Detailed information NTG0234119

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: BB164_RS03265
• Genome accession: NZ_CP021867
• Coordinates: 537379..538452 (+)
• Length: 357 a.a.
• NCBI ID: WP_000796095.1
• Uniprot ID: A0A0E1EG10
• Organism: Streptococcus agalactiae strain SG-M25
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 532379..543452

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BB164_RS03235 (BB164_03235)	-	533272..534336 (+)	1065	WP_000021302.1	MmcQ/YjbR family DNA-binding protein	-
BB164_RS03240 (BB164_03240)	asnA	534450..535442 (+)	993	WP_000748011.1	aspartate--ammonia ligase	-
BB164_RS03245 (BB164_03245)	-	535487..535936 (-)	450	WP_000592263.1	thiol reductase thioredoxin	-
BB164_RS03250 (BB164_03250)	rsmD	536066..536605 (+)	540	WP_001266829.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
BB164_RS03255 (BB164_03255)	-	536617..536907 (+)	291	WP_000384889.1	hypothetical protein	-
BB164_RS03260 (BB164_03260)	coaD	536904..537389 (+)	486	WP_000161892.1	pantetheine-phosphate adenylyltransferase	-
BB164_RS03265 (BB164_03265)	sepM	537379..538452 (+)	1074	WP_000796095.1	SepM family pheromone-processing serine protease	Regulator
BB164_RS03270 (BB164_03270)	-	538527..539859 (+)	1333	Protein_554	bifunctional metallophosphatase/5'-nucleotidase	-
BB164_RS03275 (BB164_03275)	-	539928..540506 (+)	579	WP_001224500.1	YutD family protein	-
BB164_RS03280 (BB164_03280)	rlmN	540557..541663 (+)	1107	WP_001124990.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
BB164_RS03285 (BB164_03285)	-	541663..542178 (+)	516	WP_000919802.1	VanZ family protein	-

Sequence

Protein

• Length: 357 a.a.
• Molecular weight: 39199.43 Da
• Isoelectric Point: 10.4385

>NTDB_id=234119 BB164_RS03265 WP_000796095.1 537379..538452(+) (sepM) [Streptococcus agalactiae strain SG-M25]
MKNRDPKRKHKSLLGLLKWWIIGFAFLLLVLASLVVRLPYYLEMPGGAYDIRSVLKVNKKADKAKGSYNFVAVSVSQATP
AQVLYAWLTPFTELSSKEETTGGFSNDDYLRINQFYMETSQNESIYQALKLANKQVSLTYKGVYVLNLAKNSTFKDRLHL
ADTVTGVNGKSFKNSSQLIKYVAALHLGDKVKVQYTSQGKKKESVGKVIKLSNGKNGIGIGLTDHTEVLSDVPVDFNTEG
VGGPSAGLMFTLAIYDQLVKEDLRKGRKIAGTGTIEQNGHVGDIGGAGLKVVSAAKKGMDIFFVPNNPIDKNAKKGKTKV
QTNYQEAKAAAKRLGTKMKIVPVQNVQQAIDYLKKTK

Nucleotide

• Length: 1074 bp

>NTDB_id=234119 BB164_RS03265 WP_000796095.1 537379..538452(+) (sepM) [Streptococcus agalactiae strain SG-M25]
GTGAAGAATAGAGATCCAAAAAGAAAACATAAAAGTTTACTAGGTCTGCTTAAATGGTGGATTATAGGTTTTGCTTTTTT
ATTGTTAGTATTAGCAAGCCTTGTAGTGAGACTACCTTATTATTTGGAAATGCCAGGTGGAGCTTATGATATCCGTTCGG
TATTGAAAGTGAATAAAAAGGCTGATAAAGCTAAGGGTTCGTACAATTTTGTAGCGGTATCTGTCAGTCAAGCAACGCCA
GCTCAGGTTCTTTATGCTTGGTTAACTCCTTTTACAGAATTATCTAGTAAAGAGGAGACAACAGGTGGCTTTAGTAATGA
CGATTATCTCAGAATTAATCAATTCTACATGGAGACTTCTCAAAATGAGTCCATCTATCAAGCTTTAAAGTTAGCTAATA
AGCAAGTATCTCTTACTTATAAAGGAGTTTATGTGCTTAACTTAGCTAAAAATTCGACATTTAAAGATAGATTACATTTA
GCTGATACAGTCACAGGAGTTAATGGCAAAAGTTTCAAAAATTCTTCTCAACTTATCAAATATGTTGCAGCTCTTCATCT
AGGTGATAAAGTAAAGGTACAATACACAAGTCAAGGTAAAAAGAAAGAATCAGTTGGTAAAGTTATTAAACTATCAAACG
GTAAAAATGGTATTGGTATCGGTTTGACAGACCATACAGAAGTATTATCTGATGTTCCTGTGGACTTTAATACTGAAGGT
GTTGGAGGACCAAGTGCAGGTTTAATGTTTACTTTAGCGATTTACGACCAATTGGTTAAAGAAGATTTACGTAAAGGACG
TAAGATTGCAGGTACTGGTACTATTGAGCAAAATGGGCATGTTGGCGATATTGGTGGAGCAGGTTTGAAAGTTGTTTCAG
CGGCTAAAAAAGGAATGGATATTTTCTTTGTTCCTAATAATCCGATCGATAAAAATGCTAAAAAAGGCAAAACAAAGGTT
CAGACGAATTATCAAGAGGCAAAAGCAGCAGCTAAGCGATTAGGTACGAAGATGAAAATTGTACCAGTTCAAAATGTTCA
GCAAGCTATTGATTATTTGAAAAAAACAAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (137-203)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (242-307)

3D structure

• AlphaFold DB: A0A0E1EG10

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	69.322	94.958	0.658