Detailed information NTG0227520

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: B9T46_RS15265
• Genome accession: NZ_CP020960
• Coordinates: 2851275..2852162 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain JK3137
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2846275..2857162

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
B9T46_RS15230 (B9T46_15230)	-	2846294..2846386 (+)	93	WP_010956583.1	hypothetical protein	-
B9T46_RS15235 (B9T46_15235)	-	2846494..2846991 (-)	498	WP_001065268.1	glutathione peroxidase	-
B9T46_RS15240 (B9T46_15240)	-	2847001..2847261 (-)	261	WP_001789910.1	hypothetical protein	-
B9T46_RS15250 (B9T46_15250)	-	2847643..2847756 (-)	114	WP_001791776.1	hypothetical protein	-
B9T46_RS15255 (B9T46_15255)	-	2848415..2850415 (-)	2001	WP_000776751.1	ABC transporter permease	-
B9T46_RS15260 (B9T46_15260)	-	2850412..2851167 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
B9T46_RS15265 (B9T46_15265)	braS	2851275..2852162 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
B9T46_RS15270 (B9T46_15270)	braR	2852173..2852838 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
B9T46_RS15275 (B9T46_15275)	-	2852864..2853064 (-)	201	WP_000604728.1	hypothetical protein	-
B9T46_RS15280 (B9T46_15280)	-	2853262..2854686 (+)	1425	WP_000953744.1	alkaline phosphatase	-
B9T46_RS15845	-	2854756..2854866 (+)	111	WP_001791296.1	hypothetical protein	-
B9T46_RS15290 (B9T46_15290)	-	2854969..2855424 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
B9T46_RS15295 (B9T46_15295)	-	2855669..2856430 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=227520 B9T46_RS15265 WP_000143419.1 2851275..2852162(-) (braS) [Staphylococcus aureus strain JK3137]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=227520 B9T46_RS15265 WP_000143419.1 2851275..2852162(-) (braS) [Staphylococcus aureus strain JK3137]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997