Detailed information    

insolico Bioinformatically predicted

Overview


Name   comS   Type   Regulator
Locus tag   SPS_RS10395 Genome accession   NC_004606
Coordinates   48475..48573 (+) Length   32 a.a.
NCBI ID   WP_020833188.1    Uniprot ID   -
Organism   Streptococcus pyogenes SSI-1     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context


Location: 43475..53573
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPS_RS00250 (SPs0030) - 44341..45681 (+) 1341 WP_002986685.1 hypothetical protein -
  SPS_RS00255 (SPs0031) purB 46050..47342 (+) 1293 WP_011054098.1 adenylosuccinate lyase -
  SPS_RS00260 (SPs0032) comR 47473..48384 (+) 912 WP_011054099.1 helix-turn-helix domain-containing protein Regulator
  SPS_RS10395 comS 48475..48573 (+) 99 WP_020833188.1 quorum-sensing system DWW-type pheromone Regulator
  SPS_RS00265 (SPs0033) ruvB 48604..49602 (+) 999 WP_011054100.1 Holliday junction branch migration DNA helicase RuvB -
  SPS_RS00270 (SPs0034) - 49740..50177 (+) 438 WP_002994668.1 low molecular weight protein-tyrosine-phosphatase -
  SPS_RS00275 (SPs0035) - 50200..50601 (+) 402 WP_011017240.1 MORN repeat-containing protein -
  SPS_RS00280 (SPs0036) - 50598..52373 (+) 1776 WP_011054101.1 acyltransferase family protein -

Sequence


Protein


Download         Length: 32 a.a.        Molecular weight: 3758.63 Da        Isoelectric Point: 10.7919

>NTDB_id=22831 SPS_RS10395 WP_020833188.1 48475..48573(+) (comS) [Streptococcus pyogenes SSI-1]
MLKKVKPFLLLAAVVAFKVARVMHEFDWWNLG

Nucleotide


Download         Length: 99 bp        

>NTDB_id=22831 SPS_RS10395 WP_020833188.1 48475..48573(+) (comS) [Streptococcus pyogenes SSI-1]
ATGTTAAAAAAAGTTAAGCCATTTTTACTATTAGCCGCAGTAGTTGCATTTAAAGTTGCTCGTGTAATGCATGAATTTGA
TTGGTGGAATCTTGGTTAA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comS Streptococcus pyogenes MGAS315

100

100

1

  comS Streptococcus pyogenes MGAS8232

45.161

96.875

0.437


Multiple sequence alignment