Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   S101106_RS07835 Genome accession   NZ_CP021674
Coordinates   1461472..1463277 (-) Length   601 a.a.
NCBI ID   WP_015473911.1    Uniprot ID   M5AFG0
Organism   Levilactobacillus brevis strain SRCM101106     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 1455793..1471147 1461472..1463277 within 0


Gene organization within MGE regions


Location: 1455793..1471147
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  S101106_RS07805 (S101106_01592) - 1455793..1456716 (+) 924 WP_087609510.1 IS30 family transposase -
  S101106_RS07810 (S101106_01593) - 1457084..1457980 (-) 897 WP_087609511.1 RluA family pseudouridine synthase -
  S101106_RS07815 (S101106_01594) - 1457977..1458780 (-) 804 WP_021740943.1 NAD kinase -
  S101106_RS07820 (S101106_01595) - 1458782..1459441 (-) 660 WP_011668198.1 GTP pyrophosphokinase family protein -
  S101106_RS07825 (S101106_01596) - 1459755..1460393 (+) 639 WP_011668199.1 ClpXP adapter SpxH family protein -
  S101106_RS07830 (S101106_01597) - 1460555..1461418 (+) 864 WP_085769115.1 DegV family protein -
  S101106_RS07835 (S101106_01598) pepF 1461472..1463277 (-) 1806 WP_015473911.1 oligoendopeptidase F Regulator
  S101106_RS07840 (S101106_01599) - 1463344..1464438 (-) 1095 WP_015473912.1 competence protein CoiA -
  S101106_RS07845 (S101106_01600) trmB 1464565..1465212 (-) 648 WP_015473913.1 tRNA (guanosine(46)-N7)-methyltransferase TrmB -
  S101106_RS07850 (S101106_01601) - 1465278..1466069 (-) 792 WP_011668204.1 phosphotransferase family protein -
  S101106_RS07855 (S101106_01602) - 1466131..1467357 (-) 1227 WP_011668205.1 ABC transporter permease -
  S101106_RS07860 (S101106_01603) - 1467354..1468088 (-) 735 WP_011668206.1 ABC transporter ATP-binding protein -
  S101106_RS07865 (S101106_01604) - 1468298..1468756 (+) 459 WP_011668207.1 HIT family protein -
  S101106_RS07870 (S101106_01605) - 1468759..1469079 (+) 321 WP_015473917.1 hypothetical protein -
  S101106_RS07875 (S101106_01606) - 1469192..1470109 (+) 918 WP_011668209.1 peptidylprolyl isomerase PrsA -
  S101106_RS07880 (S101106_01607) - 1470173..1471147 (-) 975 WP_015473919.1 3'-5' exoribonuclease YhaM family protein -

Sequence

Protein


Download         Length: 601 a.a.        Molecular weight: 67135.10 Da        Isoelectric Point: 4.7804

>NTDB_id=232418 S101106_RS07835 WP_015473911.1 1461472..1463277(-) (pepF) [Levilactobacillus brevis strain SRCM101106]
MKQIPKRSEVPTALTWDLTTIFPDEAAFKAAIAAIKTQTTVVAGLKGQLAQSGAALYRVTTAVFDLNRQLERVYVYASLN
NDQDTGNAAAQALMGQAESLVATVGAATAWFEPEVLALSADQLQTLIDNDPRLADYQHVFDVLGQQRAHTLSVAEEKLLA
GASDIFGASAKTYSVLSDADLKFPVVQDEAGNDVRLSEGLYGVLLQSTTPRVRQQAFEALYSVYQQFRHTFAATLASEVK
THNFSAETRHYASARAAAMSRNNVPAVVYDTLVETVNDHLDSLHRYVNLRKEILDLPQLHMYDLYTPITGEPSLKYTYQE
AQEMALKALAVLGPDYTANVQKMFDGRAIDVVENQGKRTGAYSGGMYDTKPYILLNWQDSLESLFTLVHEMGHSMHSHYT
RTNQPYQYGDYSIFVAEIASTTNENLLTDYLLKTQTDPKVRAYVLNHYLDGFKGTVYRQTQFAEFEDYIHQQDAAGETLT
ADFMSDFYGKLNQRYYGDGVISDPQIADEWTRIPHFYYDYYVYQYATGFAAATTLSQRILSGDEAKRDAYLAYLKAGSSA
LPLDVMKQAGVDMTQPGYLQTAFATFDERLAEFTQLAHELN

Nucleotide


Download         Length: 1806 bp        

>NTDB_id=232418 S101106_RS07835 WP_015473911.1 1461472..1463277(-) (pepF) [Levilactobacillus brevis strain SRCM101106]
GTGAAACAAATTCCGAAACGATCAGAGGTTCCCACGGCACTGACTTGGGACCTGACAACTATTTTTCCCGACGAGGCAGC
TTTTAAGGCCGCAATTGCTGCAATTAAAACGCAAACAACGGTCGTGGCCGGTTTGAAGGGACAATTGGCCCAAAGTGGGG
CCGCGTTATATCGTGTCACGACGGCGGTATTTGATTTGAATCGCCAGTTGGAGCGGGTATATGTCTATGCGTCTTTAAAC
AATGATCAGGATACCGGCAATGCTGCAGCCCAGGCATTAATGGGGCAGGCCGAGAGCTTGGTGGCAACTGTGGGTGCCGC
CACGGCTTGGTTTGAACCTGAGGTATTGGCCTTGTCAGCGGATCAGCTGCAAACGTTGATTGATAACGACCCCCGGCTAG
CAGATTATCAGCATGTGTTTGACGTATTGGGCCAGCAGCGGGCACATACGCTGTCAGTGGCGGAAGAAAAATTGCTAGCG
GGTGCTAGTGATATCTTTGGTGCATCTGCTAAAACTTACAGCGTGCTGAGTGATGCTGATCTAAAGTTTCCAGTTGTTCA
AGACGAAGCCGGCAATGATGTGCGACTGTCAGAAGGACTGTATGGTGTTTTGCTACAATCCACAACACCACGGGTGCGGC
AGCAGGCTTTTGAAGCATTATATTCGGTTTATCAACAATTCCGACATACCTTTGCTGCAACCTTAGCGAGCGAAGTCAAA
ACGCATAATTTTAGTGCTGAGACGCGTCACTATGCGAGTGCCAGAGCGGCAGCGATGAGTCGCAACAATGTGCCAGCGGT
GGTCTATGATACCTTGGTGGAAACAGTCAATGATCATTTAGACTCACTGCATCGCTATGTTAATTTGCGCAAAGAGATTT
TGGACTTGCCACAACTGCACATGTACGACCTGTATACGCCAATTACGGGTGAACCCAGCTTGAAATATACCTACCAAGAA
GCACAAGAGATGGCGTTAAAGGCACTAGCAGTCTTGGGACCGGATTACACTGCCAATGTTCAAAAGATGTTTGATGGCCG
GGCAATTGATGTGGTTGAAAATCAGGGTAAACGGACGGGCGCTTACTCAGGCGGGATGTATGATACTAAACCGTATATTT
TGTTGAATTGGCAAGATAGCTTGGAAAGCTTGTTCACGTTGGTTCATGAGATGGGACACAGCATGCATAGCCATTACACT
CGGACAAATCAACCGTACCAGTATGGTGATTATTCAATCTTTGTTGCGGAAATTGCCTCGACAACGAATGAAAACTTGCT
GACGGACTACCTGTTGAAAACCCAGACTGACCCCAAGGTGCGAGCTTATGTATTAAATCATTATCTGGATGGCTTTAAAG
GCACGGTATACCGCCAGACGCAGTTCGCAGAATTTGAGGACTACATTCACCAACAGGATGCCGCTGGCGAAACTCTGACA
GCTGACTTCATGAGTGATTTCTACGGCAAACTTAATCAGCGTTATTACGGTGATGGCGTGATTTCCGATCCACAAATCGC
TGATGAATGGACCCGAATTCCACATTTCTACTATGACTACTATGTGTACCAGTACGCAACCGGGTTTGCGGCGGCCACGA
CGTTATCGCAACGAATTTTGAGTGGCGACGAGGCAAAGCGGGATGCCTACTTGGCCTATCTAAAGGCGGGAAGTTCTGCC
TTACCACTTGATGTGATGAAACAAGCGGGCGTCGATATGACGCAACCGGGCTATTTGCAAACGGCTTTTGCAACGTTCGA
CGAGCGCTTGGCAGAATTCACGCAATTGGCGCATGAATTAAACTAA

Domains

Predicted by InterproScan.

Oligopeptidase F (Peptidase_M3_N)

(114-183)

Peptidase family M3 (Peptidase_M3)

(204-584)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB M5AFG0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

49.831

98.17

0.489

Multiple sequence alignment