Detailed information NTG0226971

Bioinformatically predicted

Overview

• Name: letS
• Type: Regulator
• Locus tag: B0B39_RS06480
• Genome accession: NZ_CP020894
• Coordinates: 1486606..1489341 (-)
• Length: 911 a.a.
• NCBI ID: WP_085956275.1
• Uniprot ID: -
• Organism: Legionella longbeachae strain F1157CHC
• Function: regulate competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1481606..1494341

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
B0B39_RS06450 (B0B39_17810)	-	1481749..1482282 (+)	534	Protein_1276	IS5 family transposase	-
B0B39_RS06460 (B0B39_17815)	-	1482458..1483858 (-)	1401	WP_085662989.1	APC family permease	-
B0B39_RS06465 (B0B39_17820)	-	1484189..1484512 (-)	324	WP_003632054.1	BolA family protein	-
B0B39_RS06470 (B0B39_17825)	pilA2	1484594..1485028 (-)	435	WP_003632053.1	pilin	Machinery gene
B0B39_RS06475 (B0B39_17830)	-	1485321..1486565 (-)	1245	WP_003632052.1	6-phosphofructokinase	-
B0B39_RS06480 (B0B39_17835)	letS	1486606..1489341 (-)	2736	WP_085956275.1	two-component system sensor histidine kinase LetS	Regulator
B0B39_RS06485 (B0B39_17840)	gltX	1489470..1490885 (+)	1416	WP_085662990.1	glutamate--tRNA ligase	-
B0B39_RS06490 (B0B39_17845)	-	1490882..1492156 (+)	1275	WP_085662991.1	serine hydrolase domain-containing protein	-
B0B39_RS06495 (B0B39_17850)	-	1492296..1493279 (+)	984	WP_003632046.1	hypothetical protein	-
B0B39_RS06500 (B0B39_17855)	gstA	1493338..1493940 (+)	603	WP_003632045.1	glutathione transferase GstA	-

Sequence

Protein

• Length: 911 a.a.
• Molecular weight: 102825.48 Da
• Isoelectric Point: 7.7707

>NTDB_id=226971 B0B39_RS06480 WP_085956275.1 1486606..1489341(-) (letS) [Legionella longbeachae strain F1157CHC]
MLKSIGIKYQLRITTLIPVFLVALLLAIFYNGLFGNDLKQHMSRLGEAYIRQLLPAAQYAMLRGDDRTLQGLINASTINP
EVKALAFYSSDGQLLAYRGGKHSLNKPFTAPKFTGDYIKSKQINPFTINFIAPVTIPKFNLYSNSSFKNILSPMASRADD
ILGWLSLDIDTRSMIIKRYQMLIVTIFITLFGLLVGLTIHYFLSKQIYLPISRLRRSMKQILRNEFETEIKTTSSGELGI
IEQGCSHLQKKHLETIRDLNHHIEVATADLQQSLELLEEKNIELSLEKKKIEEKSRQKSEFIANMSHEIRTPMNGVIGFT
NVLLESKLDPLQLDYVKTIKSSAQDLLGIINDILDFSKIDAGKLHLDCIPLNIRHCIDEVLALAAPNAHKKGIDLIPITE
LNVPKIVLGDPFRVKQFISNLVTNAVKFTDHGYVLIRTNVEQETEKDYTLCITITDTGLGISPEDQSKLFTAFNQADTSI
TRRYGGSGLGLVICKKLCEEMKGRITFASELNKGSVFTAYIKVEKLVAYEVERNQVHPFAHFKMLCFDDNPMQLEALCNG
LGYWGIKCIAVSSLNQLAKELKDNKDCQIAFLNINKGYEQQITKLIAEHNYFPYVLISKWLINDYAALGAQGFLYKPISI
QKLQDIIESLTNQENIEKSVNHELEGLREQLRFLHPDLLIAEDNPVNKMLLDSLLGTRSNITSVDNGEIAVSVCNEKKFS
LILLDLRMPKINGLEAARLIRQKSEFNRHTPIVLISANGRDVNDIDLKKAGVNFCLQKPIDEKQLLIQILRIADKAKHSA
IDWQLCIQKASGNQSLAEEFLARFVEELLKNREEFIQLMHEKNVKQLGEVAHKLHGACCFSGVPTLQKKVVQVEKLAAHA
ASIEELAMPFAELIQSIDAVISEYENQKIKT

Nucleotide

• Length: 2736 bp

>NTDB_id=226971 B0B39_RS06480 WP_085956275.1 1486606..1489341(-) (letS) [Legionella longbeachae strain F1157CHC]
ATCTTGAAAAGCATTGGTATAAAGTATCAACTACGAATTACTACTTTAATTCCTGTTTTTCTCGTCGCCCTACTCCTTGC
CATTTTTTATAATGGGTTGTTTGGTAATGACTTAAAACAACACATGTCTCGCCTTGGTGAAGCATATATCCGGCAATTAC
TTCCGGCTGCCCAGTATGCTATGCTGCGTGGGGACGATCGAACCTTACAAGGCCTAATCAATGCCTCTACAATCAACCCC
GAAGTTAAAGCACTTGCTTTTTATAGTAGCGACGGTCAACTCCTTGCTTATCGTGGTGGCAAACATTCGCTTAACAAACC
ATTTACTGCACCTAAATTCACCGGGGATTACATCAAAAGTAAACAAATTAACCCCTTTACTATTAATTTTATCGCGCCGG
TTACGATTCCAAAATTCAATTTGTATTCCAATTCTTCTTTTAAAAATATTTTAAGTCCCATGGCATCCCGTGCTGATGAC
ATTCTTGGGTGGTTGTCTCTTGATATTGATACTCGTTCAATGATAATCAAACGTTATCAGATGCTTATTGTCACTATTTT
CATTACTTTATTTGGGTTATTAGTAGGATTAACCATTCACTACTTTCTCTCCAAACAAATTTATTTACCTATTTCTCGTT
TACGACGAAGCATGAAACAAATTTTGCGTAACGAGTTTGAAACAGAAATAAAAACAACAAGCTCTGGTGAATTAGGCATA
ATTGAACAGGGATGTTCCCATTTGCAAAAAAAACACCTTGAAACGATACGTGATCTAAACCACCACATTGAGGTAGCCAC
GGCTGATTTACAACAAAGTTTGGAACTCTTGGAAGAAAAAAATATTGAACTCTCCCTCGAAAAGAAAAAAATTGAAGAAA
AAAGTCGGCAAAAATCTGAGTTCATAGCCAATATGAGCCATGAAATTCGTACGCCGATGAATGGAGTTATTGGTTTTACT
AACGTTTTGCTTGAAAGTAAACTCGATCCATTACAACTGGATTATGTAAAAACAATTAAATCATCAGCACAAGACTTATT
AGGGATTATCAATGATATTCTCGATTTCTCAAAAATTGATGCAGGAAAACTTCATCTCGATTGTATTCCGTTAAATATTC
GCCATTGTATTGATGAAGTACTCGCTCTTGCAGCACCTAATGCCCATAAGAAGGGAATCGACTTAATTCCTATAACAGAA
CTAAACGTACCTAAAATTGTTTTAGGGGATCCCTTCAGGGTGAAACAATTCATTAGCAACCTGGTAACTAATGCTGTTAA
ATTTACCGATCATGGATATGTATTAATCCGTACCAATGTGGAGCAGGAAACGGAAAAAGATTACACTTTATGCATTACAA
TTACTGATACAGGCCTAGGTATTTCTCCTGAAGACCAAAGCAAATTATTTACAGCCTTCAATCAAGCAGATACAAGTATT
ACCCGTCGTTATGGGGGCTCCGGACTTGGCTTGGTAATTTGCAAAAAACTCTGCGAGGAAATGAAAGGCCGTATTACTTT
CGCCAGCGAACTCAACAAAGGTTCTGTATTTACCGCTTATATCAAGGTTGAAAAATTGGTTGCTTATGAAGTTGAAAGAA
ATCAAGTGCATCCTTTTGCGCATTTCAAAATGCTTTGTTTTGACGATAACCCAATGCAATTGGAAGCCCTGTGTAATGGC
TTAGGATATTGGGGAATAAAATGTATCGCTGTAAGTTCACTCAATCAACTCGCGAAAGAGCTGAAAGACAATAAAGACTG
CCAAATCGCATTTCTTAATATCAATAAAGGCTACGAACAGCAAATTACCAAGCTAATAGCCGAACATAATTATTTTCCCT
ATGTATTAATCTCTAAATGGCTTATCAATGATTATGCAGCACTTGGAGCACAGGGATTTTTATATAAACCCATTAGCATC
CAAAAACTCCAAGATATTATTGAGTCATTAACAAATCAGGAAAATATTGAAAAGTCGGTTAACCATGAATTAGAAGGTTT
AAGGGAACAATTACGTTTCTTACATCCTGATCTTCTTATAGCTGAAGATAATCCAGTAAATAAAATGCTTCTTGATTCTT
TATTAGGGACTCGTTCCAACATTACATCCGTTGATAATGGCGAAATAGCCGTATCGGTGTGTAATGAAAAGAAATTCAGT
CTCATCTTGCTTGATTTGCGTATGCCTAAAATAAATGGCTTGGAAGCTGCTCGACTTATCCGCCAAAAATCAGAGTTTAA
TCGTCATACACCAATAGTATTGATTAGTGCAAATGGTAGAGATGTTAATGATATTGATTTAAAGAAAGCTGGTGTAAATT
TTTGTTTGCAAAAACCTATAGACGAAAAACAATTATTAATTCAAATTTTACGTATTGCAGATAAAGCAAAACACTCAGCA
ATAGATTGGCAACTATGTATTCAAAAAGCCTCAGGAAATCAATCACTTGCTGAAGAGTTTCTTGCTCGGTTTGTAGAAGA
ATTGCTTAAAAATCGTGAAGAGTTTATCCAATTAATGCATGAAAAAAATGTGAAGCAACTGGGCGAAGTGGCGCATAAAC
TTCATGGAGCATGTTGTTTTAGTGGTGTTCCCACGTTACAAAAAAAAGTAGTTCAGGTTGAAAAACTTGCTGCGCATGCT
GCTTCAATCGAAGAGTTAGCTATGCCTTTCGCAGAATTAATTCAAAGCATCGATGCGGTGATTAGTGAATACGAAAATCA
AAAAATAAAAACTTAG

Domains

Predicted by InterproScan.

• Single cache domain 4 (sCache_4) (36-180)

• Hpt domain (Hpt) (819-900)

• His Kinase A (phospho-acceptor) domain (HisKA) (298-362)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (409-524)

• Response regulator receiver domain (Response_reg) (679-787)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
letS	Legionella pneumophila strain ERS1305867	78.06	99.561	0.777