Detailed information NTG0022684

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: LP_RS01770
• Genome accession: NC_004567
• Coordinates: 376436..378586 (+)
• Length: 716 a.a.
• NCBI ID: WP_003641986.1
• Uniprot ID: A0AAW3FTH1
• Organism: Lactiplantibacillus plantarum WCFS1
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 371436..383586

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LP_RS01740 (lp_0416)	-	371861..373033 (+)	1173	WP_223843867.1	sensor histidine kinase	-
LP_RS01745 (lp_0417)	-	373034..373777 (+)	744	WP_011100999.1	LytTR family transcriptional regulator DNA-binding domain-containing protein	-
LP_RS01750 (lp_0418)	-	373896..374639 (+)	744	WP_003641982.1	response regulator transcription factor	-
LP_RS01755 (lp_0419)	-	374944..375717 (-)	774	WP_003646470.1	CPBP family intramembrane glutamic endopeptidase	-
LP_RS01760 (lp_0421)	plnF	375816..375974 (-)	159	WP_003643811.1	two-peptide bacteriocin plantaricin EF subunit PlnF	-
LP_RS01765 (lp_0422)	plnE	375999..376169 (-)	171	WP_003641985.1	two-peptide bacteriocin plantaricin EF subunit PlnE	-
LP_RS01770 (lp_0423)	comA	376436..378586 (+)	2151	WP_003641986.1	peptide cleavage/export ABC transporter	Regulator
LP_RS01775 (lp_0424)	-	378602..379978 (+)	1377	WP_003641987.1	HlyD family secretion protein	-
LP_RS01780 (lp_0424a)	-	380213..380758 (+)	546	WP_003641989.1	CPBP family intramembrane glutamic endopeptidase	-
LP_RS01785 (lp_0426)	-	380825..381493 (+)	669	WP_003641990.1	CPBP family intramembrane glutamic endopeptidase	-
LP_RS01790 (lp_0428)	-	381580..382260 (+)	681	WP_003641991.1	CPBP family intramembrane glutamic endopeptidase	-
LP_RS01795 (lp_0429)	-	382354..383040 (+)	687	WP_011101000.1	CPBP family intramembrane glutamic endopeptidase	-
LP_RS01800 (lp_0430)	-	383156..383443 (+)	288	WP_063722041.1	type II toxin-antitoxin system RelE/ParE family toxin	-

Sequence

Protein

• Length: 716 a.a.
• Molecular weight: 79952.66 Da
• Isoelectric Point: 6.6531

>NTDB_id=22684 LP_RS01770 WP_003641986.1 376436..378586(+) (comA) [Lactiplantibacillus plantarum WCFS1]
MHWRNYVAQVDEMDCGVAALAMILKNYGSTTSLAYLRNIAKTSLEGTTALGLVKTAEKLGFETKAIQADMSLFEVQDLPL
PFIVHVTKNGDLQHFYVVVKTSKTHVVIADPDPTVAVISMSKERFESEWSGVALFFAPKSEYKPVKQDKGSLWGFIPSLL
KQRRLVINIVLAAVLITIISICGSYFLQAVIDTYIPNNMHSTLAVVAIGLIVFYTFQAIFTYAQNFLLAVLGQRLSIEII
LGYIRHVFELPMSFFATRRTGEIVSRFTDASKIIDALASTIVSLFLDVSIVIIMGAILVIQNMTLFWITLLSLPIYAVVI
LAFNKSFERLNQKEMESNAILSSAIIEDLHGIETVKALNGETERYQKIDSEFVDYLRKSLAYLKADTLQQALKLFIQLVL
EVVVLWVGANLVIHNQLSVGELMTYNALLAYFVNPLQNIINLQTKLQSAKVANNRLNEVYLVASEFEASRPIHNESQLNG
DIKLQGVSYRYGYGENVLDDVNLTIRQHDKVAIVGMSGSGKSTLVKLLIDFYQPNSGDVILNGFNVKNIDKHTLRTHINY
IPQEPYIFSATIEENLRLGNRSGITEKDIAKACQLALIDTDINKMAMQYQTKLDENGNTLSGGQRQRLTIARALLSPAQV
LIFDESTSGLDAITEKQLIDNLVAMTDKTIIFIAHRLSIAKRTNHIIVLHDGRVAEEGTHAALLNEHGYYYDLINS

Nucleotide

• Length: 2151 bp

>NTDB_id=22684 LP_RS01770 WP_003641986.1 376436..378586(+) (comA) [Lactiplantibacillus plantarum WCFS1]
ATGCATTGGAGAAACTATGTTGCGCAAGTTGACGAGATGGACTGTGGGGTCGCAGCTTTAGCAATGATTTTGAAAAATTA
TGGTTCGACAACATCATTGGCCTATCTAAGAAATATTGCTAAAACGAGTTTAGAAGGGACTACGGCATTAGGATTAGTAA
AAACGGCCGAAAAGTTAGGTTTTGAAACCAAAGCAATTCAAGCAGATATGAGTCTTTTCGAGGTACAAGATTTACCATTG
CCATTCATTGTGCATGTTACCAAAAATGGGGATCTACAGCATTTTTATGTCGTTGTAAAAACCTCGAAAACGCATGTCGT
GATTGCTGATCCGGACCCAACAGTTGCGGTTATCAGTATGTCAAAGGAACGGTTTGAAAGCGAATGGTCCGGAGTTGCCC
TTTTCTTTGCACCGAAGTCGGAATATAAGCCAGTTAAGCAAGATAAGGGCTCACTATGGGGATTTATTCCAAGCTTATTA
AAGCAGCGCCGACTGGTTATTAATATTGTGCTTGCTGCAGTTTTAATCACGATTATTAGTATCTGTGGGTCTTATTTCTT
ACAAGCGGTGATTGATACTTATATTCCCAATAATATGCACAGTACATTGGCAGTGGTGGCCATTGGTCTAATCGTTTTTT
ATACCTTTCAGGCTATCTTTACTTATGCCCAGAATTTTTTATTGGCGGTTTTAGGTCAACGACTTTCGATTGAAATTATT
TTAGGCTATATTCGGCACGTCTTTGAATTGCCAATGAGTTTTTTTGCCACTCGGCGGACGGGGGAAATTGTTTCGAGGTT
TACGGATGCCAGTAAGATTATTGATGCGTTAGCTAGCACAATTGTTTCGCTGTTTTTAGATGTCAGCATCGTTATTATTA
TGGGGGCAATCTTGGTAATCCAGAATATGACACTTTTTTGGATTACGTTACTCTCGTTGCCAATCTACGCGGTTGTCATC
TTAGCCTTTAATAAATCCTTTGAACGATTGAATCAAAAGGAAATGGAGAGCAATGCTATTTTGAGTTCAGCCATTATTGA
GGATCTTCATGGGATTGAAACTGTTAAGGCGCTGAATGGTGAGACGGAACGTTATCAGAAAATTGATTCAGAATTTGTTG
ATTATCTACGTAAGAGTTTAGCCTATCTTAAAGCGGATACTTTGCAACAGGCATTAAAACTGTTTATACAGTTAGTCTTA
GAAGTTGTTGTTCTATGGGTGGGCGCCAATCTCGTCATTCATAATCAGTTATCAGTTGGGGAGCTCATGACATATAATGC
TTTATTAGCCTATTTTGTTAATCCACTACAGAATATTATTAATTTGCAGACTAAGCTTCAAAGCGCTAAGGTCGCTAACA
ACCGGTTAAATGAAGTGTATTTGGTCGCTAGTGAATTTGAGGCGTCACGGCCAATTCATAATGAAAGTCAATTAAATGGT
GATATTAAGTTACAAGGGGTCAGCTATCGTTATGGTTACGGTGAAAATGTCTTAGATGATGTTAATTTGACGATTCGACA
ACATGATAAGGTTGCAATTGTGGGGATGAGTGGCTCTGGCAAGTCCACGTTAGTTAAATTGCTTATTGATTTTTATCAAC
CAAATAGTGGTGATGTCATATTGAATGGCTTCAACGTTAAGAACATCGATAAGCATACATTGCGGACCCATATTAACTAC
ATCCCGCAGGAACCATACATCTTTTCAGCGACCATTGAAGAAAATTTAAGATTAGGTAATCGCAGCGGTATTACTGAGAA
AGATATTGCGAAGGCTTGCCAATTGGCGTTAATTGATACGGATATTAATAAAATGGCCATGCAATACCAAACTAAGCTAG
ATGAGAATGGTAATACACTATCAGGTGGTCAGCGACAACGATTAACGATTGCGAGAGCGTTATTATCACCCGCTCAAGTC
TTGATATTTGATGAGTCGACGAGTGGACTGGATGCAATTACTGAAAAACAATTAATTGATAATTTAGTGGCAATGACTGA
CAAGACGATTATTTTTATTGCCCACCGGTTGTCGATTGCAAAGCGGACGAATCATATCATCGTTCTGCATGATGGTCGGG
TCGCTGAAGAGGGGACCCATGCGGCATTGTTGAATGAACATGGTTACTATTACGACTTGATCAATAGCTGA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (5-140)

• ABC transporter transmembrane region (ABC_membrane) (166-436)

• ABC transporter (ABC_tran) (498-648)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	58.906	99.581	0.587
comA	Streptococcus pneumoniae D39	58.626	99.581	0.584
comA	Streptococcus pneumoniae R6	58.626	99.581	0.584
comA	Streptococcus pneumoniae Rx1	58.626	99.581	0.584
comA	Streptococcus pneumoniae TIGR4	58.485	99.581	0.582
comA	Streptococcus mitis SK321	58.345	99.581	0.581
comA	Streptococcus gordonii str. Challis substr. CH1	57.103	100	0.573
comA/nlmT	Streptococcus mutans UA159	54.596	100	0.547