Detailed information    

insolico Bioinformatically predicted

Overview

Name   amiE   Type   Regulator
Locus tag   SPS_RS01280 Genome accession   NC_004606
Coordinates   247120..248190 (+) Length   356 a.a.
NCBI ID   WP_002992231.1    Uniprot ID   A0A5S4TWS5
Organism   Streptococcus pyogenes SSI-1     
Function   internalize XIP (predicted from homology)   
Competence regulation

Genomic Context

Location: 242120..253190
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPS_RS01265 (SPs0221) amiA 242648..244618 (+) 1971 WP_002992224.1 peptide ABC transporter substrate-binding protein Regulator
  SPS_RS01270 (SPs0222) amiC 244683..246185 (+) 1503 WP_011054186.1 ABC transporter permease Regulator
  SPS_RS01275 (SPs0223) amiD 246185..247111 (+) 927 WP_011054187.1 oligopeptide ABC transporter permease OppC Regulator
  SPS_RS01280 (SPs0224) amiE 247120..248190 (+) 1071 WP_002992231.1 ABC transporter ATP-binding protein Regulator
  SPS_RS01285 (SPs0225) amiF 248183..249106 (+) 924 WP_002986000.1 ATP-binding cassette domain-containing protein Regulator
  SPS_RS10665 - 249144..249233 (-) 90 WP_109821088.1 IS3 family transposase -
  SPS_RS10365 - 249254..249499 (-) 246 WP_030126956.1 hypothetical protein -

Sequence

Protein


Download         Length: 356 a.a.        Molecular weight: 39680.74 Da        Isoelectric Point: 5.4774

>NTDB_id=22789 SPS_RS01280 WP_002992231.1 247120..248190(+) (amiE) [Streptococcus pyogenes SSI-1]
MTKENNVILTAKDVVVEFDVRDRVLTAIRNVSLELVEGEVLAFVGESGSGKSVLTKTFTGMLESNGRIANGSIVYRGQEL
TDLKTNKEWAKIRGSKIATIFQDPMTSLSPIKTIGSQITEVIIKHQKVSNAKAKEMALDYMNKVGIPNAKKRFEDYPFEY
SGGMRQRIVIAIALACRPDILICDEPTTALDVTIQAQIVELLKSLQREYHFTIIFITHDLGVVASIADKVAVMYAGEIVE
FGTVEEIFYDPRHPYTWSLLSSLPQLADESGELYAIPGTPPSLYSPIIGDAFALRSEYAMVLDFEKAPPAINVSETHWAK
TWLLHPEAPKVQKPEVIQDLHQKILRKMSQQEEGNV

Nucleotide


Download         Length: 1071 bp        

>NTDB_id=22789 SPS_RS01280 WP_002992231.1 247120..248190(+) (amiE) [Streptococcus pyogenes SSI-1]
ATGACAAAAGAAAATAATGTAATCTTAACTGCCAAAGATGTGGTGGTAGAATTTGATGTGCGTGATCGTGTTTTAACAGC
TATTCGTAACGTCTCACTGGAACTTGTTGAAGGAGAAGTCCTTGCTTTTGTAGGGGAATCAGGCTCAGGTAAATCTGTTT
TAACAAAGACCTTTACAGGGATGTTGGAGTCTAATGGACGCATTGCTAATGGTTCAATTGTCTATCGTGGGCAAGAATTG
ACAGATTTAAAAACAAATAAAGAGTGGGCAAAGATTCGCGGCTCAAAAATCGCAACGATTTTCCAAGACCCAATGACCAG
TCTTAGTCCCATTAAAACTATCGGTAGCCAAATCACAGAAGTGATTATTAAGCACCAAAAAGTAAGTAATGCCAAAGCTA
AAGAAATGGCCCTTGATTACATGAATAAAGTGGGTATCCCAAATGCCAAAAAACGCTTTGAAGATTACCCATTTGAGTAT
TCAGGAGGAATGCGTCAACGTATTGTTATCGCTATTGCTTTAGCTTGTCGCCCAGATATTCTTATCTGTGATGAGCCAAC
AACAGCCCTTGATGTGACTATTCAAGCTCAAATCGTTGAGTTATTGAAGTCGCTTCAACGAGAATATCATTTCACCATTA
TCTTTATTACGCACGATTTAGGTGTTGTGGCAAGCATTGCAGATAAAGTGGCTGTCATGTATGCAGGAGAAATTGTTGAA
TTTGGAACAGTCGAAGAGATTTTCTATGATCCAAGACACCCCTATACATGGAGTTTGCTGTCTAGCTTACCGCAGTTGGC
AGATGAATCTGGTGAACTTTACGCTATTCCAGGAACGCCTCCATCACTTTATTCACCAATTATCGGAGATGCCTTTGCAC
TTCGCTCAGAATATGCTATGGTTTTAGACTTTGAAAAAGCACCTCCGGCGATTAACGTATCTGAGACTCATTGGGCCAAA
ACATGGCTTTTACACCCAGAGGCTCCAAAAGTTCAAAAACCAGAAGTCATTCAAGATTTGCATCAAAAAATCTTAAGGAA
AATGTCACAACAGGAGGAAGGAAATGTCTGA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(29-187)

Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY)

(239-299)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5S4TWS5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  amiE Streptococcus salivarius strain HSISS4

76.667

100

0.775
  amiE Streptococcus thermophilus LMG 18311

75.556

100

0.764
  amiE Streptococcus thermophilus LMD-9

75.556

100

0.764
  oppD Streptococcus mutans UA159

56.677

94.663

0.537

Multiple sequence alignment