Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   SPYM3_RS03585 Genome accession   NC_004070
Coordinates   709872..710348 (+) Length   158 a.a.
NCBI ID   WP_002984880.1    Uniprot ID   A0A0H2UU18
Organism   Streptococcus pyogenes MGAS315     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 704872..715348
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPYM3_RS03560 (SpyM3_0644) - 704913..705701 (+) 789 WP_002984887.1 Nif3-like dinuclear metal center hexameric protein -
  SPYM3_RS03565 (SpyM3_0645) - 705741..706847 (+) 1107 WP_011054398.1 NAD(P)/FAD-dependent oxidoreductase -
  SPYM3_RS03570 (SpyM3_0646) rfbA 706905..707774 (+) 870 WP_010922195.1 glucose-1-phosphate thymidylyltransferase RfbA -
  SPYM3_RS03575 (SpyM3_0647) - 707774..708367 (+) 594 WP_002990099.1 dTDP-4-dehydrorhamnose 3,5-epimerase family protein -
  SPYM3_RS03580 (SpyM3_0648) rfbB 708611..709651 (+) 1041 WP_002984881.1 dTDP-glucose 4,6-dehydratase -
  SPYM3_RS03585 (SpyM3_0649) mutX 709872..710348 (+) 477 WP_002984880.1 NUDIX hydrolase Machinery gene
  SPYM3_RS03590 (SpyM3_0650) - 710406..711587 (+) 1182 WP_002990002.1 AI-2E family transporter -
  SPYM3_RS03595 (SpyM3_0651) - 711577..712824 (+) 1248 WP_011054399.1 tetratricopeptide repeat protein -
  SPYM3_RS03600 (SpyM3_0652) fbp54 712883..714535 (-) 1653 WP_011054400.1 Rqc2 family fibronectin-binding protein Fbp54 -

Sequence

Protein


Download         Length: 158 a.a.        Molecular weight: 18462.68 Da        Isoelectric Point: 4.3268

>NTDB_id=22785 SPYM3_RS03585 WP_002984880.1 709872..710348(+) (mutX) [Streptococcus pyogenes MGAS315]
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECARREILEETHLTVTEMAFKGIITFPEFTPGH
DWYTYVFKVTGFEGDLISDEESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY

Nucleotide


Download         Length: 477 bp        

>NTDB_id=22785 SPYM3_RS03585 WP_002984880.1 709872..710348(+) (mutX) [Streptococcus pyogenes MGAS315]
ATGACTCAATTAGCAACCATTTGTTACATTGATAATGGCGATTCTTTGCTATTATTACACCGCAATAAAAAAGAAAATGA
TGTCCACAAAGGCAAGTGGATTTCAGTTGGGGGTAAGCTCGAGGCTGGTGAGACCCCAGATGAGTGTGCCCGTCGTGAGA
TTTTAGAGGAAACCCATTTGACTGTTACAGAGATGGCCTTTAAAGGAATCATTACTTTTCCAGAATTTACCCCTGGTCAT
GACTGGTATACCTATGTTTTTAAAGTAACAGGATTTGAAGGAGACCTCATTTCCGATGAAGAGTCACGAGAAGGAACCTT
GGAATGGGTACCTTACGATCAAGTGTTGGAAAAGCCAACTTGGGAAGGTGATTATGACATTTTTAAATGGATTTTAGAAG
ACCGTCCTTTTTTCTCTGCCAAATTTACCTATGACCAAAACAACCAACTCATGGATAAATCTGTGACCTTTTATTGA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UU18

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

70.253

100

0.703

Multiple sequence alignment