Detailed information NTG0231609

Bioinformatically predicted

Overview

• Name: pilA
• Type: Machinery gene
• Locus tag: CCD86_RS10370
• Genome accession: NZ_CP021518
• Coordinates: 1848258..1849523 (-)
• Length: 421 a.a.
• NCBI ID: WP_002228837.1
• Uniprot ID: A0AB33TWV1
• Organism: Neisseria meningitidis strain 12-176
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1843258..1854523

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CCD86_RS10360 (CCD86_10530)	-	1843782..1844066 (-)	285	WP_002216166.1	GIY-YIG nuclease family protein	-
CCD86_RS10365 (CCD86_10535)	pilC	1844441..1847500 (-)	3060	Protein_1767	PilC family type IV pilus tip adhesin	-
CCD86_RS13175	pilC	1847473..1847598 (-)	126	WP_009344866.1	hypothetical protein	Machinery gene
CCD86_RS10370 (CCD86_10545)	pilA	1848258..1849523 (-)	1266	WP_002228837.1	signal recognition particle-docking protein FtsY	Machinery gene
CCD86_RS10375 (CCD86_10555)	msrAB	1849669..1851237 (+)	1569	WP_002216163.1	bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB	-
CCD86_RS10380 (CCD86_10560)	-	1851339..1851824 (-)	486	WP_002221794.1	CinA family protein	-
CCD86_RS10385 (CCD86_10565)	-	1851850..1852698 (-)	849	WP_002215243.1	mechanosensitive ion channel family protein	-
CCD86_RS10390 (CCD86_10570)	-	1852792..1853793 (-)	1002	WP_002223261.1	thiamine ABC transporter substrate-binding protein	-

Sequence

Protein

• Length: 421 a.a.
• Molecular weight: 45201.50 Da
• Isoelectric Point: 4.5585

>NTDB_id=231609 CCD86_RS10370 WP_002228837.1 1848258..1849523(-) (pilA) [Neisseria meningitidis strain 12-176]
MFSFFRRKKKQETPAPEEAQVQETAAKAESEVTQIVENIKEEVESLTESVKGQVESAVETVSGAVEQVKETVAEMLSEAE
EAAEKAAEQVEAAKEAVAETVGEAVGQVQEAVATTEEHKLGWAARLKQGLTKSRDKMAKSLAGVFGGGQIDEDLYEELET
VLITSDMGMEATEYLMKDVRDRVSLKGLKDGNELRGALKEALYDLIKPLEKPLVLPETKEPFVIMLAGINGAGKTTSIGK
LAKYFQAQGKSVLLAAGDTFRAAAREQLQAWGERNNVTVISQTTGDSAAVCFDAVQAAKARGIDIVLADTAGRLPTQLHL
MEEIKKVKRVLQKAMPDAPHEIIVVLDANIGQNAVNQVKAFDDALGLTGLIVTKLDGTAKGGILAALASDRPVPVRYIGV
GEGIDDLRPFDARAFVDALLD

Nucleotide

• Length: 1266 bp

>NTDB_id=231609 CCD86_RS10370 WP_002228837.1 1848258..1849523(-) (pilA) [Neisseria meningitidis strain 12-176]
ATGTTCAGCTTCTTCCGTCGCAAGAAAAAACAGGAAACGCCGGCTCCCGAGGAGGCTCAAGTTCAGGAAACTGCAGCAAA
AGCAGAATCCGAAGTTACTCAAATAGTTGAAAATATTAAAGAAGAAGTCGAATCTTTAACGGAAAGCGTCAAAGGGCAGG
TCGAATCGGCTGTTGAAACCGTCAGCGGTGCGGTTGAACAGGTAAAGGAAACCGTTGCCGAGATGCTGTCTGAAGCAGAG
GAAGCGGCGGAAAAAGCAGCGGAACAAGTCGAAGCGGCAAAAGAAGCCGTTGCCGAAACCGTCGGCGAGGCTGTCGGGCA
AGTTCAAGAAGCCGTTGCGACAACTGAAGAACACAAGCTCGGTTGGGCGGCGCGTTTGAAACAAGGTTTGACCAAATCGC
GCGACAAAATGGCGAAATCGCTGGCGGGCGTGTTCGGCGGCGGACAAATCGACGAAGATTTGTACGAAGAGCTGGAAACC
GTGCTGATTACCAGCGATATGGGCATGGAAGCCACCGAATACCTGATGAAAGACGTGCGCGACCGCGTCAGCCTCAAAGG
GCTGAAAGACGGCAACGAATTGCGCGGCGCGCTGAAAGAAGCCTTGTACGACCTGATTAAGCCTCTAGAGAAACCGCTGG
TTTTGCCCGAAACCAAAGAGCCGTTTGTCATCATGCTTGCTGGCATCAACGGCGCGGGCAAAACCACATCCATCGGCAAA
CTCGCCAAATATTTCCAAGCGCAGGGCAAATCTGTGCTGCTTGCCGCCGGCGATACTTTCCGCGCCGCCGCGCGTGAGCA
GCTTCAAGCTTGGGGCGAACGCAACAACGTAACCGTGATTTCGCAAACCACGGGCGATTCCGCCGCCGTGTGCTTCGATG
CCGTCCAAGCCGCCAAAGCGCGCGGCATCGACATTGTGCTGGCCGACACCGCCGGCCGCCTGCCCACGCAGCTTCACTTG
ATGGAAGAAATCAAAAAAGTGAAACGCGTGCTGCAAAAAGCCATGCCCGACGCGCCACACGAAATCATCGTCGTGCTTGA
TGCCAATATCGGTCAAAACGCCGTCAACCAAGTCAAAGCCTTTGACGACGCATTGGGGCTGACCGGTTTAATTGTTACCA
AGCTAGACGGCACGGCAAAAGGCGGCATCCTCGCCGCGCTTGCCTCCGACCGCCCCGTCCCCGTCCGCTATATCGGCGTG
GGCGAAGGCATAGACGATTTGCGCCCGTTTGACGCGCGCGCGTTTGTGGACGCACTGCTGGATTGA

Domains

Predicted by InterproScan.

• SRP54-type protein, GTPase domain (SRP54) (221-420)

• SRP54-type protein, helical bundle domain (SRP54_N) (136-202)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilA	Neisseria gonorrhoeae MS11	94.537	100	0.945