Detailed information NTG0226630

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: B9H01_RS08100
• Genome accession: NZ_CP020863
• Coordinates: 1595425..1596474 (-)
• Length: 349 a.a.
• NCBI ID: WP_012775295.1
• Uniprot ID: A0A2K1T047
• Organism: Streptococcus suis strain SC19
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1590425..1601474

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
B9H01_RS08080 (B9H01_08080)	nadE	1590831..1591655 (+)	825	WP_004194617.1	ammonia-dependent NAD(+) synthetase	-
B9H01_RS08085 (B9H01_08085)	-	1592951..1593478 (-)	528	WP_012027591.1	VanZ family protein	-
B9H01_RS08090 (B9H01_08090)	rlmN	1593475..1594587 (-)	1113	WP_012028433.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
B9H01_RS08095 (B9H01_08095)	-	1594596..1595237 (-)	642	WP_012027595.1	YutD-like domain-containing protein	-
B9H01_RS08100 (B9H01_08100)	sepM	1595425..1596474 (-)	1050	WP_012775295.1	SepM family pheromone-processing serine protease	Regulator
B9H01_RS08105 (B9H01_08105)	coaD	1596461..1596949 (-)	489	WP_012027597.1	pantetheine-phosphate adenylyltransferase	-
B9H01_RS08110 (B9H01_08110)	rsmD	1596939..1597478 (-)	540	WP_009910569.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
B9H01_RS08115 (B9H01_08115)	-	1597786..1598508 (-)	723	WP_012027598.1	lipoprotein	-
B9H01_RS08120 (B9H01_08120)	-	1598565..1598951 (-)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
B9H01_RS08125 (B9H01_08125)	-	1598951..1599169 (-)	219	WP_004194736.1	YqgQ family protein	-
B9H01_RS08130 (B9H01_08130)	-	1599477..1600079 (-)	603	WP_012027601.1	response regulator transcription factor	-
B9H01_RS08135 (B9H01_08135)	-	1600076..1601170 (-)	1095	WP_012027602.1	sensor histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37761.83 Da
• Isoelectric Point: 4.6112

>NTDB_id=226630 B9H01_RS08100 WP_012775295.1 1595425..1596474(-) (sepM) [Streptococcus suis strain SC19]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSIPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=226630 B9H01_RS08100 WP_012775295.1 1595425..1596474(-) (sepM) [Streptococcus suis strain SC19]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATCTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAGGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAGACATCGCAAAATATGGCGAAGTACCAAGGTTTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTGTCTAATGGCAAAAACGGGATAGGTATCACTCTCGTAG
ATCATACAGAGGTTCAAAGTTCGATTCCGATTGATTTCCAAACAGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGGATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTCATTTCGGCAGCTAAGTCTGGTGCAAGTATCTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAATCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACAAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A2K1T047

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.807	99.427	0.605