Detailed information NTG0234409

Bioinformatically predicted

Overview

• Name: uvrC
• Type: Machinery gene
• Locus tag: CDV25_RS04580
• Genome accession: NZ_CP021886
• Coordinates: 941387..943216 (+)
• Length: 609 a.a.
• NCBI ID: WP_108910958.1
• Uniprot ID: A0A2U8FE61
• Organism: Helicobacter apodemus strain SCJK1
• Function: integration of short DNA fragment (predicted from homology) DNA binding and uptake

Genomic Context

Location: 936387..948216

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CDV25_RS04570 (CDV25_04545)	-	939400..940863 (-)	1464	WP_108910956.1	FAD-dependent oxidoreductase	-
CDV25_RS10750	-	940863..940988 (-)	126	WP_269149134.1	hypothetical protein	-
CDV25_RS04575 (CDV25_04550)	-	940980..941399 (+)	420	WP_239056425.1	hypothetical protein	-
CDV25_RS04580 (CDV25_04555)	uvrC	941387..943216 (+)	1830	WP_108910958.1	excinuclease ABC subunit UvrC	Machinery gene

Sequence

Protein

• Length: 609 a.a.
• Molecular weight: 71067.84 Da
• Isoelectric Point: 9.8231

>NTDB_id=234409 CDV25_RS04580 WP_108910958.1 941387..943216(+) (uvrC) [Helicobacter apodemus strain SCJK1]
MQPLAPLNEYLLKELKKIPSQSGVYHYFDSEGRLLYVGKARNLKNRIKSYFRFTPKLSVAPNLSPRITQMVSQVATLRYI
LVENEHDALILENSLIKQLKPKYNILLRDDKTYPYLCVDKSQDYPRIVLTRKVMKKTQNIRYFGPYSSGGRDLLDCLYEF
FPLVQKESCIRGKKACLFYQIKRCLAPCEGRVSQEEYAKILEKALECIENPKKILTKLEEKMEFLSQHLRFEEAMILRDR
ILKIQQINPLSSVDFARLEDLDIFALVLEEKRGVLVKFFMRNGRIVSSALQNIKSDYGFEIVEIYKQALIDYYHKDLPLI
PKQILIPYDLGEVKQELENFFSLQLQRKISIHFPKNGEKKRLCNLALQNAKETLRLTTNQEENILRDLKALLGLQNIPYR
IEVFDTSHHRGAQSVGAMIVYEEGFIKKSYRHYTLSGSDEYSQMREMLARRIESFSLDFPPDLWLLDGGSGQINLAKELL
QSVGINIEVIGIAKEKIDFKAHRAKGGARDVLRDERLKEYRLKVSDKRLQFLQKLRDEAHRFAITFHQKQKQKTMYKSKI
LELKGIGKSTQKKLLAYFGDFQSIYQASLEELQKVVDSKKALEIYNLLQ

Nucleotide

• Length: 1830 bp

>NTDB_id=234409 CDV25_RS04580 WP_108910958.1 941387..943216(+) (uvrC) [Helicobacter apodemus strain SCJK1]
ATGCAACCATTAGCACCTTTAAATGAATATCTTTTGAAAGAATTAAAAAAAATCCCCTCACAAAGTGGCGTATATCATTA
TTTTGATAGTGAGGGGAGATTGCTTTATGTCGGAAAAGCTAGGAATTTAAAAAATCGCATTAAAAGCTATTTCCGATTTA
CCCCCAAACTTAGTGTTGCGCCTAATTTAAGCCCAAGAATTACACAAATGGTCTCACAAGTGGCTACATTGCGTTATATT
CTTGTAGAAAATGAACACGATGCACTTATTTTGGAAAACTCTCTTATTAAGCAATTAAAGCCTAAGTATAATATCCTCTT
ACGTGATGATAAAACTTATCCTTATTTATGTGTGGATAAAAGCCAAGATTATCCGCGTATAGTTTTGACGCGTAAAGTAA
TGAAAAAAACACAAAACATTCGTTATTTTGGTCCTTATTCTAGTGGAGGAAGGGATTTGTTAGATTGTCTTTATGAGTTT
TTTCCGCTTGTGCAAAAGGAGAGTTGCATCCGCGGTAAAAAGGCTTGTTTGTTTTATCAAATCAAACGTTGTTTAGCACC
TTGTGAGGGGAGGGTGAGTCAAGAAGAATACGCAAAAATTTTAGAAAAAGCCTTAGAATGTATAGAAAATCCCAAAAAGA
TTCTTACAAAACTAGAAGAAAAAATGGAGTTTTTATCGCAACATTTGCGTTTTGAAGAAGCGATGATTTTACGCGATAGA
ATCCTAAAAATTCAGCAGATTAACCCCCTCTCTAGTGTGGATTTTGCTAGATTGGAGGATTTGGATATTTTTGCGCTTGT
GTTAGAGGAGAAAAGAGGGGTTTTAGTGAAGTTTTTTATGCGTAATGGGAGGATTGTCTCTAGTGCTTTACAAAACATTA
AAAGTGACTATGGATTTGAAATAGTGGAGATTTATAAACAAGCCCTCATTGATTATTACCATAAGGATTTACCCTTAATC
CCCAAACAGATATTAATTCCCTATGATTTAGGCGAGGTCAAGCAGGAATTAGAGAATTTCTTTTCTTTGCAATTGCAAAG
AAAAATTTCTATCCATTTCCCCAAAAATGGAGAGAAAAAAAGGCTTTGTAACCTTGCTTTGCAAAATGCTAAAGAAACTC
TAAGATTAACTACTAACCAAGAAGAAAACATTTTAAGGGATTTGAAAGCATTATTAGGACTGCAAAACATTCCTTATCGG
ATTGAAGTGTTTGATACCTCCCACCATAGGGGTGCTCAAAGTGTCGGGGCTATGATTGTTTATGAAGAGGGTTTTATTAA
AAAATCTTATCGGCATTATACATTAAGCGGAAGTGATGAATACTCCCAAATGCGTGAAATGCTTGCAAGACGCATTGAAT
CTTTTTCCCTAGATTTCCCTCCAGATTTATGGCTTTTAGATGGAGGATCGGGGCAGATAAATTTAGCTAAAGAATTGTTG
CAAAGTGTGGGGATAAATATTGAAGTGATAGGCATTGCTAAAGAAAAAATTGATTTTAAAGCCCATCGTGCTAAGGGTGG
AGCTAGGGATGTATTAAGAGATGAGCGTTTAAAGGAATATCGGCTTAAAGTTAGCGATAAACGTTTGCAATTTTTACAAA
AATTACGGGATGAAGCCCATCGTTTCGCTATTACCTTTCACCAAAAACAAAAACAAAAAACAATGTATAAAAGCAAGATT
TTAGAGTTAAAAGGTATTGGTAAAAGCACACAAAAGAAACTTTTAGCTTATTTTGGAGACTTTCAATCTATTTATCAAGC
AAGTTTGGAGGAATTGCAAAAAGTGGTAGATTCTAAAAAAGCTTTAGAGATTTATAATCTCTTGCAATAA

Domains

Predicted by InterproScan.

• UvrB/uvrC motif (UVR) (212-246)

• UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom) (390-544)

• GIY-YIG catalytic domain (GIY-YIG) (22-104)

3D structure

• AlphaFold DB: A0A2U8FE61

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrC	Helicobacter pylori 26695	53.051	96.88	0.514