Detailed information NTG0228855

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: B5M25_RS13960
• Genome accession: NZ_CP021171
• Coordinates: 2671675..2672562 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain CHU15-056
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2666675..2677562

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
B5M25_RS13925 (B5M25_13755)	-	2666694..2666786 (+)	93	WP_010956583.1	hypothetical protein	-
B5M25_RS13930 (B5M25_13760)	-	2666894..2667391 (-)	498	WP_001065268.1	glutathione peroxidase	-
B5M25_RS13935 (B5M25_13765)	-	2667401..2667661 (-)	261	WP_001791974.1	hypothetical protein	-
B5M25_RS13945 (B5M25_13775)	-	2668043..2668156 (-)	114	Protein_2596	hypothetical protein	-
B5M25_RS13950 (B5M25_13780)	-	2668815..2670815 (-)	2001	WP_000776751.1	ABC transporter permease	-
B5M25_RS13955 (B5M25_13785)	-	2670812..2671567 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
B5M25_RS13960 (B5M25_13790)	braS	2671675..2672562 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
B5M25_RS13965 (B5M25_13795)	braR	2672573..2673238 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
B5M25_RS13970 (B5M25_13800)	-	2673264..2673464 (-)	201	WP_000604730.1	hypothetical protein	-
B5M25_RS13975 (B5M25_13805)	-	2673662..2675086 (+)	1425	WP_000953755.1	alkaline phosphatase	-
B5M25_RS14470	-	2675156..2675266 (+)	111	Protein_2603	hypothetical protein	-
B5M25_RS13985 (B5M25_13815)	-	2675369..2675824 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
B5M25_RS13990 (B5M25_13820)	-	2676069..2676830 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=228855 B5M25_RS13960 WP_000143425.1 2671675..2672562(-) (braS) [Staphylococcus aureus strain CHU15-056]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=228855 B5M25_RS13960 WP_000143425.1 2671675..2672562(-) (braS) [Staphylococcus aureus strain CHU15-056]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1