Detailed information NTG0227432

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: B9T42_RS10030
• Genome accession: NZ_CP020957
• Coordinates: 1949270..1950313 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain C3948
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1944270..1955313

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
B9T42_RS10000 (B9T42_10000)	-	1944688..1945944 (-)	1257	WP_129940475.1	aminopeptidase	-
B9T42_RS10005 (B9T42_10005)	-	1945947..1946147 (-)	201	WP_000180461.1	DUF1128 family protein	-
B9T42_RS10010 (B9T42_10010)	-	1946294..1946758 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
B9T42_RS10015 (B9T42_10015)	-	1946765..1947040 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
B9T42_RS10020 (B9T42_10020)	-	1947318..1948535 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
B9T42_RS10025 (B9T42_10025)	vraR	1948651..1949280 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
B9T42_RS10030 (B9T42_10030)	vraS	1949270..1950313 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
B9T42_RS10035 (B9T42_10035)	liaF	1950310..1951011 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
B9T42_RS10040 (B9T42_10040)	-	1951026..1951412 (-)	387	WP_001110179.1	hypothetical protein	-
B9T42_RS10045 (B9T42_10045)	map	1951629..1952387 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
B9T42_RS10055 (B9T42_10055)	-	1952974..1953960 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
B9T42_RS10070 (B9T42_10070)	-	1954450..1954863 (-)	414	WP_001549145.1	hypothetical protein	-
B9T42_RS10075 (B9T42_10075)	-	1954892..1955002 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=227432 B9T42_RS10030 WP_001017131.1 1949270..1950313(-) (vraS) [Staphylococcus aureus strain C3948]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=227432 B9T42_RS10030 WP_001017131.1 1949270..1950313(-) (vraS) [Staphylococcus aureus strain C3948]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1