Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   S100761_RS06490 Genome accession   NZ_CP021889
Coordinates   1243510..1244166 (+) Length   218 a.a.
NCBI ID   WP_003232942.1    Uniprot ID   A0AAQ3ENL6
Organism   Bacillus subtilis subsp. subtilis strain SRCM100761     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1238510..1249166
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  S100761_RS06465 (S100761_01276) oppF 1238975..1239892 (+) 918 WP_003239287.1 oligopeptide ABC transporter ATP-binding protein OppF -
  S100761_RS06470 (S100761_01277) yjbB 1239999..1241216 (+) 1218 WP_087614503.1 MFS transporter -
  S100761_RS06475 (S100761_01278) yjbC 1241380..1241958 (+) 579 WP_003224597.1 GNAT family N-acetyltransferase -
  S100761_RS06480 (S100761_01279) spx 1242139..1242534 (+) 396 WP_014476435.1 transcriptional regulator Spx -
  S100761_RS06485 (S100761_01280) yjbE 1242577..1243233 (-) 657 WP_003232944.1 TerC family protein -
  S100761_RS21160 - 1243403..1243543 (+) 141 WP_119122854.1 hypothetical protein -
  S100761_RS06490 (S100761_01281) mecA 1243510..1244166 (+) 657 WP_003232942.1 adaptor protein MecA Regulator
  S100761_RS21165 - 1244161..1244283 (-) 123 WP_021479547.1 hypothetical protein -
  S100761_RS06495 (S100761_01282) coiA 1244327..1245478 (+) 1152 WP_087614504.1 competence protein CoiA Machinery gene
  S100761_RS06500 (S100761_01283) pepF 1245708..1247537 (+) 1830 WP_173401378.1 oligoendopeptidase F -
  S100761_RS06505 (S100761_01284) - 1247575..1247742 (-) 168 WP_003244944.1 hypothetical protein -
  S100761_RS06515 (S100761_01285) spxH 1248057..1248956 (-) 900 WP_003245184.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25762.62 Da        Isoelectric Point: 4.0841

>NTDB_id=234441 S100761_RS06490 WP_003232942.1 1243510..1244166(+) (mecA) [Bacillus subtilis subsp. subtilis strain SRCM100761]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPASEDLDALLDDFQKEEQAVNQEEKEQKLQFVLRFGDFEDVISLSNLNVNGSKTTLYSFENR
YYLYVDFCNMTDEEVENQLSILLEYANESSISIHRLEEYGKLIISEHALETIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=234441 S100761_RS06490 WP_003232942.1 1243510..1244166(+) (mecA) [Bacillus subtilis subsp. subtilis strain SRCM100761]
ATGGAAATTGAAAGAATTAACGAGCATACAGTAAAATTTTATATGTCTTACGGAGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATTTGGTATAACCGTGAGCGCAGTGAAGAACTTTTCTGGGAAGTCATGGATGAAGTTCATGAAGAAGAGGAAT
TCGCTGTGGAAGGCCCACTTTGGATTCAAGTTCAGGCACTGGACAAAGGATTAGAAATCATCGTCACAAAAGCCCAGCTT
TCCAAAGACGGACAAAAGCTCGAACTGCCGATTCCTGAGGATAAAAAGCAAGAACCAGCATCTGAGGATCTTGACGCCTT
GCTGGATGATTTCCAGAAAGAAGAGCAAGCCGTCAATCAGGAAGAGAAGGAGCAAAAGCTTCAATTTGTCTTGCGATTTG
GCGATTTTGAGGATGTTATTTCTCTATCTAATTTGAACGTTAACGGAAGCAAAACGACTTTATATTCGTTTGAGAACCGA
TATTATTTATATGTAGATTTTTGCAATATGACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGCTGGAGTACGCAAA
TGAATCCTCAATCAGCATACACCGTCTTGAAGAGTACGGCAAGCTGATTATTTCAGAGCATGCTCTAGAAACGATAAAAA
AACACTTTGCATCATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

99.083

100

0.991

Multiple sequence alignment