Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   C5097_RS22190 Genome accession   NZ_CP027105
Coordinates   4190554..4191186 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain RM14721     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4185554..4196186
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C5097_RS22160 (C5097_22145) yheS 4185723..4187636 (+) 1914 WP_089588063.1 ABC transporter ATP-binding protein -
  C5097_RS22165 (C5097_22150) yheT 4187636..4188658 (+) 1023 WP_000057356.1 hydrolase -
  C5097_RS22170 (C5097_22155) yheU 4188652..4188870 (+) 219 WP_000907085.1 YheU family protein -
  C5097_RS22175 (C5097_22160) prkB 4188924..4189793 (+) 870 WP_001274680.1 phosphoribulokinase -
  C5097_RS22180 (C5097_22165) yhfA 4189848..4190252 (-) 405 WP_001148908.1 OsmC family protein -
  C5097_RS22190 (C5097_22175) crp 4190554..4191186 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  C5097_RS22195 (C5097_22180) yhfK 4191237..4193327 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  C5097_RS22200 (C5097_22185) argD 4193394..4194614 (-) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  C5097_RS22205 (C5097_22190) pabA 4194700..4195263 (-) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  C5097_RS22210 (C5097_22195) fic 4195295..4195897 (-) 603 WP_089588064.1 putative adenosine monophosphate-protein transferase Fic -
  C5097_RS22215 (C5097_22200) yhfG 4195887..4196054 (-) 168 WP_000736860.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=230149 C5097_RS22190 WP_000242755.1 4190554..4191186(+) (crp) [Escherichia coli strain RM14721]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=230149 C5097_RS22190 WP_000242755.1 4190554..4191186(+) (crp) [Escherichia coli strain RM14721]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment