Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   CCZ24_RS00685 Genome accession   NZ_CP021773
Coordinates   129541..131988 (+) Length   815 a.a.
NCBI ID   WP_000020286.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain B105     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 124541..136988
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CCZ24_RS00660 (CCZ24_00645) ahpC 125546..126106 (-) 561 WP_000060538.1 alkyl hydroperoxide reductase subunit C -
  CCZ24_RS00665 (CCZ24_00650) rpsB 126383..127153 (+) 771 WP_000268454.1 30S ribosomal protein S2 -
  CCZ24_RS00670 (CCZ24_00655) tsf 127247..128287 (+) 1041 WP_000808080.1 translation elongation factor Ts -
  CCZ24_RS00675 (CCZ24_00660) - 128446..128907 (-) 462 WP_112409696.1 small multi-drug export protein -
  CCZ24_RS00680 (CCZ24_00665) - 129080..129544 (+) 465 WP_000985641.1 CtsR family transcriptional regulator -
  CCZ24_RS00685 (CCZ24_00670) clpC 129541..131988 (+) 2448 WP_000020286.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  CCZ24_RS00690 (CCZ24_00675) - 132208..132699 (-) 492 WP_000586900.1 GNAT family N-acetyltransferase -
  CCZ24_RS00695 (CCZ24_00680) - 132713..133354 (-) 642 WP_000909520.1 deoxynucleoside kinase -
  CCZ24_RS00700 (CCZ24_00685) dusB 133475..134452 (-) 978 WP_000192729.1 tRNA dihydrouridine synthase DusB -
  CCZ24_RS00705 (CCZ24_00690) hslO 134436..135311 (-) 876 WP_000357828.1 Hsp33 family molecular chaperone HslO -
  CCZ24_RS00710 (CCZ24_00695) - 135451..136707 (-) 1257 WP_001285395.1 toxic anion resistance protein -

Sequence

Protein


Download         Length: 815 a.a.        Molecular weight: 90627.16 Da        Isoelectric Point: 6.0379

>NTDB_id=233330 CCZ24_RS00685 WP_000020286.1 129541..131988(+) (clpC) [Streptococcus agalactiae strain B105]
MSHYSIKLQEVFRLAQFQAARYESHYLESWHLLLAMVLVHDSVAGLTFAEYESEVAIEEYEAATILALGRAPKEEITNYQ
FLEQSPALKKILKLAENISIVVGAEDVGTEHVLLAMLVNKDLLATRILELVGFRGQDDGESVRMVDLRKALERHAGFTKD
DIKAIYELRNPKKAKSGASFSDMMKPPSTAGDLADFTRDLSQMAVDGEIEPVIGRDKEISRMVQVLSRKTKNNPVLVGDA
GVGKTALAYGLAQRIANGNIPYELRDMRVLELDMMSVVAGTRFRGDFEERMNQIIADIEEDGHIILFIDELHTIMGSGSG
IDSTLDAANILKPALARGTLRTIGATTQEEYQKHIEKDAALSRRFAKVLVEEPNLEDAYEILLGLKPAYEAFHNVTISDE
AVMTAVKVAHRYLTSKNLPDSAIDLLDEASATVQMMIKKNAPSLLTEVDQAILDDDMKSASKALKASHKDKKHKPIAVTE
DHIMATLSRLSGIPVEKLTQADSKKYLNLEKELHKRVIGQDDAVTAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVGKTE
LAKALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQV
LDDGVLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDISHDYTAMQKRIMEELKKAYRPEFINRIDEKVVFHS
LSQDNMREVVKIMVKPLILALKDKGMDLKFQPSALKHLAEDGYDIEMGARPLRRTIQTQVEDHLSELLLANQVKEGQVIK
IGVSKGKLKFDIAKS

Nucleotide


Download         Length: 2448 bp        

>NTDB_id=233330 CCZ24_RS00685 WP_000020286.1 129541..131988(+) (clpC) [Streptococcus agalactiae strain B105]
ATGAGTCATTATTCCATAAAATTACAAGAAGTATTCAGATTGGCGCAATTTCAAGCAGCACGCTATGAAAGTCACTATTT
AGAAAGCTGGCATCTTCTTTTAGCAATGGTTTTAGTTCATGATTCAGTAGCTGGTTTGACATTTGCTGAATATGAGTCTG
AAGTTGCAATTGAAGAGTACGAAGCAGCAACAATTTTAGCTTTAGGTAGAGCACCGAAAGAAGAGATTACCAATTATCAA
TTTTTAGAGCAATCACCAGCTTTGAAAAAGATCTTAAAGTTAGCAGAAAATATTAGTATCGTAGTAGGAGCTGAAGATGT
GGGTACTGAACATGTCTTGCTTGCTATGTTGGTTAATAAAGATTTATTAGCCACACGTATCTTAGAATTAGTTGGCTTTA
GAGGTCAAGACGATGGTGAATCAGTTCGTATGGTTGATTTACGTAAGGCTCTAGAACGTCATGCCGGTTTTACAAAAGAT
GATATCAAAGCAATTTATGAATTACGTAATCCTAAAAAAGCAAAGTCGGGTGCTTCTTTTTCTGATATGATGAAACCACC
AAGTACTGCTGGTGATTTAGCTGATTTCACACGTGATTTATCACAGATGGCGGTTGATGGGGAAATTGAACCTGTTATTG
GGCGTGATAAAGAAATTTCACGTATGGTCCAAGTCTTAAGTCGTAAAACAAAGAATAATCCTGTCTTAGTTGGAGATGCG
GGTGTCGGTAAAACAGCTTTGGCGTACGGTCTAGCACAACGTATTGCTAATGGAAATATTCCTTATGAGCTTAGAGATAT
GCGTGTTCTAGAGTTAGATATGATGAGCGTTGTTGCTGGAACTCGTTTTCGTGGTGATTTTGAGGAACGTATGAATCAAA
TCATTGCAGATATTGAAGAAGACGGTCATATTATTCTTTTCATTGATGAACTGCATACTATTATGGGTTCTGGCTCTGGT
ATTGATAGCACACTTGATGCTGCTAATATTTTAAAACCAGCTTTGGCTCGAGGCACTTTACGCACTATTGGAGCAACAAC
TCAAGAGGAATATCAAAAGCATATTGAAAAAGATGCTGCTTTATCTCGTCGCTTTGCAAAAGTTTTAGTAGAAGAACCAA
ATCTTGAAGACGCATATGAAATTCTACTTGGATTGAAGCCAGCGTATGAAGCCTTTCATAATGTTACCATTTCAGATGAA
GCAGTTATGACTGCTGTAAAAGTGGCTCATCGTTATTTGACAAGTAAGAATTTACCAGACTCAGCTATAGACTTACTTGA
TGAAGCTTCTGCCACTGTGCAAATGATGATTAAGAAAAATGCTCCATCGCTTTTAACAGAAGTTGACCAAGCTATTTTAG
ATGATGATATGAAATCTGCTTCTAAAGCTCTAAAAGCAAGTCATAAGGATAAAAAGCATAAGCCTATTGCCGTAACCGAA
GATCATATTATGGCAACTCTCAGCCGTCTATCTGGTATTCCTGTTGAAAAATTGACACAAGCTGATAGTAAAAAATACCT
CAATTTAGAAAAAGAATTGCATAAACGTGTTATCGGTCAAGATGATGCAGTTACTGCCATTAGTCGTGCTATCCGTCGCA
ATCAATCTGGCATTCGTACTGGTAAGCGTCCTATTGGTTCCTTTATGTTCTTGGGACCAACTGGTGTTGGTAAGACAGAG
TTAGCAAAAGCCTTGGCAGAAGTGTTGTTTGATGATGAATCAGCCCTAATTCGTTTTGATATGTCGGAATATATGGAAAA
ATTCGCAGCTTCTCGCCTGAATGGGGCACCTCCAGGTTATGTTGGTTATGATGAAGGAGGAGAGCTGACTGAAAAAGTAC
GCAATAAACCATATTCAGTTTTACTTTTTGATGAAGTTGAAAAAGCTCATCCAGATATTTTTAATGTATTATTACAAGTG
CTTGATGATGGCGTTTTAACAGATAGTCGAGGACGAAAAGTTGACTTTTCAAATACTATAATCATTATGACTTCTAATTT
AGGAGCAACTGCATTACGTGACGATAAAACAGTTGGTTTTGGAGCTAAGGATATCAGCCATGATTATACTGCTATGCAAA
AACGTATTATGGAGGAGCTTAAAAAAGCTTATCGACCAGAGTTTATCAATCGTATTGATGAGAAAGTTGTATTCCATAGT
CTCAGTCAAGATAATATGCGTGAAGTTGTGAAAATTATGGTTAAACCTTTAATTTTAGCGCTTAAAGATAAAGGTATGGA
TCTGAAATTCCAGCCTTCAGCCTTGAAACACTTGGCAGAGGATGGCTATGATATAGAAATGGGTGCTCGTCCACTGCGTA
GAACTATTCAAACGCAAGTAGAGGATCATTTATCAGAACTACTATTGGCAAATCAAGTGAAAGAGGGGCAAGTAATTAAG
ATTGGCGTATCCAAAGGCAAATTGAAATTTGATATTGCAAAATCATAA

Domains

Predicted by InterproScan.

Clp amino terminal domain, pathogenicity island component (Clp_N)

(105-132)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(15-46)

AAA lid domain (AAA_lid_9)

(375-471)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(721-801)

ATPase family associated with various cellular activities (AAA) (AAA)

(235-367)

AAA domain (Cdc48 subfamily) (AAA_2)

(543-714)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Streptococcus mutans UA159

76.601

99.632

0.763
  clpC Streptococcus thermophilus LMG 18311

72.761

100

0.728
  clpC Streptococcus thermophilus LMD-9

72.638

100

0.726
  clpC Streptococcus pneumoniae Rx1

68.55

99.877

0.685
  clpC Streptococcus pneumoniae D39

68.55

99.877

0.685
  clpC Streptococcus pneumoniae TIGR4

68.55

99.877

0.685
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

48.434

100

0.493
  clpC Bacillus subtilis subsp. subtilis str. 168

45.683

100

0.467
  clpE Streptococcus mutans UA159

46.238

78.282

0.362

Multiple sequence alignment