Detailed information NTG0227684

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: C4E16_RS00990
• Genome accession: NZ_CP026647
• Coordinates: 220918..223491 (+)
• Length: 857 a.a.
• NCBI ID: WP_001235051.1
• Uniprot ID: Q9KU18
• Organism: Vibrio cholerae O1 biovar El Tor strain HC1037
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 215918..228491

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C4E16_RS00965 (C4E16_00965)	pheA	216071..217246 (-)	1176	WP_000130282.1	prephenate dehydratase	-
C4E16_RS00970 (C4E16_00970)	hpf	217486..217812 (-)	327	WP_000700176.1	ribosome hibernation-promoting factor, HPF/YfiA family	-
C4E16_RS00975 (C4E16_00975)	comL	218214..218939 (-)	726	WP_000877198.1	outer membrane protein assembly factor BamD	Machinery gene
C4E16_RS00980 (C4E16_00980)	rluD	219094..220068 (+)	975	WP_000941107.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
C4E16_RS00985 (C4E16_00985)	pgeF	220071..220793 (+)	723	WP_000602844.1	peptidoglycan editing factor PgeF	-
C4E16_RS00990 (C4E16_00990)	clpC	220918..223491 (+)	2574	WP_001235051.1	ATP-dependent chaperone ClpB	Regulator

Sequence

Protein

• Length: 857 a.a.
• Molecular weight: 95827.76 Da
• Isoelectric Point: 5.3574

>NTDB_id=227684 C4E16_RS00990 WP_001235051.1 220918..223491(+) (clpC) [Vibrio cholerae O1 biovar El Tor strain HC1037]
MRLDRFTSKFQIAISDAQSLALGRDHQYIEPVHLMVALLDQNGSPIRPLLTMLNVDVMQLRSKLGEMLDRLPKVSGIGGD
VQLSSALGSLFNLCDKVAQKRQDAYISSEIYLLAAIEDKGPLGHLLKEFGLTEKKVSEAIEKIRGGQKVNDPNAEELRQA
LEKFTIDLTERAEQGKLDPVIGRDDEIRRTIQVLQRRTKNNPVIIGEPGVGKTAIVEGLAQRIINNEVPEGLRGRRVLSL
DMGALVAGAKYRGEFEERLKSVLNELAKEEGNIILFIDELHTMVGAGKGEGSMDAGNMLKPALARGELHCVGATTLDEYR
QYIEKDPALERRFQKVLVDEPTVEDTIAILRGLKERYELHHHVEITDPAIVAAASLSHRYISDRQLPDKAIDLIDEAASS
IRMQIDSKPEALDKLERKIIQLKIEQQALSNEHDEASEKRLAILNEELQEKERDYAELEEVWKAEKAALSGTQHIKAALE
QARMDLEVARRAGDLNRMSELQYGRIPELEKQLDLAAQAEMQEMTLLRNKVTDAEIAEVLSKQTGIPVSKMLEAEKEKLL
RMEDVLHKRVIGQKEAVEVVANAIRRSRAGLSDPNRPIGSFLFLGPTGVGKTELCKTLANFLFDSEDAMVRVDMSEFMEK
HSVARLVGAPPGYVGYEEGGYLTEAVRRKPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNL
GSSRIQENFARLDYQGIKEQVMDVVSKHFRPEFLNRVDESVVFHPLGQEHIKSIASIQLARLRQRLAERDYQLEVDDEAL
DLIAHVGFDPVYGARPLKRAIQQNVENPLAKSILAGKFLPGSPILLSVKDGNIFASQ

Nucleotide

• Length: 2574 bp

>NTDB_id=227684 C4E16_RS00990 WP_001235051.1 220918..223491(+) (clpC) [Vibrio cholerae O1 biovar El Tor strain HC1037]
ATGCGTCTTGACAGATTTACGAGCAAATTTCAGATCGCGATTTCCGATGCCCAGTCATTAGCGCTCGGCCGTGATCATCA
ATATATCGAACCTGTGCACCTGATGGTGGCTCTGCTGGATCAAAACGGCAGCCCGATCCGCCCATTACTCACCATGCTTA
ATGTGGATGTGATGCAACTGCGCTCCAAACTTGGCGAAATGCTCGATCGTTTACCCAAAGTCAGTGGTATTGGTGGTGAT
GTACAGCTCTCTTCGGCGCTTGGCTCGCTGTTTAATCTGTGTGATAAGGTTGCGCAAAAGCGTCAAGATGCCTACATCTC
CTCTGAAATCTATCTACTTGCTGCGATTGAGGACAAAGGGCCACTGGGTCACTTACTCAAAGAGTTTGGACTGACCGAGA
AAAAAGTCTCTGAAGCAATAGAGAAGATTCGTGGTGGACAAAAGGTTAATGACCCGAATGCGGAAGAGCTGCGTCAAGCG
TTGGAAAAATTCACCATCGATCTGACTGAACGCGCTGAGCAGGGCAAACTCGATCCTGTGATCGGTCGTGATGATGAAAT
TCGCCGCACCATTCAAGTGCTGCAACGCCGTACCAAGAACAATCCGGTGATCATCGGTGAACCCGGTGTGGGTAAAACTG
CGATTGTGGAAGGCTTGGCGCAGCGCATCATTAATAATGAAGTACCAGAAGGCCTGCGTGGACGGCGAGTGTTGTCTTTA
GATATGGGCGCGCTAGTGGCAGGGGCGAAATACCGCGGCGAATTTGAAGAGCGCTTGAAATCAGTACTCAATGAGCTAGC
GAAAGAAGAAGGCAATATCATCCTCTTCATTGATGAGCTGCACACCATGGTTGGTGCGGGGAAAGGCGAAGGCTCGATGG
ATGCCGGCAACATGCTCAAACCCGCTTTGGCGCGTGGAGAATTGCACTGTGTCGGCGCAACCACTTTAGATGAGTACCGC
CAATACATCGAAAAAGATCCAGCGTTAGAGCGCCGCTTCCAAAAAGTGTTGGTGGATGAGCCCACGGTGGAAGATACCAT
CGCCATCTTGCGTGGATTGAAAGAGCGTTATGAACTGCATCACCATGTCGAAATCACAGATCCAGCGATTGTGGCGGCAG
CGAGCCTATCGCATCGCTATATTTCCGATCGCCAGTTGCCTGATAAAGCGATCGATTTGATCGATGAAGCGGCTTCAAGC
ATCCGGATGCAGATTGACTCCAAACCAGAAGCTCTGGATAAGCTTGAGCGCAAAATCATCCAACTGAAAATCGAGCAGCA
AGCGCTCTCTAATGAGCACGATGAAGCCAGTGAAAAACGCTTGGCGATCTTAAATGAAGAGCTGCAAGAGAAAGAGCGTG
ATTACGCGGAGTTGGAAGAAGTGTGGAAAGCTGAAAAGGCGGCACTCTCCGGCACGCAACATATTAAAGCGGCACTTGAA
CAAGCGCGGATGGATCTGGAAGTCGCTCGCCGTGCGGGGGATTTGAACCGCATGTCAGAGCTGCAATATGGTCGCATTCC
AGAGCTAGAAAAGCAGCTTGATCTGGCTGCGCAAGCCGAAATGCAGGAAATGACTCTGCTACGTAATAAAGTGACGGATG
CAGAAATTGCCGAAGTGCTTTCAAAACAGACTGGCATTCCAGTATCAAAAATGCTCGAAGCTGAGAAAGAAAAGTTGCTG
CGCATGGAAGACGTGCTGCATAAACGCGTGATTGGTCAAAAAGAAGCGGTGGAAGTGGTCGCGAATGCGATCCGCCGCAG
TCGCGCAGGGCTTTCTGATCCAAATCGTCCGATTGGCTCCTTCTTATTCTTGGGGCCAACAGGGGTCGGTAAAACCGAGC
TGTGTAAAACCTTGGCTAACTTCCTGTTTGACAGTGAAGATGCCATGGTACGTGTGGATATGTCGGAATTTATGGAGAAA
CACTCGGTTGCTCGTTTAGTCGGTGCGCCTCCAGGTTATGTCGGCTATGAAGAAGGTGGCTACTTAACGGAAGCTGTACG
CCGTAAACCTTACTCGGTGATTTTGCTCGATGAAGTGGAAAAGGCGCACCCAGATGTCTTCAATATTCTGCTGCAAGTCT
TGGATGATGGCCGCTTGACGGACGGACAAGGGCGCACGGTCGATTTTCGAAATACCGTTGTGATCATGACCTCCAACTTG
GGTTCAAGCCGTATCCAAGAAAATTTTGCAAGGTTGGATTATCAAGGTATCAAAGAACAAGTGATGGACGTAGTCAGCAA
ACACTTCCGTCCTGAGTTCTTGAACCGAGTGGATGAAAGTGTGGTATTCCACCCATTAGGACAAGAGCATATCAAGTCGA
TCGCTTCTATTCAGTTGGCCCGCCTACGTCAACGTTTGGCAGAGCGAGATTACCAACTAGAGGTTGATGATGAGGCGCTG
GATCTGATTGCTCATGTCGGCTTCGATCCGGTTTATGGTGCTCGTCCACTGAAACGCGCGATTCAACAAAATGTGGAAAA
CCCACTGGCCAAATCGATTCTGGCTGGTAAGTTCCTGCCTGGTTCACCTATTTTACTATCGGTAAAAGACGGGAATATTT
TCGCAAGCCAGTAG

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (596-759)

• AAA lid domain (AAA_lid_9) (342-442)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (766-843)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-68)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (94-145)

• ATPase family associated with various cellular activities (AAA) (AAA) (204-335)

3D structure

• AlphaFold DB: Q9KU18

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	47.569	100	0.48
clpC	Lactococcus lactis subsp. cremoris KW2	47.33	80.863	0.383