Detailed information NTG0022972

Bioinformatically predicted

Overview

• Name: braR
• Type: Regulator
• Locus tag: SMU_RS04640
• Genome accession: NC_004350
• Coordinates: 963169..963840 (+)
• Length: 223 a.a.
• NCBI ID: WP_002263237.1
• Uniprot ID: Q8DUD1
• Organism: Streptococcus mutans UA159
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 958169..968840

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SMU_RS04630 (SMU.1006)	-	960370..961122 (+)	753	WP_002263239.1	ABC transporter ATP-binding protein	-
SMU_RS04635 (SMU.1007)	-	961124..963127 (+)	2004	WP_002263238.1	ABC transporter permease	-
SMU_RS04640 (SMU.1008)	braR	963169..963840 (+)	672	WP_002263237.1	DNA-binding response regulator	Regulator
SMU_RS04645 (SMU.1009)	-	963837..964790 (+)	954	WP_002263236.1	sensor histidine kinase	-
SMU_RS04650 (SMU.1010)	citC	964941..965990 (-)	1050	WP_002263235.1	[citrate (pro-3S)-lyase] ligase	-
SMU_RS04655 (SMU.1011)	citG	966166..967056 (-)	891	WP_002263234.1	triphosphoribosyl-dephospho-CoA synthase CitG	-
SMU_RS04660 (SMU.1012c)	-	967062..967751 (-)	690	WP_002263233.1	GntR family transcriptional regulator	-

Sequence

Protein

• Length: 223 a.a.
• Molecular weight: 25802.90 Da
• Isoelectric Point: 5.1691

>NTDB_id=22972 SMU_RS04640 WP_002263237.1 963169..963840(+) (braR) [Streptococcus mutans UA159]
MLKQEKIYLVEDDTTIVNLLKNHLGQHYQVKSVDNFRAILQEVKEFKPDLILMDITLPYFNGFYWTTEIRKSMTMPIIFI
SSADEEMNAVMAMNMGGDDFLSKPFSLPILDAKIAAFLRRANEFTKQGHQIEEFELTLDGVFSNLERQETIQLTPTETKI
LSLLIDYKGEVVTKEALLNRLWEGEEFIDQNTLSVNMTRLRKKVLSVSFDKIHTVRGVGYLIK

Nucleotide

• Length: 672 bp

>NTDB_id=22972 SMU_RS04640 WP_002263237.1 963169..963840(+) (braR) [Streptococcus mutans UA159]
ATGCTAAAGCAAGAAAAAATTTACTTGGTTGAAGATGATACAACCATTGTCAATCTTTTAAAGAATCATTTGGGACAACA
CTATCAAGTTAAAAGCGTTGATAACTTTAGGGCTATCTTGCAAGAAGTTAAAGAATTTAAACCCGATTTAATTCTGATGG
ATATTACTTTGCCCTATTTCAATGGCTTTTATTGGACTACTGAAATCAGAAAGAGCATGACCATGCCCATTATCTTTATT
TCCAGTGCTGATGAAGAAATGAATGCAGTAATGGCTATGAATATGGGAGGTGATGATTTTTTGAGCAAGCCTTTCTCGCT
GCCTATTTTGGATGCCAAAATCGCTGCTTTCTTGCGCCGTGCTAACGAGTTCACTAAGCAAGGCCATCAAATTGAAGAGT
TTGAATTAACGTTAGATGGTGTATTCTCAAATTTAGAAAGACAAGAGACTATCCAATTGACTCCAACAGAAACGAAAATT
CTTTCCTTACTTATTGATTATAAAGGAGAGGTTGTCACTAAGGAAGCTCTTCTCAACCGACTATGGGAGGGAGAGGAATT
TATTGATCAAAACACGCTTAGTGTTAATATGACACGTCTTCGTAAAAAGGTTCTATCAGTAAGTTTTGATAAGATTCATA
CAGTAAGAGGAGTAGGGTATTTAATTAAATGA

Domains

Predicted by InterProScan.

• Response regulator receiver domain (Response_reg) (7-114)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (149-221)

3D structure

• AlphaFold DB: Q8DUD1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braR	Staphylococcus aureus N315	43.498	100	0.435