Detailed information NTG0231569

Bioinformatically predicted

Overview

• Name: pilC
• Type: Machinery gene
• Locus tag: CCD86_RS00345
• Genome accession: NZ_CP021518
• Coordinates: 57685..60810 (-)
• Length: 1041 a.a.
• NCBI ID: WP_149315872.1
• Uniprot ID: -
• Organism: Neisseria meningitidis strain 12-176
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	61604..62569	57685..60810	flank	794

Gene organization within MGE regions

Location: 57685..62569

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CCD86_RS00345 (CCD86_00365)	pilC	57685..60810 (-)	3126	WP_149315872.1	PilC family type IV pilus tip adhesin	Machinery gene
CCD86_RS00360 (CCD86_00380)	-	61604..62569 (+)	966	WP_002228915.1	IS30-like element IS1655 family transposase	-

Sequence

Protein

• Length: 1041 a.a.
• Molecular weight: 113739.55 Da
• Isoelectric Point: 9.7695

>NTDB_id=231569 CCD86_RS00345 WP_149315872.1 57685..60810(-) (pilC) [Neisseria meningitidis strain 12-176]
MNKTLKRQVFRHTALYAAILMFSHTGGGGGGARAQAETHNYAIVMNKQNQPEVKREGSYSTLREKDRKRKFDFNANNGGG
GSVSFNNSDELVSRQNGTAVFGTATYLPPYGKVSGFDDKRLKERGNAVNWIHTTHPGLIGYSYAGVVCRNSTGCPQLVYK
TRFSFDNTGLAKNAGMLDSHPDPSRENSPIYKLKDYPWLGVSFNLGSENTVKNSQSSNRLISSFSENNNNQTIVSTTESH
PISLGDGQREHTAVVYYLNAKLHLLNKKQIQNITDKTVQLGVLKPSIDVKTQRTGFGGILSFWASWDIKDTGQIPVKLGL
QQVKAGRCVNANNPNKSTKAPSPALTAPALWFGPVQNGKVQMYSASVSTYPDSSSSRIYLQNLKRKDDPGRPGRYSLATL
NKSDIESREPTFTGRQTVIRLDKGVHQIKLKGNEVEGFKGNNGNDTFGIVSEGSFMPDASEWKKVLLPWTVRGFADDSKF
KAFNKEKNNDNKPKYSQRYRIRENGNNGKRDLGDIVNSPIVAVGEYLATSANDGMVHIFKKGNGGDARDYSLKLSYIPGT
MPRKDIQSQDSTLAKELRAFAEKGYVGDRYGVDGGFVLRQVNNLNGQDRVFMFGAMGFGGRGAYALDLTKADGNDPTKAS
LFDVKDNGNNGNNRVELGYTVGTPQIGKTHNGKYAAFLASGYATKEITSGENKTALYVYDLENNNGTPIAKIEVPNGKGG
LSSPTLVDKDLDGTIDIAYAGDRGGKMYRFDLSSQSPDQWTVRPIFEGTKPITSAPAISQLKDKRVVIFGTGSDLSEDDV
DKMDEQYIYGIFDDDTETTGNVKVDLKGLGGGLLEQHLTQEDKTLFLTDYKRSDGSGNKGWVVKLKDGQRVTVKPTVVLR
TAFVTIHKYTGNDKCGAETAILGINTADGGKLTKKSARPIVPDANTKVAQYSGDKKTSSGKSIPIGCMQKGNEIVCPNGY
VYDKPVNVRYLDEKKTDGFSTTADGDAGGSGIDPAGKRSGKNNRCFSQKGVRTLLMNDLDSLDITGPTCGMKRISWREIF
Y

Nucleotide

• Length: 3126 bp

>NTDB_id=231569 CCD86_RS00345 WP_149315872.1 57685..60810(-) (pilC) [Neisseria meningitidis strain 12-176]
ATGAATAAAACTTTAAAAAGGCAGGTTTTCCGCCATACCGCGCTTTATGCCGCCATCTTGATGTTTTCCCATACCGGCGG
GGGGGGGGGGGGGGCGCGCGCGCAGGCGGAAACCCATAACTACGCTATTGTCATGAACAAACAAAATCAGCCGGAGGTAA
AGCGGGAGGGTTCATATTCAACCTTAAGGGAAAAAGACAGGAAACGCAAATTTGACTTTAATGCGAACAACGGGGGTGGA
GGCTCTGTCTCATTCAACAATAGCGATGAGCTTGTTTCTCGACAAAACGGTACTGCCGTTTTTGGCACAGCCACCTACCT
GCCGCCCTACGGCAAGGTTTCCGGTTTTGATGACAAAAGGCTGAAAGAGCGCGGCAATGCCGTTAATTGGATTCATACGA
CCCACCCAGGGTTGATAGGCTACAGCTACGCCGGTGTCGTATGCAGAAACAGCACAGGCTGTCCCCAACTTGTCTATAAA
ACCCGATTTTCCTTCGACAACACCGGTTTGGCAAAAAATGCGGGCATGCTGGATAGTCACCCGGACCCAAGCCGCGAAAA
TTCGCCCATTTACAAATTGAAAGATTATCCATGGTTGGGCGTATCTTTCAATTTGGGCAGCGAGAATACCGTCAAAAATA
GCCAATCATCCAACAGATTGATATCTTCTTTTAGTGAAAACAATAATAATCAAACCATCGTCTCTACGACAGAAAGCCAC
CCTATTTCCCTTGGCGACGGGCAGCGCGAACATACCGCCGTGGTCTATTATCTGAACGCCAAGCTGCACCTGCTGAATAA
AAAACAGATTCAAAATATCACCGACAAAACAGTGCAGTTGGGTGTCTTGAAGCCGAGCATCGATGTGAAGACACAAAGGA
CGGGGTTTGGCGGCATTCTATCTTTTTGGGCTAGTTGGGACATTAAAGATACCGGGCAGATTCCAGTCAAGCTCGGCCTG
CAGCAAGTCAAAGCAGGCCGCTGCGTCAACGCAAATAACCCCAATAAGAGTACCAAAGCCCCTTCCCCCGCCCTGACTGC
CCCCGCGCTGTGGTTCGGACCTGTGCAAAATGGTAAGGTGCAGATGTATTCCGCTTCGGTTTCCACCTACCCCGACAGTT
CGAGCAGCCGCATCTACCTTCAAAATCTGAAAAGAAAAGACGACCCCGGCAGACCCGGCCGCTATTCCCTCGCAACCTTG
AATAAGTCGGATATTGAAAGTCGAGAGCCGACTTTCACAGGGCGGCAAACCGTCATCCGATTGGATAAAGGCGTACATCA
GATCAAACTTAAAGGCAATGAGGTCGAAGGTTTTAAGGGAAACAACGGCAACGACACTTTCGGCATTGTTAGTGAAGGGA
GCTTCATGCCTGATGCCAGCGAGTGGAAAAAAGTGCTGCTGCCTTGGACGGTTCGGGGTTTTGCTGATGACAGTAAATTT
AAAGCATTCAACAAAGAAAAAAACAACGACAACAAGCCAAAATACAGCCAAAGATACCGCATCCGCGAAAACGGCAACAA
CGGCAAGCGCGATTTGGGCGACATCGTCAACAGCCCCATCGTGGCGGTCGGCGAGTATTTGGCTACTTCCGCCAACGACG
GGATGGTGCATATCTTCAAAAAAGGCAACGGCGGGGACGCGCGCGACTATAGTCTGAAGCTCAGCTACATCCCGGGCACG
ATGCCGCGCAAGGATATTCAAAGTCAAGACTCCACCCTCGCCAAAGAGCTGCGCGCCTTTGCCGAAAAAGGCTATGTGGG
CGACCGCTACGGCGTGGACGGCGGCTTTGTCTTGCGCCAAGTTAACAACTTAAATGGGCAAGACCGCGTGTTTATGTTCG
GCGCGATGGGCTTTGGCGGCAGAGGTGCGTATGCCTTGGATTTGACCAAAGCCGACGGCAATGACCCGACAAAAGCCTCT
TTGTTTGATGTAAAAGATAATGGCAATAACGGCAATAATCGCGTGGAATTAGGCTACACCGTCGGCACGCCGCAAATCGG
CAAAACCCACAACGGCAAATACGCCGCTTTCCTCGCCTCCGGTTATGCGACTAAAGAAATTACCAGCGGCGAGAATAAAA
CCGCGCTGTATGTGTATGATTTGGAAAACAACAACGGTACGCCGATTGCAAAAATCGAAGTACCCAACGGCAAGGGCGGG
CTTTCGTCCCCCACGCTGGTGGATAAAGATTTGGACGGCACAATCGATATCGCCTATGCCGGCGATCGCGGCGGGAAAAT
GTACCGCTTTGATTTGAGCAGTCAAAGTCCTGATCAATGGACTGTACGCCCTATTTTTGAAGGCACAAAACCGATTACTT
CCGCGCCCGCCATTTCCCAACTGAAAGACAAACGCGTGGTCATCTTCGGCACGGGCAGCGATTTGAGTGAGGATGATGTT
GATAAAATGGACGAACAATATATTTACGGTATCTTCGACGACGATACGGAGACGACGGGTAATGTAAAGGTAGACCTTAA
AGGTTTGGGAGGCGGGCTGCTCGAGCAACACCTTACTCAGGAAGATAAAACCTTATTCCTGACCGATTATAAGCGATCCG
ACGGCTCGGGCAATAAGGGCTGGGTAGTGAAATTGAAGGACGGACAGCGCGTTACCGTCAAACCGACCGTGGTATTGCGT
ACCGCCTTTGTAACCATCCATAAATATACGGGTAATGACAAATGCGGCGCGGAAACCGCCATTTTGGGCATCAATACCGC
CGACGGCGGCAAGCTGACCAAGAAAAGCGCGCGCCCGATTGTGCCGGACGCCAATACGAAGGTCGCGCAATATTCCGGCG
ATAAGAAAACTTCCAGCGGCAAATCCATCCCTATAGGTTGTATGCAAAAAGGCAATGAAATCGTCTGCCCGAACGGATAT
GTTTACGACAAACCGGTTAATGTGCGTTATCTGGATGAAAAGAAAACAGACGGATTTTCAACAACGGCAGACGGCGATGC
GGGCGGCAGCGGTATAGACCCCGCCGGCAAGCGTTCCGGCAAAAACAACCGCTGCTTCTCCCAAAAAGGGGTGCGCACCC
TGCTGATGAACGATTTGGACAGCTTGGACATTACCGGCCCGACGTGCGGTATGAAACGAATCAGCTGGCGTGAAATCTTC
TACTGA

Domains

Predicted by InterproScan.

• Neisseria PilC beta-propeller domain (T4P_PilY1) (512-848)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilC	Neisseria meningitidis A1493	79.504	100	0.801