Detailed information
Bioinformatically predicted
Overview
| Name | ccrA | Type | Machinery gene |
| Locus tag | B9T41_RS00225 | Genome accession | NZ_CP020956 |
| Coordinates | 48213..49562 (-) | Length | 449 a.a. |
| NCBI ID | WP_048519614.1 | Uniprot ID | Q8VUU8 |
| Organism | Staphylococcus aureus strain C8879 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| SCCmec | 39798..97313 | 48213..49562 | within | 0 |
Gene organization within MGE regions
Location: 39798..97313
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| B9T41_RS00180 (B9T41_00180) | mecA | 39798..41807 (-) | 2010 | WP_001801873.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
| B9T41_RS00185 (B9T41_00185) | - | 41904..42890 (+) | 987 | WP_001549960.1 | beta-lactam sensor/signal transducer MecR1 | - |
| B9T41_RS00190 (B9T41_00190) | - | 42862..43122 (+) | 261 | WP_001549961.1 | type I restriction enzyme endonuclease domain-containing protein | - |
| B9T41_RS00195 (B9T41_00195) | - | 43113..44720 (-) | 1608 | Protein_33 | IS1182 family transposase | - |
| B9T41_RS00200 (B9T41_00200) | - | 44772..45278 (-) | 507 | WP_001092189.1 | DUF1643 domain-containing protein | - |
| B9T41_RS00205 (B9T41_00205) | - | 45293..45604 (-) | 312 | WP_000700851.1 | DUF960 family protein | - |
| B9T41_RS00215 (B9T41_00215) | - | 45691..46041 (-) | 351 | WP_000849672.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| B9T41_RS00220 (B9T41_00220) | ccrB | 46563..48191 (-) | 1629 | WP_048519615.1 | recombinase family protein | Machinery gene |
| B9T41_RS00225 (B9T41_00225) | ccrA | 48213..49562 (-) | 1350 | WP_048519614.1 | recombinase family protein | Machinery gene |
| B9T41_RS00230 (B9T41_00230) | - | 49796..51586 (-) | 1791 | WP_001063506.1 | DUF927 domain-containing protein | - |
| B9T41_RS00235 (B9T41_00235) | - | 51706..53136 (-) | 1431 | WP_001008607.1 | DUF6038 family protein | - |
| B9T41_RS00240 (B9T41_00240) | - | 53253..54023 (+) | 771 | WP_000767841.1 | DUF6414 family protein | - |
| B9T41_RS00245 (B9T41_00245) | - | 54007..55122 (+) | 1116 | WP_000121739.1 | AAA family ATPase | - |
| B9T41_RS00250 (B9T41_00250) | - | 55370..55504 (-) | 135 | WP_001790628.1 | hypothetical protein | - |
| B9T41_RS00255 (B9T41_00255) | - | 55468..55560 (+) | 93 | WP_001790000.1 | hypothetical protein | - |
| B9T41_RS00260 (B9T41_00260) | - | 55707..57454 (+) | 1748 | Protein_45 | DUF6119 family protein | - |
| B9T41_RS00265 (B9T41_00265) | - | 57548..58000 (-) | 453 | Protein_46 | tRNA-dihydrouridine synthase | - |
| B9T41_RS00270 (B9T41_00270) | - | 58016..58117 (-) | 102 | WP_001791873.1 | hypothetical protein | - |
| B9T41_RS00275 (B9T41_00275) | - | 58215..58970 (-) | 756 | WP_000355845.1 | sulfite exporter TauE/SafE family protein | - |
| B9T41_RS00280 (B9T41_00280) | cstR | 58970..59230 (-) | 261 | WP_001105087.1 | persulfide-sensing transcriptional repressor CstR | - |
| B9T41_RS00285 (B9T41_00285) | cstA | 59367..60434 (+) | 1068 | WP_000816129.1 | persulfide response sulfurtransferase CstA | - |
| B9T41_RS00290 (B9T41_00290) | cstB | 60465..61799 (+) | 1335 | WP_000465472.1 | persulfide dioxygenase-sulfurtransferase CstB | - |
| B9T41_RS14915 | sqr | 61818..63011 (+) | 1194 | Protein_52 | type II sulfide:quinone oxidoreductase Sqr | - |
| B9T41_RS15060 | - | 63278..63492 (-) | 215 | Protein_53 | universal stress protein | - |
| B9T41_RS00315 (B9T41_00315) | - | 63678..64664 (-) | 987 | WP_000662031.1 | tRNA-dihydrouridine synthase | - |
| B9T41_RS00320 (B9T41_00320) | - | 64973..65176 (+) | 204 | WP_000398679.1 | DUF6007 family protein | - |
| B9T41_RS00325 (B9T41_00325) | - | 65225..65521 (+) | 297 | WP_000201640.1 | TfoX/Sxy family protein | - |
| B9T41_RS00330 (B9T41_00330) | - | 65593..66813 (-) | 1221 | WP_000130765.1 | MFS transporter | - |
| B9T41_RS00335 (B9T41_00335) | - | 66806..67356 (-) | 551 | Protein_58 | flavodoxin family protein | - |
| B9T41_RS00340 (B9T41_00340) | - | 67469..68329 (+) | 861 | WP_001052510.1 | LysR family transcriptional regulator | - |
| B9T41_RS00345 (B9T41_00345) | - | 68684..69217 (-) | 534 | WP_000543163.1 | DUF4865 family protein | - |
| B9T41_RS00350 (B9T41_00350) | - | 69308..70051 (+) | 744 | WP_001793250.1 | LysR family transcriptional regulator | - |
| B9T41_RS00355 (B9T41_00355) | - | 70485..71087 (+) | 603 | WP_000908952.1 | hypothetical protein | - |
| B9T41_RS00360 (B9T41_00360) | - | 71354..74506 (+) | 3153 | WP_000080557.1 | DEAD/DEAH box helicase | - |
| B9T41_RS00365 (B9T41_00365) | - | 74563..75045 (+) | 483 | WP_000410568.1 | hypothetical protein | - |
| B9T41_RS00370 (B9T41_00370) | - | 75250..76236 (+) | 987 | WP_000710576.1 | phosphatidylinositol-specific phospholipase C | - |
| B9T41_RS00375 (B9T41_00375) | - | 76457..77227 (+) | 771 | WP_000977774.1 | tandem-type lipoprotein | - |
| B9T41_RS00380 (B9T41_00380) | - | 77279..78049 (+) | 771 | WP_000597212.1 | tandem-type lipoprotein | - |
| B9T41_RS00385 (B9T41_00385) | - | 78113..78883 (+) | 771 | WP_000977781.1 | tandem-type lipoprotein | - |
| B9T41_RS00390 (B9T41_00390) | - | 78950..79717 (+) | 768 | WP_000826311.1 | tandem-type lipoprotein | - |
| B9T41_RS00395 (B9T41_00395) | - | 79811..82048 (+) | 2238 | WP_001188495.1 | helix-turn-helix domain-containing protein | - |
| B9T41_RS00400 (B9T41_00400) | - | 82199..83377 (+) | 1179 | WP_001075826.1 | M20 family metallopeptidase | - |
| B9T41_RS00405 (B9T41_00405) | norC | 83379..84767 (+) | 1389 | WP_001006445.1 | multidrug efflux MFS transporter NorC | - |
| B9T41_RS00410 (B9T41_00410) | - | 85260..86921 (-) | 1662 | WP_001791835.1 | Na/Pi cotransporter family protein | - |
| B9T41_RS00415 (B9T41_00415) | - | 87247..89022 (-) | 1776 | WP_000291842.1 | oleate hydratase | - |
| B9T41_RS00420 (B9T41_00420) | - | 89196..90068 (-) | 873 | WP_001038103.1 | DMT family transporter | - |
| B9T41_RS00425 (B9T41_00425) | - | 90181..91578 (+) | 1398 | WP_001151814.1 | PLP-dependent aminotransferase family protein | - |
| B9T41_RS00430 (B9T41_00430) | - | 91768..92241 (+) | 474 | WP_000036327.1 | DUF1648 domain-containing protein | - |
| B9T41_RS00435 (B9T41_00435) | - | 92503..94095 (+) | 1593 | WP_000173902.1 | L-lactate permease | - |
| B9T41_RS00445 (B9T41_00445) | fabI | 94589..95359 (+) | 771 | WP_000609031.1 | enoyl-ACP reductase FabI | - |
Sequence
Protein
Download Length: 449 a.a. Molecular weight: 52541.24 Da Isoelectric Point: 9.9150
>NTDB_id=227362 B9T41_RS00225 WP_048519614.1 48213..49562(-) (ccrA) [Staphylococcus aureus strain C8879]
MKQVIGYLRQSTMKQQSLAAQKQAIEAIAEKHHIQHINFYSDKQSGRKDNRSGYRQMTQLIQQGQCDILCCYRLNRLHRN
LKNALKLIKLCQTYHVHILSVHDGYFDMDQAFDRLKLNIFISLAELESDNIGEQVKNGLQEKAKQGQLITTHAPFGYDYH
NGTFIINQNESPTVKAVFNYYIKGHGYKKIAQLLEEDNTYINRQPYQVRNIIMNPNYCGRVINQYGQFDNMFPSIVSANV
YEQAQRLRLQKQTKQTSSDNQLKQKIKCPCCNATLTNMTIRKKNHTLRYYVCPKNMNASRFVCDFKGINAQTLEDKVLEV
CRDFYQNQRIYTKIKGAIDKRIKRQRNIEKHHILTQEQLIEKLAQGIIDAETFREQTQSLRQQPQRTTSINGHQIQHTIQ
NIIQKRFTLNILYPYIETIHITKDKNLIGIYFKNEPLNIVNQAMQSSIA
MKQVIGYLRQSTMKQQSLAAQKQAIEAIAEKHHIQHINFYSDKQSGRKDNRSGYRQMTQLIQQGQCDILCCYRLNRLHRN
LKNALKLIKLCQTYHVHILSVHDGYFDMDQAFDRLKLNIFISLAELESDNIGEQVKNGLQEKAKQGQLITTHAPFGYDYH
NGTFIINQNESPTVKAVFNYYIKGHGYKKIAQLLEEDNTYINRQPYQVRNIIMNPNYCGRVINQYGQFDNMFPSIVSANV
YEQAQRLRLQKQTKQTSSDNQLKQKIKCPCCNATLTNMTIRKKNHTLRYYVCPKNMNASRFVCDFKGINAQTLEDKVLEV
CRDFYQNQRIYTKIKGAIDKRIKRQRNIEKHHILTQEQLIEKLAQGIIDAETFREQTQSLRQQPQRTTSINGHQIQHTIQ
NIIQKRFTLNILYPYIETIHITKDKNLIGIYFKNEPLNIVNQAMQSSIA
Nucleotide
Download Length: 1350 bp
>NTDB_id=227362 B9T41_RS00225 WP_048519614.1 48213..49562(-) (ccrA) [Staphylococcus aureus strain C8879]
ATGAAACAAGTTATAGGCTATTTACGTCAAAGTACGATGAAACAACAATCTCTTGCAGCACAGAAACAGGCTATCGAAGC
AATAGCCGAAAAACATCATATTCAACATATCAACTTTTATAGCGACAAACAATCAGGACGCAAAGATAATCGTAGTGGGT
ATCGACAAATGACGCAATTAATTCAACAAGGGCAATGTGACATATTATGTTGTTATCGTCTTAATAGATTACATCGTAAT
CTGAAAAATGCATTAAAACTCATCAAATTATGTCAAACTTATCATGTTCATATCTTAAGCGTACATGATGGTTACTTTGA
TATGGATCAAGCTTTCGACCGACTCAAGCTTAATATCTTCATCAGTTTAGCCGAACTTGAATCAGATAATATTGGAGAAC
AAGTCAAAAATGGCCTTCAAGAAAAGGCAAAACAAGGTCAATTGATTACAACACATGCGCCTTTTGGTTACGACTATCAC
AACGGAACATTCATCATCAATCAAAATGAGTCACCAACGGTAAAGGCTGTATTCAATTATTACATTAAAGGCCATGGTTA
TAAGAAAATTGCACAGTTATTAGAAGAAGATAACACGTATATCAATCGACAACCTTATCAAGTTCGTAATATTATCATGA
ACCCTAATTATTGTGGTCGTGTTATCAACCAATACGGTCAATTCGACAATATGTTCCCTTCTATTGTTTCAGCAAATGTA
TATGAACAAGCGCAGAGACTTCGATTGCAAAAACAAACCAAACAGACATCTTCGGATAATCAACTCAAACAAAAAATCAA
ATGCCCATGTTGTAATGCAACACTTACAAATATGACCATTAGAAAAAAGAATCATACATTACGTTACTACGTCTGTCCTA
AAAACATGAATGCTTCACGCTTTGTCTGTGATTTTAAAGGCATCAATGCACAAACACTTGAAGATAAAGTATTAGAAGTG
TGCCGAGACTTTTATCAAAATCAACGCATCTACACAAAAATTAAAGGTGCGATTGACAAACGCATCAAAAGACAAAGAAA
CATAGAAAAACATCACATATTGACTCAAGAACAACTGATAGAAAAGTTGGCACAAGGCATCATTGATGCAGAAACGTTCA
GAGAACAAACGCAATCATTACGTCAACAACCGCAACGCACTACATCTATAAATGGGCATCAAATACAACACACCATTCAA
AATATTATTCAAAAACGTTTCACGTTAAACATATTGTACCCCTATATTGAAACCATTCACATTACGAAAGATAAAAATCT
TATAGGAATCTATTTCAAAAATGAACCACTCAATATCGTCAATCAAGCCATGCAATCATCGATTGCATAA
ATGAAACAAGTTATAGGCTATTTACGTCAAAGTACGATGAAACAACAATCTCTTGCAGCACAGAAACAGGCTATCGAAGC
AATAGCCGAAAAACATCATATTCAACATATCAACTTTTATAGCGACAAACAATCAGGACGCAAAGATAATCGTAGTGGGT
ATCGACAAATGACGCAATTAATTCAACAAGGGCAATGTGACATATTATGTTGTTATCGTCTTAATAGATTACATCGTAAT
CTGAAAAATGCATTAAAACTCATCAAATTATGTCAAACTTATCATGTTCATATCTTAAGCGTACATGATGGTTACTTTGA
TATGGATCAAGCTTTCGACCGACTCAAGCTTAATATCTTCATCAGTTTAGCCGAACTTGAATCAGATAATATTGGAGAAC
AAGTCAAAAATGGCCTTCAAGAAAAGGCAAAACAAGGTCAATTGATTACAACACATGCGCCTTTTGGTTACGACTATCAC
AACGGAACATTCATCATCAATCAAAATGAGTCACCAACGGTAAAGGCTGTATTCAATTATTACATTAAAGGCCATGGTTA
TAAGAAAATTGCACAGTTATTAGAAGAAGATAACACGTATATCAATCGACAACCTTATCAAGTTCGTAATATTATCATGA
ACCCTAATTATTGTGGTCGTGTTATCAACCAATACGGTCAATTCGACAATATGTTCCCTTCTATTGTTTCAGCAAATGTA
TATGAACAAGCGCAGAGACTTCGATTGCAAAAACAAACCAAACAGACATCTTCGGATAATCAACTCAAACAAAAAATCAA
ATGCCCATGTTGTAATGCAACACTTACAAATATGACCATTAGAAAAAAGAATCATACATTACGTTACTACGTCTGTCCTA
AAAACATGAATGCTTCACGCTTTGTCTGTGATTTTAAAGGCATCAATGCACAAACACTTGAAGATAAAGTATTAGAAGTG
TGCCGAGACTTTTATCAAAATCAACGCATCTACACAAAAATTAAAGGTGCGATTGACAAACGCATCAAAAGACAAAGAAA
CATAGAAAAACATCACATATTGACTCAAGAACAACTGATAGAAAAGTTGGCACAAGGCATCATTGATGCAGAAACGTTCA
GAGAACAAACGCAATCATTACGTCAACAACCGCAACGCACTACATCTATAAATGGGCATCAAATACAACACACCATTCAA
AATATTATTCAAAAACGTTTCACGTTAAACATATTGTACCCCTATATTGAAACCATTCACATTACGAAAGATAAAAATCT
TATAGGAATCTATTTCAAAAATGAACCACTCAATATCGTCAATCAAGCCATGCAATCATCGATTGCATAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrA | Staphylococcus aureus N315 |
96.214 |
100 |
0.962 |
| ccrA | Staphylococcus aureus COL |
75.056 |
100 |
0.751 |