Detailed information NTG0228231

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: B4893_RS13765
• Genome accession: NZ_CP021105
• Coordinates: 2643918..2644805 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain CC5
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2638918..2649805

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
B4893_RS13730 (B4893_13595)	-	2638937..2639029 (+)	93	WP_010956583.1	hypothetical protein	-
B4893_RS13735 (B4893_13600)	-	2639137..2639634 (-)	498	WP_001065268.1	glutathione peroxidase	-
B4893_RS13740 (B4893_13605)	-	2639644..2639904 (-)	261	WP_001791974.1	hypothetical protein	-
B4893_RS13750 (B4893_13615)	-	2640286..2640399 (-)	114	Protein_2552	hypothetical protein	-
B4893_RS13755 (B4893_13620)	-	2641058..2643058 (-)	2001	WP_000776751.1	ABC transporter permease	-
B4893_RS13760 (B4893_13625)	-	2643055..2643810 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
B4893_RS13765 (B4893_13630)	braS	2643918..2644805 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
B4893_RS13770 (B4893_13635)	braR	2644816..2645481 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
B4893_RS13775 (B4893_13640)	-	2645507..2645707 (-)	201	WP_000604730.1	hypothetical protein	-
B4893_RS13780 (B4893_13645)	-	2645905..2647329 (+)	1425	WP_000953755.1	alkaline phosphatase	-
B4893_RS14465 (B4893_13650)	-	2647389..2647490 (-)	102	WP_000731976.1	SE2200 family small protein	-
B4893_RS13790 (B4893_13655)	-	2647612..2648067 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
B4893_RS13795 (B4893_13660)	-	2648312..2649073 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=228231 B4893_RS13765 WP_000143425.1 2643918..2644805(-) (braS) [Staphylococcus aureus strain CC5]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=228231 B4893_RS13765 WP_000143425.1 2643918..2644805(-) (braS) [Staphylococcus aureus strain CC5]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1