Detailed information NTG0229467

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: RK73_RS07210
• Genome accession: NZ_CP026960
• Coordinates: 1357209..1358252 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: Q99SZ7
• Organism: Staphylococcus aureus strain FDAARGOS_15
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1352209..1363252

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RK73_RS07180 (RK73_07180)	-	1352627..1353883 (-)	1257	WP_001795438.1	aminopeptidase	-
RK73_RS07185 (RK73_07185)	-	1353886..1354086 (-)	201	WP_000180461.1	DUF1128 family protein	-
RK73_RS07190 (RK73_07190)	-	1354233..1354697 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
RK73_RS07195 (RK73_07195)	-	1354704..1354979 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
RK73_RS07200 (RK73_07200)	-	1355257..1356474 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
RK73_RS07205 (RK73_07205)	vraR	1356590..1357219 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
RK73_RS07210 (RK73_07210)	vraS	1357209..1358252 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
RK73_RS07215 (RK73_07215)	liaF	1358249..1358950 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
RK73_RS07220 (RK73_07220)	-	1358965..1359351 (-)	387	WP_001110179.1	hypothetical protein	-
RK73_RS07225 (RK73_07225)	map	1359568..1360326 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
RK73_RS07240 (RK73_07240)	-	1360854..1361840 (+)	987	WP_000999713.1	FUSC family protein	-
RK73_RS07250 (RK73_07250)	-	1362271..1362684 (-)	414	WP_001549145.1	hypothetical protein	-
RK73_RS07255 (RK73_07255)	-	1362713..1362823 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=229467 RK73_RS07210 WP_001017131.1 1357209..1358252(-) (vraS) [Staphylococcus aureus strain FDAARGOS_15]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=229467 RK73_RS07210 WP_001017131.1 1357209..1358252(-) (vraS) [Staphylococcus aureus strain FDAARGOS_15]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterProScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: Q99SZ7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1