Detailed information NTG0227437

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: B9T42_RS14135
• Genome accession: NZ_CP020957
• Coordinates: 2692197..2693084 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain C3948
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2687197..2698084

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
B9T42_RS14100 (B9T42_14100)	-	2687216..2687308 (+)	93	WP_010956583.1	hypothetical protein	-
B9T42_RS14105 (B9T42_14105)	-	2687416..2687913 (-)	498	WP_001065268.1	glutathione peroxidase	-
B9T42_RS14110 (B9T42_14110)	-	2687923..2688183 (-)	261	WP_001789910.1	hypothetical protein	-
B9T42_RS14120 (B9T42_14120)	-	2688565..2688678 (-)	114	WP_011447078.1	hypothetical protein	-
B9T42_RS14125 (B9T42_14125)	-	2689337..2691337 (-)	2001	WP_000776751.1	ABC transporter permease	-
B9T42_RS14130 (B9T42_14130)	-	2691334..2692089 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
B9T42_RS14135 (B9T42_14135)	braS	2692197..2693084 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
B9T42_RS14140 (B9T42_14140)	braR	2693095..2693760 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
B9T42_RS14145 (B9T42_14145)	-	2693786..2693986 (-)	201	WP_000604728.1	hypothetical protein	-
B9T42_RS14150 (B9T42_14150)	-	2694184..2695608 (+)	1425	WP_000953744.1	alkaline phosphatase	-
B9T42_RS14660	-	2695678..2695788 (+)	111	WP_001791296.1	hypothetical protein	-
B9T42_RS14160 (B9T42_14160)	-	2695891..2696346 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
B9T42_RS14165 (B9T42_14165)	-	2696591..2697352 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=227437 B9T42_RS14135 WP_000143419.1 2692197..2693084(-) (braS) [Staphylococcus aureus strain C3948]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=227437 B9T42_RS14135 WP_000143419.1 2692197..2693084(-) (braS) [Staphylococcus aureus strain C3948]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997