Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   AM456_RS18960 Genome accession   NZ_CP026755
Coordinates   3523173..3523805 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain AR_0077     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3518173..3528805
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AM456_RS18930 (AM456_18955) yheS 3518342..3520255 (+) 1914 WP_094030152.1 ABC transporter ATP-binding protein -
  AM456_RS18935 (AM456_18960) yheT 3520255..3521277 (+) 1023 WP_000057370.1 hydrolase -
  AM456_RS18940 (AM456_18965) yheU 3521271..3521489 (+) 219 WP_024704858.1 YheU family protein -
  AM456_RS18945 (AM456_18970) prkB 3521543..3522412 (+) 870 WP_001274680.1 phosphoribulokinase -
  AM456_RS18950 (AM456_18975) yhfA 3522467..3522871 (-) 405 WP_001148908.1 OsmC family protein -
  AM456_RS18960 (AM456_18985) crp 3523173..3523805 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  AM456_RS18965 (AM456_18990) yhfK 3523856..3525946 (+) 2091 WP_122992252.1 YccS/YhfK family putative transporter -
  AM456_RS18970 (AM456_18995) argD 3526009..3527232 (-) 1224 WP_000963789.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  AM456_RS18975 (AM456_19000) pabA 3527318..3527881 (-) 564 WP_000601848.1 aminodeoxychorismate synthase component 2 -
  AM456_RS18980 (AM456_19005) fic 3527913..3528515 (-) 603 WP_001280654.1 putative adenosine monophosphate-protein transferase Fic -
  AM456_RS18985 (AM456_19010) yhfG 3528505..3528672 (-) 168 WP_000736860.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=228571 AM456_RS18960 WP_000242755.1 3523173..3523805(+) (crp) [Escherichia coli strain AR_0077]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=228571 AM456_RS18960 WP_000242755.1 3523173..3523805(+) (crp) [Escherichia coli strain AR_0077]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAAGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACTGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTTCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCGGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACAGTGGGGCGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment