Detailed information
Bioinformatically predicted
Overview
| Name | ccrB | Type | Machinery gene |
| Locus tag | MCCS_RS00220 | Genome accession | NZ_CP021059 |
| Coordinates | 39914..41542 (-) | Length | 542 a.a. |
| NCBI ID | WP_086041447.1 | Uniprot ID | A0A0D6DQZ6 |
| Organism | Macrococcoides canis strain KM 45013 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 1619..49752 | 39914..41542 | within | 0 |
Gene organization within MGE regions
Location: 1619..49752
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MCCS_RS00010 (MCCS_00020) | dnaN | 1619..2752 (+) | 1134 | WP_086041409.1 | DNA polymerase III subunit beta | - |
| MCCS_RS00015 (MCCS_00030) | - | 2852..3748 (+) | 897 | WP_086041410.1 | ABC transporter ATP-binding protein | - |
| MCCS_RS00020 (MCCS_00040) | - | 3741..4982 (+) | 1242 | WP_086041411.1 | ABC transporter permease | - |
| MCCS_RS00025 (MCCS_00050) | - | 5072..5776 (+) | 705 | WP_086041412.1 | thioredoxin domain-containing protein | - |
| MCCS_RS00030 (MCCS_00060) | - | 5776..6192 (+) | 417 | WP_086041413.1 | disulfide oxidoreductase | - |
| MCCS_RS00035 (MCCS_00070) | yaaA | 6331..6552 (+) | 222 | WP_086041414.1 | S4 domain-containing protein YaaA | - |
| MCCS_RS00040 (MCCS_00080) | recF | 6549..7658 (+) | 1110 | WP_086041415.1 | DNA replication/repair protein RecF | - |
| MCCS_RS00045 (MCCS_00090) | gyrB | 7666..9594 (+) | 1929 | WP_193432090.1 | DNA topoisomerase (ATP-hydrolyzing) subunit B | - |
| MCCS_RS00050 (MCCS_00100) | gyrA | 9622..12276 (+) | 2655 | WP_086041416.1 | DNA gyrase subunit A | - |
| MCCS_RS00055 (MCCS_00110) | alsS | 12472..14139 (+) | 1668 | WP_086041417.1 | acetolactate synthase AlsS | - |
| MCCS_RS00060 (MCCS_00120) | budA | 14150..14851 (+) | 702 | WP_086041418.1 | acetolactate decarboxylase | - |
| MCCS_RS00065 (MCCS_00130) | - | 15010..15828 (-) | 819 | WP_086041419.1 | NAD(P)H-hydrate dehydratase | - |
| MCCS_RS00070 (MCCS_00150) | serS | 16174..17445 (+) | 1272 | WP_086041420.1 | serine--tRNA ligase | - |
| MCCS_RS00075 (MCCS_00160) | - | 17674..18189 (+) | 516 | WP_086041421.1 | YceI family protein | - |
| MCCS_RS00080 (MCCS_00170) | - | 18323..19234 (+) | 912 | WP_086041422.1 | DUF2232 domain-containing protein | - |
| MCCS_RS00085 (MCCS_00180) | - | 19264..21231 (+) | 1968 | WP_086041423.1 | DHH family phosphoesterase | - |
| MCCS_RS00090 (MCCS_00190) | rplI | 21234..21680 (+) | 447 | WP_086041424.1 | 50S ribosomal protein L9 | - |
| MCCS_RS00095 (MCCS_00200) | dnaB | 21698..23104 (+) | 1407 | WP_086041425.1 | replicative DNA helicase | - |
| MCCS_RS00100 (MCCS_00220) | - | 23427..24716 (+) | 1290 | WP_086041426.1 | adenylosuccinate synthase | - |
| MCCS_RS00105 (MCCS_00230) | - | 24925..25812 (-) | 888 | WP_086041427.1 | YitT family protein | - |
| MCCS_RS00120 (MCCS_00260) | yycF | 26232..26933 (+) | 702 | WP_086041428.1 | response regulator YycF | - |
| MCCS_RS00125 (MCCS_00270) | walK | 26938..28776 (+) | 1839 | WP_086041429.1 | cell wall metabolism sensor histidine kinase WalK | - |
| MCCS_RS00130 (MCCS_00280) | - | 28769..30082 (+) | 1314 | WP_167625936.1 | YycH family regulatory protein | - |
| MCCS_RS00135 (MCCS_00290) | - | 30082..30873 (+) | 792 | WP_086041431.1 | two-component system regulatory protein YycI | - |
| MCCS_RS00140 (MCCS_00300) | - | 30891..31682 (+) | 792 | WP_086041432.1 | MBL fold metallo-hydrolase | - |
| MCCS_RS00145 (MCCS_00310) | rlmH | 31942..32421 (+) | 480 | WP_086041433.1 | 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH | - |
| MCCS_RS00150 (MCCS_00320) | - | 32568..33110 (+) | 543 | WP_086041434.1 | hypothetical protein | - |
| MCCS_RS00155 (MCCS_00330) | - | 33150..34049 (-) | 900 | WP_086041435.1 | site-specific DNA-methyltransferase | - |
| MCCS_RS00160 (MCCS_00340) | - | 34113..34499 (-) | 387 | WP_086041436.1 | hypothetical protein | - |
| MCCS_RS00165 (MCCS_00350) | - | 34659..34850 (-) | 192 | WP_041636569.1 | hypothetical protein | - |
| MCCS_RS00170 (MCCS_00360) | - | 34853..35194 (-) | 342 | WP_086041437.1 | hypothetical protein | - |
| MCCS_RS00175 (MCCS_00370) | - | 35209..35652 (-) | 444 | WP_086041438.1 | hypothetical protein | - |
| MCCS_RS00180 (MCCS_00380) | - | 35675..35959 (-) | 285 | WP_086041439.1 | hypothetical protein | - |
| MCCS_RS00185 (MCCS_00390) | - | 35974..36198 (-) | 225 | WP_086041440.1 | hypothetical protein | - |
| MCCS_RS00190 (MCCS_00400) | - | 36218..36694 (-) | 477 | WP_086041441.1 | hypothetical protein | - |
| MCCS_RS00195 (MCCS_00410) | - | 36663..37583 (-) | 921 | WP_086041442.1 | YafY family protein | - |
| MCCS_RS00200 (MCCS_00420) | - | 37765..38208 (-) | 444 | WP_086041443.1 | RadC family protein | - |
| MCCS_RS00205 (MCCS_00430) | - | 38230..38733 (-) | 504 | WP_086041444.1 | DUF1643 domain-containing protein | - |
| MCCS_RS00210 (MCCS_00440) | - | 38746..39078 (-) | 333 | WP_086041445.1 | DUF960 family protein | - |
| MCCS_RS00215 (MCCS_00450) | - | 39142..39504 (-) | 363 | WP_086041446.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| MCCS_RS00220 (MCCS_00460) | ccrB | 39914..41542 (-) | 1629 | WP_086041447.1 | recombinase family protein | Machinery gene |
| MCCS_RS00225 (MCCS_00470) | - | 41607..42977 (-) | 1371 | WP_167625937.1 | recombinase family protein | - |
| MCCS_RS00230 (MCCS_00480) | - | 43149..44900 (-) | 1752 | WP_086041449.1 | DUF927 domain-containing protein | - |
| MCCS_RS00235 (MCCS_00490) | - | 45081..45722 (-) | 642 | WP_086041450.1 | hypothetical protein | - |
| MCCS_RS00240 (MCCS_00500) | - | 45782..46093 (-) | 312 | WP_086041451.1 | hypothetical protein | - |
| MCCS_RS00245 (MCCS_00510) | - | 46333..47793 (-) | 1461 | WP_086041452.1 | DUF6038 family protein | - |
| MCCS_RS12750 (MCCS_00520) | - | 48055..48978 (+) | 924 | WP_226997638.1 | SEFIR domain-containing protein | - |
| MCCS_RS00260 (MCCS_00530) | - | 49258..49752 (+) | 495 | WP_086041453.1 | phosphoribosylanthranilate isomerase | - |
Sequence
Protein
Download Length: 542 a.a. Molecular weight: 61970.95 Da Isoelectric Point: 9.6558
>NTDB_id=228012 MCCS_RS00220 WP_086041447.1 39914..41542(-) (ccrB) [Macrococcoides canis strain KM 45013]
MTKKRAAIYTRVSSALQRDNFSIAGQKKLLEEVCQRNGWEIYEVYTDNGLTGKNMNRPALLKMNEDAKNRKFDIILIYRL
NRLARNTKHVIDMVDFYNKYNVEVYSDTERFDTSTASGRLMLQILASMAEYERSHILENFSAGLVSRAESGYYNGGQVLG
YQQVPGNKRMLAIVEQEALIVKRIFDEYASGKGYRAIANALNKDGYRTKKNNPFDTNSVKYILTNIVYIGKIRYLRYTGW
NEKRRRGFNPNPIIADGKHTPIIDQDLWDKVQTRMKKASKNPMVNGKGENLLTGIIRCPKCGAAHAASNTTNTLKSGEKK
RIRYYSCSQFRNKGASVCSANSIRADVAEAYVFNRIKEVIFNDKVLQQVLENVNSSLEAKPTEMKQRVLNKKQQLEETQV
KLNNLNIALSTSPDLIHTLKGTIDEYASTIEALKATIAEMEAHKEDDIKQLTIEEIKPLLQAIFKDMDRLDKKQLKALYL
SVVDAIHFKKCNEPGKKHDFFITLKINEDVLKEVYNGIEPEEALLSASSDLFTEHETYYLRI
MTKKRAAIYTRVSSALQRDNFSIAGQKKLLEEVCQRNGWEIYEVYTDNGLTGKNMNRPALLKMNEDAKNRKFDIILIYRL
NRLARNTKHVIDMVDFYNKYNVEVYSDTERFDTSTASGRLMLQILASMAEYERSHILENFSAGLVSRAESGYYNGGQVLG
YQQVPGNKRMLAIVEQEALIVKRIFDEYASGKGYRAIANALNKDGYRTKKNNPFDTNSVKYILTNIVYIGKIRYLRYTGW
NEKRRRGFNPNPIIADGKHTPIIDQDLWDKVQTRMKKASKNPMVNGKGENLLTGIIRCPKCGAAHAASNTTNTLKSGEKK
RIRYYSCSQFRNKGASVCSANSIRADVAEAYVFNRIKEVIFNDKVLQQVLENVNSSLEAKPTEMKQRVLNKKQQLEETQV
KLNNLNIALSTSPDLIHTLKGTIDEYASTIEALKATIAEMEAHKEDDIKQLTIEEIKPLLQAIFKDMDRLDKKQLKALYL
SVVDAIHFKKCNEPGKKHDFFITLKINEDVLKEVYNGIEPEEALLSASSDLFTEHETYYLRI
Nucleotide
Download Length: 1629 bp
>NTDB_id=228012 MCCS_RS00220 WP_086041447.1 39914..41542(-) (ccrB) [Macrococcoides canis strain KM 45013]
ATGACTAAGAAAAGAGCTGCTATTTACACAAGGGTATCAAGTGCATTACAACGTGATAACTTCTCAATTGCAGGACAAAA
GAAGTTACTGGAAGAGGTATGCCAAAGAAACGGTTGGGAAATATACGAGGTCTACACGGACAACGGTTTAACTGGGAAGA
ACATGAACAGACCAGCTTTATTAAAAATGAACGAAGATGCTAAGAATAGAAAATTCGATATTATCTTAATCTACAGACTT
AATCGTCTTGCTCGTAATACCAAGCATGTGATTGATATGGTGGACTTCTACAACAAATACAACGTTGAGGTCTATAGCGA
TACGGAAAGGTTCGATACAAGCACAGCCTCAGGTCGATTGATGCTCCAAATACTAGCGTCTATGGCGGAGTATGAAAGGA
GCCACATTTTGGAAAATTTTTCCGCTGGATTAGTGTCTAGAGCTGAATCCGGCTATTACAATGGTGGACAGGTGCTTGGA
TACCAACAAGTGCCTGGAAACAAAAGAATGCTCGCAATCGTCGAACAAGAAGCGCTAATTGTAAAACGTATCTTTGATGA
ATATGCTTCCGGAAAAGGATACAGAGCCATTGCAAATGCATTAAATAAGGACGGCTATCGTACTAAGAAAAATAACCCCT
TCGACACCAATTCCGTTAAATACATCTTAACCAATATCGTTTACATCGGTAAGATAAGATATCTAAGATATACCGGATGG
AATGAAAAGAGACGTCGTGGTTTTAACCCTAATCCTATTATCGCAGACGGCAAGCATACTCCAATTATTGATCAAGACTT
ATGGGATAAAGTACAGACCAGAATGAAAAAAGCGAGTAAGAATCCAATGGTTAACGGTAAAGGCGAAAACCTCTTAACTG
GAATTATACGTTGTCCTAAGTGCGGAGCTGCTCATGCAGCAAGTAATACGACCAATACCCTTAAATCTGGTGAGAAGAAG
CGTATACGCTATTATAGTTGTTCCCAGTTTAGAAATAAAGGTGCATCTGTATGTAGCGCAAACTCAATACGTGCAGATGT
TGCTGAAGCCTATGTCTTCAATCGTATAAAGGAAGTGATATTCAACGATAAAGTACTTCAACAGGTTTTGGAGAATGTCA
ACAGTAGCTTAGAAGCTAAACCAACGGAAATGAAACAAAGAGTGTTGAATAAGAAACAGCAGCTTGAAGAAACACAAGTC
AAACTTAATAACCTTAATATCGCATTATCAACATCCCCTGACCTTATCCATACACTAAAAGGAACTATCGATGAATATGC
GAGTACTATTGAAGCACTTAAGGCGACAATAGCTGAAATGGAAGCGCATAAGGAGGATGACATTAAACAGTTAACGATTG
AGGAGATTAAACCCCTTCTTCAAGCAATATTCAAGGATATGGACCGATTAGATAAGAAACAATTAAAAGCGTTGTATCTC
TCTGTCGTTGATGCAATTCACTTCAAGAAGTGCAATGAGCCAGGAAAGAAACATGACTTCTTCATTACGTTAAAGATCAA
TGAAGATGTTCTTAAAGAAGTATATAACGGTATCGAACCAGAGGAAGCACTGCTTAGTGCTTCCTCTGATTTATTTACAG
AGCATGAAACATACTACCTTCGCATATAG
ATGACTAAGAAAAGAGCTGCTATTTACACAAGGGTATCAAGTGCATTACAACGTGATAACTTCTCAATTGCAGGACAAAA
GAAGTTACTGGAAGAGGTATGCCAAAGAAACGGTTGGGAAATATACGAGGTCTACACGGACAACGGTTTAACTGGGAAGA
ACATGAACAGACCAGCTTTATTAAAAATGAACGAAGATGCTAAGAATAGAAAATTCGATATTATCTTAATCTACAGACTT
AATCGTCTTGCTCGTAATACCAAGCATGTGATTGATATGGTGGACTTCTACAACAAATACAACGTTGAGGTCTATAGCGA
TACGGAAAGGTTCGATACAAGCACAGCCTCAGGTCGATTGATGCTCCAAATACTAGCGTCTATGGCGGAGTATGAAAGGA
GCCACATTTTGGAAAATTTTTCCGCTGGATTAGTGTCTAGAGCTGAATCCGGCTATTACAATGGTGGACAGGTGCTTGGA
TACCAACAAGTGCCTGGAAACAAAAGAATGCTCGCAATCGTCGAACAAGAAGCGCTAATTGTAAAACGTATCTTTGATGA
ATATGCTTCCGGAAAAGGATACAGAGCCATTGCAAATGCATTAAATAAGGACGGCTATCGTACTAAGAAAAATAACCCCT
TCGACACCAATTCCGTTAAATACATCTTAACCAATATCGTTTACATCGGTAAGATAAGATATCTAAGATATACCGGATGG
AATGAAAAGAGACGTCGTGGTTTTAACCCTAATCCTATTATCGCAGACGGCAAGCATACTCCAATTATTGATCAAGACTT
ATGGGATAAAGTACAGACCAGAATGAAAAAAGCGAGTAAGAATCCAATGGTTAACGGTAAAGGCGAAAACCTCTTAACTG
GAATTATACGTTGTCCTAAGTGCGGAGCTGCTCATGCAGCAAGTAATACGACCAATACCCTTAAATCTGGTGAGAAGAAG
CGTATACGCTATTATAGTTGTTCCCAGTTTAGAAATAAAGGTGCATCTGTATGTAGCGCAAACTCAATACGTGCAGATGT
TGCTGAAGCCTATGTCTTCAATCGTATAAAGGAAGTGATATTCAACGATAAAGTACTTCAACAGGTTTTGGAGAATGTCA
ACAGTAGCTTAGAAGCTAAACCAACGGAAATGAAACAAAGAGTGTTGAATAAGAAACAGCAGCTTGAAGAAACACAAGTC
AAACTTAATAACCTTAATATCGCATTATCAACATCCCCTGACCTTATCCATACACTAAAAGGAACTATCGATGAATATGC
GAGTACTATTGAAGCACTTAAGGCGACAATAGCTGAAATGGAAGCGCATAAGGAGGATGACATTAAACAGTTAACGATTG
AGGAGATTAAACCCCTTCTTCAAGCAATATTCAAGGATATGGACCGATTAGATAAGAAACAATTAAAAGCGTTGTATCTC
TCTGTCGTTGATGCAATTCACTTCAAGAAGTGCAATGAGCCAGGAAAGAAACATGACTTCTTCATTACGTTAAAGATCAA
TGAAGATGTTCTTAAAGAAGTATATAACGGTATCGAACCAGAGGAAGCACTGCTTAGTGCTTCCTCTGATTTATTTACAG
AGCATGAAACATACTACCTTCGCATATAG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrB | Staphylococcus aureus N315 |
48.25 |
100 |
0.483 |