Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   C4J65_RS13615 Genome accession   NZ_CP026730
Coordinates   2995515..2996177 (+) Length   220 a.a.
NCBI ID   WP_115742661.1    Uniprot ID   -
Organism   Streptomyces sp. CB09001     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2990515..3001177
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C4J65_RS13585 (C4J65_13570) - 2990932..2991474 (+) 543 WP_240330417.1 hypothetical protein -
  C4J65_RS13590 (C4J65_13575) - 2991539..2992465 (-) 927 WP_162833174.1 aminoglycoside 3'-phosphotransferase/choline kinase family protein -
  C4J65_RS13595 (C4J65_13580) - 2992562..2993065 (+) 504 WP_115742657.1 DUF4396 domain-containing protein -
  C4J65_RS13600 (C4J65_13585) - 2993115..2993525 (-) 411 WP_115742658.1 four-helix bundle copper-binding protein -
  C4J65_RS13605 (C4J65_13590) - 2993617..2993988 (-) 372 WP_115742659.1 DUF6223 family protein -
  C4J65_RS13610 (C4J65_13595) - 2994253..2995518 (+) 1266 WP_115742660.1 sensor histidine kinase -
  C4J65_RS13615 (C4J65_13600) vraR 2995515..2996177 (+) 663 WP_115742661.1 response regulator transcription factor Regulator
  C4J65_RS13620 (C4J65_13605) - 2996257..2996919 (+) 663 WP_115742662.1 precorrin-8X methylmutase -
  C4J65_RS13625 (C4J65_13610) - 2996954..2997742 (-) 789 WP_115742663.1 cobalt-precorrin-6A reductase -
  C4J65_RS13635 (C4J65_13620) - 2998184..2999464 (+) 1281 WP_115742664.1 RNA-guided endonuclease TnpB family protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23801.46 Da        Isoelectric Point: 5.5988

>NTDB_id=228394 C4J65_RS13615 WP_115742661.1 2995515..2996177(+) (vraR) [Streptomyces sp. CB09001]
MIRVLLVDDQPLVRSGFRALLDLEDDIEVVAEAGDGREGLALAGELRPDIALVDVQMPVLDGIETTRRIAADPALAGVHV
VVLTNYGMDEYVFEALRAGAAGFLVKDILPDDLVHAVRVAARGEALLAPSITRRLIDHYVSRPLHHDAGTRLAELTGRER
EAVALVAQGLSNDEIAARLVISPLTAKTHVNRAMAKLHVRDRAQLVVLAYESGLVAPRPR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=228394 C4J65_RS13615 WP_115742661.1 2995515..2996177(+) (vraR) [Streptomyces sp. CB09001]
TTGATCCGTGTCCTGCTCGTCGACGACCAGCCGCTCGTGCGCAGCGGCTTCCGCGCCCTGCTCGACCTCGAGGACGACAT
CGAGGTGGTGGCCGAGGCGGGCGACGGCAGGGAGGGCCTGGCCCTTGCCGGGGAACTGCGGCCCGACATCGCGCTCGTCG
ACGTGCAGATGCCGGTCCTGGACGGCATCGAGACCACCCGGCGCATCGCTGCCGACCCGGCGCTGGCGGGCGTGCACGTC
GTCGTCCTGACCAACTACGGCATGGACGAGTACGTCTTCGAGGCGCTGCGCGCGGGCGCCGCCGGATTCCTCGTCAAGGA
CATCCTCCCGGACGACCTCGTGCACGCCGTGCGGGTCGCGGCCCGCGGCGAGGCGCTGCTGGCTCCGTCGATCACCCGCA
GGCTGATCGACCACTACGTCAGCCGTCCGCTCCACCACGACGCCGGTACCCGGCTGGCGGAGCTGACCGGACGCGAACGC
GAGGCCGTCGCACTGGTCGCGCAGGGGCTGTCCAACGACGAGATCGCGGCCCGCCTGGTGATCAGCCCGCTGACCGCGAA
GACCCACGTCAACCGTGCCATGGCCAAGCTGCACGTCCGCGACCGGGCGCAACTCGTCGTCCTCGCCTACGAGTCGGGCC
TGGTCGCTCCCCGCCCCCGTTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-118)

Bacterial regulatory proteins, luxR family (GerE)

(155-209)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

37.85

97.273

0.368

Multiple sequence alignment