Detailed information NTG0227478

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: B9T45_RS13885
• Genome accession: NZ_CP020959
• Coordinates: 2654567..2655454 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain H489
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2649567..2660454

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
B9T45_RS13850 (B9T45_13850)	-	2649586..2649678 (+)	93	WP_010956583.1	hypothetical protein	-
B9T45_RS13855 (B9T45_13855)	-	2649786..2650283 (-)	498	WP_001065268.1	glutathione peroxidase	-
B9T45_RS13860 (B9T45_13860)	-	2650293..2650553 (-)	261	WP_001789910.1	hypothetical protein	-
B9T45_RS13870 (B9T45_13870)	-	2650935..2651048 (-)	114	WP_011447078.1	hypothetical protein	-
B9T45_RS13875 (B9T45_13875)	-	2651707..2653707 (-)	2001	WP_000776751.1	ABC transporter permease	-
B9T45_RS13880 (B9T45_13880)	-	2653704..2654459 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
B9T45_RS13885 (B9T45_13885)	braS	2654567..2655454 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
B9T45_RS13890 (B9T45_13890)	braR	2655465..2656130 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
B9T45_RS13895 (B9T45_13895)	-	2656156..2656356 (-)	201	WP_000604728.1	hypothetical protein	-
B9T45_RS13900 (B9T45_13900)	-	2656554..2657978 (+)	1425	WP_000953744.1	alkaline phosphatase	-
B9T45_RS14420	-	2658048..2658158 (+)	111	WP_001791296.1	hypothetical protein	-
B9T45_RS13910 (B9T45_13910)	-	2658261..2658716 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
B9T45_RS13915 (B9T45_13915)	-	2658961..2659722 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=227478 B9T45_RS13885 WP_000143419.1 2654567..2655454(-) (braS) [Staphylococcus aureus strain H489]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=227478 B9T45_RS13885 WP_000143419.1 2654567..2655454(-) (braS) [Staphylococcus aureus strain H489]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997