Detailed information NTG0234219

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: BB162_RS02875
• Genome accession: NZ_CP021869
• Coordinates: 494003..496264 (-)
• Length: 753 a.a.
• NCBI ID: WP_088197829.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae strain SG-M6
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 489003..501264

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BB162_RS02855 (BB162_02855)	-	489079..489849 (+)	771	WP_001131467.1	DivIVA domain-containing protein	-
BB162_RS02860 (BB162_02860)	ileS	490134..492926 (+)	2793	WP_000768156.1	isoleucine--tRNA ligase	-
BB162_RS02865 (BB162_02865)	-	492996..493298 (-)	303	WP_001237037.1	DUF1827 family protein	-
BB162_RS02870 (BB162_02870)	-	493362..493817 (-)	456	WP_000184290.1	NUDIX hydrolase	-
BB162_RS02875 (BB162_02875)	clpE	494003..496264 (-)	2262	WP_088197829.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
BB162_RS02880 (BB162_02880)	-	496562..496792 (+)	231	WP_000443582.1	DUF1797 family protein	-
BB162_RS02885 (BB162_02885)	-	496933..497625 (+)	693	WP_001011647.1	amino acid ABC transporter permease	-
BB162_RS02890 (BB162_02890)	-	497618..498352 (+)	735	WP_000230129.1	amino acid ABC transporter ATP-binding protein	-
BB162_RS02895 (BB162_02895)	-	498639..500333 (+)	1695	WP_001106849.1	phospho-sugar mutase	-

Sequence

Protein

• Length: 753 a.a.
• Molecular weight: 83805.01 Da
• Isoelectric Point: 5.2771

>NTDB_id=234219 BB162_RS02875 WP_088197829.1 494003..496264(-) (clpE) [Streptococcus agalactiae strain SG-M6]
MLCQNCKLNESTIHLYTNVNGKQKQVDLCQNCYQIIKTDPNNPLFSGLNHVSHAPGGINPFFDDFFGDLNNFRAFNGQDL
PNTPPTQAGGNRGGGNGNGRNNNRNQTATPPQAKGILEEFGINVTEIARHGDIDPVIGRDSEIIRVIEILNRRTKNNPVL
IGEPGVGKTAVVEGLAQKIVDGNVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRQRQDVILFIDEIHEIVG
AGTAGEGSMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQKKYEDYHHVKY
NNDAIEAAAVLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKEIDQRLIEAENLKAQATREEDYERAAYFRDQITK
YKEMQQQKVDDQDTPIITEKTIEHIIEEKTNIPVGDLKEKEQSQLINLADDLKQHVIGQDDAVIKIAKAIRRNRVGLGSP
NRPIGSFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLI
LLDEIEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGSGKTEASVGFGASREGRTNSVLGQLGNFFSPEF
MNRFDGIIEFKALDKENLLNIVDIMLSDVNARLAINGIHLDVTDKVKEKLVDLGYDPKMGARPLRRTIQEHIEDAITDYY
LENPSEKELRAIMTSNGNIIIKSSKKTEESTKG

Nucleotide

• Length: 2262 bp

>NTDB_id=234219 BB162_RS02875 WP_088197829.1 494003..496264(-) (clpE) [Streptococcus agalactiae strain SG-M6]
ATGCTCTGTCAAAACTGCAAACTAAACGAATCAACTATTCATTTGTATACAAATGTTAATGGAAAACAAAAGCAAGTTGA
TCTTTGTCAAAATTGCTACCAAATTATTAAAACTGACCCTAATAATCCACTTTTTTCAGGTTTAAATCATGTTTCACATG
CGCCTGGTGGCATCAATCCTTTCTTTGATGATTTCTTTGGAGATTTAAATAATTTCAGAGCCTTTAATGGCCAAGATTTA
CCAAATACTCCTCCTACACAAGCAGGAGGAAACCGAGGTGGAGGAAACGGTAATGGACGAAATAATAATCGCAACCAAAC
TGCAACTCCTCCTCAAGCCAAAGGGATTCTAGAAGAATTTGGTATCAATGTCACTGAAATAGCCCGCCATGGTGATATTG
ACCCTGTTATTGGACGTGACTCAGAAATTATTCGTGTTATCGAAATCCTTAATCGTCGTACAAAAAATAATCCTGTACTT
ATTGGCGAACCCGGCGTAGGGAAAACTGCCGTTGTTGAAGGACTTGCTCAGAAAATTGTTGATGGTAATGTGCCTCATAA
ACTTCAAGGCAAACAAGTTATTCGTTTGGATGTTGTGAGTCTAGTACAAGGAACGGGCATTCGTGGTCAATTTGAAGAAC
GCATGCAAAAGTTGATGGAAGAAATTCGTCAACGTCAAGATGTTATTCTATTCATAGATGAAATTCACGAAATAGTTGGA
GCTGGTACAGCTGGCGAAGGTAGTATGGATGCAGGTAATATTTTAAAACCTGCCCTTGCACGTGGAGAATTACAACTAGT
AGGTGCCACTACTCTCAATGAATATCGTATTATCGAAAAGGACGCTGCCTTAGAACGCCGTATGCAACCTGTAAAAGTCG
ATGAACCTTCTGTTGAAGAAACCATTACTATTTTGAAAGGTATCCAAAAAAAATACGAAGATTATCATCACGTAAAATAT
AATAATGATGCCATAGAAGCAGCTGCAGTACTATCTAATCGTTATATCCAAGACCGCTTTTTACCTGATAAAGCAATAGA
CTTATTAGATGAAGCTGGTTCTAAAATGAACCTAACACTAAATTTTGTTGATCCAAAAGAAATTGATCAACGTCTCATTG
AAGCAGAAAATTTAAAAGCGCAAGCGACTCGTGAAGAAGATTACGAACGTGCAGCTTACTTCCGTGACCAGATTACAAAA
TATAAAGAAATGCAGCAACAAAAGGTCGACGATCAAGATACACCTATTATTACCGAAAAAACAATTGAGCACATCATTGA
AGAAAAAACGAATATCCCTGTTGGTGATTTAAAAGAAAAAGAACAATCTCAATTAATTAATCTCGCAGATGACTTGAAAC
AGCATGTGATCGGCCAGGATGACGCTGTCATTAAGATTGCAAAAGCTATTCGTCGTAATCGAGTTGGTCTTGGTAGCCCA
AACCGTCCTATTGGTTCCTTTTTATTTGTAGGACCAACCGGTGTTGGTAAAACTGAACTTTCTAAACAACTAGCAATTGA
GCTCTTTGGTTCAGCTGATAGTATGATTCGTTTTGATATGTCAGAGTACATGGAAAAGCATGCTGTTGCTAAATTAGTCG
GAGCGCCTCCAGGATACGTGGGATACGAGGAAGCTGGACAACTAACTGAAAAGGTTCGTCGAAATCCTTACTCGCTCATC
CTTCTAGATGAAATTGAAAAAGCTCATCCCGATGTCATGCATATGTTCTTGCAGGTCCTTGATGACGGTCGATTAACAGA
TGGACAAGGAAGAACTGTTAGTTTTAAAGATACCATTATCATCATGACCTCAAATGCTGGTTCTGGTAAAACTGAAGCAA
GTGTTGGCTTTGGTGCCTCACGAGAAGGTAGGACGAATTCCGTACTAGGTCAACTAGGTAACTTCTTCAGCCCTGAATTT
ATGAACCGCTTTGACGGTATTATTGAATTCAAGGCTTTAGATAAAGAGAATCTCCTCAATATCGTTGATATTATGTTATC
TGACGTTAATGCACGTCTCGCCATCAATGGTATTCATCTAGATGTCACTGATAAAGTGAAAGAAAAATTGGTTGATTTAG
GTTACGATCCCAAAATGGGAGCACGTCCATTACGTCGTACCATTCAAGAACATATTGAAGATGCTATCACAGATTACTAT
CTTGAGAATCCAAGCGAAAAAGAACTTCGTGCTATTATGACTAGCAATGGAAATATCATAATAAAATCTTCTAAAAAAAC
TGAGGAAAGTACAAAAGGTTGA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (482-645)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (653-727)

• AAA lid domain (AAA_lid_9) (297-394)

• ATPase family associated with various cellular activities (AAA) (AAA) (159-276)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	85.676	100	0.858
clpE	Streptococcus pneumoniae Rx1	85.314	99.469	0.849
clpE	Streptococcus pneumoniae D39	85.314	99.469	0.849
clpE	Streptococcus pneumoniae R6	85.314	99.469	0.849
clpE	Streptococcus pneumoniae TIGR4	85.18	99.469	0.847
clpC	Lactococcus lactis subsp. cremoris KW2	74.867	99.867	0.748
clpC	Bacillus subtilis subsp. subtilis str. 168	51.18	90.04	0.461
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	47.528	83.267	0.396
clpC	Streptococcus pneumoniae Rx1	46.082	84.728	0.39
clpC	Streptococcus pneumoniae D39	46.082	84.728	0.39
clpC	Streptococcus pneumoniae TIGR4	45.925	84.728	0.389
clpC	Streptococcus mutans UA159	47.03	82.736	0.389
clpC	Streptococcus thermophilus LMD-9	46.276	83.798	0.388
clpC	Streptococcus thermophilus LMG 18311	45.959	83.798	0.385