Detailed information    

insolico Bioinformatically predicted

Overview

Name   treR   Type   Regulator
Locus tag   SPYM18_RS09235 Genome accession   NC_003485
Coordinates   1811039..1811752 (+) Length   237 a.a.
NCBI ID   WP_002992823.1    Uniprot ID   A0A0H2UWR7
Organism   Streptococcus pyogenes MGAS8232     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1806039..1816752
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPYM18_RS09225 (spyM18_2154) treC 1807108..1808736 (-) 1629 WP_011018305.1 alpha,alpha-phosphotrehalase -
  SPYM18_RS09230 (spyM18_2155) treP 1808804..1810828 (-) 2025 WP_011018306.1 PTS system trehalose-specific EIIBC component -
  SPYM18_RS09235 (spyM18_2157) treR 1811039..1811752 (+) 714 WP_002992823.1 trehalose operon repressor Regulator
  SPYM18_RS09240 (spyM18_2160) - 1812031..1812369 (-) 339 WP_011018307.1 winged helix-turn-helix transcriptional regulator -
  SPYM18_RS09245 - 1812555..1813412 (+) 858 Protein_1801 VOC family protein -
  SPYM18_RS09250 (spyM18_2163) yaaA 1813454..1814185 (+) 732 WP_011018309.1 peroxide stress protein YaaA -
  SPYM18_RS09255 (spyM18_2164) nrdG 1814359..1814973 (-) 615 WP_011018310.1 anaerobic ribonucleoside-triphosphate reductase activating protein -
  SPYM18_RS09260 (spyM18_2165) - 1814973..1815482 (-) 510 WP_011018311.1 GNAT family N-acetyltransferase -
  SPYM18_RS09265 (spyM18_2166) - 1815491..1816426 (-) 936 WP_011018312.1 Gfo/Idh/MocA family protein -
  SPYM18_RS10415 (spyM18_2167) - 1816455..1816601 (-) 147 WP_002982210.1 hypothetical protein -

Sequence

Protein


Download         Length: 237 a.a.        Molecular weight: 27620.79 Da        Isoelectric Point: 9.6307

>NTDB_id=22616 SPYM18_RS09235 WP_002992823.1 1811039..1811752(+) (treR) [Streptococcus pyogenes MGAS8232]
MTKYERIYKDLETKINKDFYKEGDFLPTEIELSQQYQASRDTVRKALSLLTKAGLILKKQGRGTQVIRHHQIMFPISELT
SYQELVSYSNLDSKTNVIAIDKLIVDETLSKLTGFSKNSLVWRVTRQRVVEGVASVLDIDYLSKTLVPIMTREIAEHSIY
QYLEKELHLAIDFALKEVTIDQITDRDKILLDLGSDQHVVSVKSKVYLSNNNQFQFTESRHKLEKFKFLDFARRRPK

Nucleotide


Download         Length: 714 bp        

>NTDB_id=22616 SPYM18_RS09235 WP_002992823.1 1811039..1811752(+) (treR) [Streptococcus pyogenes MGAS8232]
ATGACAAAGTATGAACGTATTTATAAAGACCTCGAAACAAAAATAAACAAAGACTTTTACAAAGAAGGGGATTTTTTACC
TACTGAAATAGAATTGAGTCAACAATACCAAGCTAGCCGAGATACCGTCCGCAAGGCTCTCTCACTTCTCACAAAGGCAG
GTCTTATCCTCAAAAAACAAGGACGTGGCACCCAAGTGATTAGACATCATCAGATCATGTTCCCTATCTCAGAACTAACT
AGTTATCAGGAACTCGTCTCTTACTCAAATCTAGATTCTAAGACCAACGTCATTGCCATTGATAAACTGATTGTGGATGA
GACACTTTCAAAATTGACCGGTTTTAGCAAAAACAGCTTGGTCTGGCGTGTTACACGCCAACGCGTTGTTGAGGGTGTGG
CTTCCGTCTTAGACATTGATTACCTTAGTAAAACTTTGGTGCCAATAATGACAAGGGAAATCGCAGAGCATTCTATTTAT
CAATATTTGGAAAAGGAACTCCATCTCGCCATTGACTTTGCCCTCAAAGAGGTTACCATTGACCAAATAACCGATCGTGA
TAAAATTTTACTTGACCTTGGATCAGACCAACATGTTGTTTCCGTCAAATCCAAAGTCTACCTTTCCAATAATAACCAAT
TCCAATTCACCGAGAGTCGCCATAAACTGGAAAAATTTAAATTTTTAGATTTTGCTCGGCGCAGACCAAAATAA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, gntR family (GntR)

(3-66)

UTRA domain (UTRA)

(91-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UWR7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  treR Streptococcus mutans UA159

68.376

98.734

0.675