptococcus pyogenes SSI-1]
MARGRGKLTPQDEEYKKIISAKINSLLLENNLKQGHLADALEIPRSSFNEYVKGNSLPNPGNVQKIADYFGLMKSDIDPR
FAPRKKNHELKIPTSPLVKKITTTVVELKVPRKQKVLDFATEQLKEQKNKITSIEKKLYEYKVYEKLSAGTGYGYFGDGN
YDTVFYDEELDYDFASWVFGDSMEPTYLNGEVVLIKQTGFDYEGGIYAVEWDGQTYIKKVYREKGGLRLVSLNKKYNDKF
APFSEGPRIIGEIVGNFMPKEY

Nucleotide


Download         Length: 789 bp        

>NTDB_id=23499 SPS_RS04630 WP_021340822.1 880213..881001(-) (irvR) [Streptococcus pyogenes SSI-1]
ATGGCAAGAGGACGAGGGAAATTAACACCTCAAGACGAGGAATACAAAAAGATAATTTCTGCTAAAATTAACAGTTTATT
GCTAGAAAACAATTTAAAACAAGGACATTTAGCTGATGCATTGGAAATTCCACGAAGTAGTTTTAATGAATATGTCAAAG
GAAATTCCTTACCTAATCCTGGTAACGTTCAAAAGATAGCTGATTATTTCGGGTTAATGAAGTCTGATATAGATCCTAGA
TTTGCACCTCGTAAGAAAAATCACGAACTCAAAATCCCTACTTCTCCACTCGTCAAAAAAATAACCACAACAGTTGTAGA
ATTAAAGGTTCCTCGTAAACAAAAAGTTTTAGACTTTGCAACAGAACAATTGAAAGAGCAAAAAAACAAAATTACTTCGA
TAGAGAAAAAACTATATGAATACAAAGTCTATGAGAAACTTTCCGCAGGTACAGGTTATGGATATTTTGGTGATGGGAAC
TATGATACTGTTTTTTACGACGAAGAATTAGATTACGATTTTGCCTCTTGGGTTTTTGGTGATTCTATGGAACCAACTTA
TCTGAATGGTGAGGTTGTGCTTATAAAACAAACTGGCTTTGATTATGAAGGTGGCATCTATGCCGTAGAGTGGGACGGAC
AAACCTATATTAAGAAAGTTTACAGAGAAAAGGGTGGCTTGCGCCTTGTGTCCTTAAATAAAAAATACAATGACAAGTTT
GCTCCTTTTAGTGAAGGCCCTCGTATAATAGGGGAAATTGTCGGTAACTTTATGCCTAAAGAGTACTGA

Domains

Predicted by InterProScan.

Peptidase S24-like (Peptidase_S24)

(168-254)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  irvR Streptococcus mutans UA159

38.158

100

0.443

Multiple sequence alignment