Detailed information    

insolico Bioinformatically predicted

Overview

Name   recP/tkt   Type   Machinery gene
Locus tag   SPYM18_RS07260 Genome accession   NC_003485
Coordinates   1403011..1404996 (-) Length   661 a.a.
NCBI ID   WP_011018079.1    Uniprot ID   -
Organism   Streptococcus pyogenes MGAS8232     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1398011..1409996
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPYM18_RS07235 (spyM18_1679) - 1398024..1399274 (-) 1251 WP_011018075.1 glutamate-5-semialdehyde dehydrogenase -
  SPYM18_RS07240 (spyM18_1681) proB 1399267..1400088 (-) 822 WP_011018076.1 glutamate 5-kinase -
  SPYM18_RS07245 (spyM18_1684) - 1400152..1401780 (-) 1629 WP_002988883.1 hypothetical protein -
  SPYM18_RS07250 (spyM18_1685) - 1401785..1402519 (-) 735 WP_011018078.1 ABC transporter ATP-binding protein -
  SPYM18_RS07255 (spyM18_1686) - 1402553..1402819 (-) 267 WP_002983572.1 bacteriocin immunity protein -
  SPYM18_RS07260 (spyM18_1687) recP/tkt 1403011..1404996 (-) 1986 WP_011018079.1 transketolase Machinery gene
  SPYM18_RS07265 (spyM18_1689) fsa 1405214..1405858 (-) 645 WP_002983569.1 fructose-6-phosphate aldolase -
  SPYM18_RS07270 (spyM18_1692) - 1405984..1407483 (-) 1500 WP_011018080.1 helix-turn-helix domain-containing protein -
  SPYM18_RS07275 (spyM18_1693) - 1407473..1408819 (-) 1347 WP_011018081.1 NAD(P)/FAD-dependent oxidoreductase -
  SPYM18_RS07280 (spyM18_1694) - 1408928..1409629 (-) 702 WP_011018082.1 MIP/aquaporin family protein -

Sequence

Protein


Download         Length: 661 a.a.        Molecular weight: 71333.11 Da        Isoelectric Point: 4.6481

>NTDB_id=22599 SPYM18_RS07260 WP_011018079.1 1403011..1404996(-) (recP/tkt) [Streptococcus pyogenes MGAS8232]
MTFDAIDQLAVNTVRTLSMDAIQAANSGHPGLPMGAAPMAYVLWNHFMNINPKTSRNWSNRDRFILSAGHGSAMLYSLLH
LAGYDLSVEDLKNFRQWGSKTPGHPEVNHTDGVEATTGPLGQGIANAVGMAMAEAHLAAKFNKPGFDIVDHYTFALNGDG
DLMEGVSQEAASMAGHLKLGKLVLLYDSNDISLDGPTSMAFTEDVKGRFEAYGWQHILVKDGNDLEEIAAAIEAAKAETE
KPTIIEVKTIIGFGAEKQGTSAVHGAPLGAEGIAFAKKAYQWTHQDFEVPAEVTERFAQGLQARGEKAEQAWNDLFAAYQ
AEYPELAAEYQKAFANEAAQVELEAHELGSSMASRVSSQQAIQQISEQVASFWGGSADLSASNNTMVKAETDFQPGHYEG
RNIWFGVREFAMAAAMNGIALHGGTRVYGGTFFVFSNYLLPAVRMAALQNLPTVYVMTHDSIAVGEDGPTHEPIEQLASV
RSMPNLNVIRPADGNETNAAWKRAIAETDRPTMLVLTRQNLPVLEGTKELAEDGLNKGAYILSEAKGDLDGIIIATGSEV
KLAMDTQEALEAEGIHVRVVSMPSQNIFDEQSAEYKESILPAAVTKRLAIEAGSSFGWAKYVGLAGKTLTIDTWGASAPG
NRIFEEYGFTVANATELYKSL

Nucleotide


Download         Length: 1986 bp        

>NTDB_id=22599 SPYM18_RS07260 WP_011018079.1 1403011..1404996(-) (recP/tkt) [Streptococcus pyogenes MGAS8232]
ATGACATTTGATGCAATTGACCAATTGGCAGTAAACACTGTCCGCACCCTATCAATGGATGCCATTCAAGCGGCAAATTC
TGGACACCCAGGACTTCCAATGGGGGCAGCACCTATGGCCTATGTTCTTTGGAATCACTTCATGAACATCAATCCCAAAA
CAAGCCGTAATTGGTCAAACAGAGACCGTTTTATCCTATCAGCAGGTCATGGAAGTGCCATGCTTTATAGCTTGTTGCAT
TTAGCAGGTTATGATTTATCTGTAGAAGATTTAAAGAACTTCCGTCAATGGGGATCTAAAACACCAGGTCACCCAGAAGT
GAACCACACAGACGGTGTCGAAGCAACCACAGGACCTCTTGGTCAAGGGATCGCAAATGCCGTTGGTATGGCCATGGCAG
AAGCTCACCTAGCAGCTAAATTTAACAAACCAGGCTTTGACATCGTTGATCACTACACATTTGCTTTGAATGGTGACGGT
GACCTTATGGAAGGGGTCAGCCAAGAAGCAGCAAGTATGGCAGGACATTTAAAACTTGGGAAATTGGTCTTGCTATATGA
TTCAAACGACATCTCTCTTGATGGTCCAACCTCTATGGCTTTCACAGAAGATGTGAAAGGACGTTTCGAAGCTTATGGTT
GGCAACATATCCTTGTGAAAGATGGAAATGATTTAGAAGAAATTGCAGCTGCTATTGAAGCAGCTAAAGCTGAAACTGAG
AAACCAACCATCATCGAAGTCAAAACCATTATTGGTTTTGGTGCCGAAAAACAAGGAACTTCAGCTGTTCACGGCGCTCC
TCTTGGAGCAGAAGGCATTGCTTTTGCCAAAAAAGCTTACCAATGGACTCATCAAGATTTTGAAGTACCTGCTGAAGTGA
CTGAACGTTTTGCTCAAGGACTTCAAGCACGTGGTGAAAAAGCAGAACAAGCCTGGAATGACTTGTTTGCAGCTTATCAA
GCAGAATATCCTGAATTGGCAGCAGAATACCAAAAAGCCTTTGCTAACGAAGCTGCTCAAGTTGAACTTGAAGCGCACGA
ACTTGGCAGCTCAATGGCGAGTCGTGTTTCTAGCCAACAAGCCATCCAACAAATCTCAGAACAAGTAGCCTCTTTCTGGG
GTGGATCAGCAGATCTTTCAGCATCTAACAACACAATGGTTAAGGCTGAAACAGATTTCCAACCAGGTCACTACGAAGGC
CGTAACATCTGGTTTGGCGTTCGTGAATTTGCCATGGCTGCAGCCATGAACGGTATTGCCCTTCACGGCGGGACACGCGT
TTACGGCGGAACCTTCTTTGTCTTCTCAAACTATCTTCTTCCAGCTGTTCGTATGGCAGCGCTCCAAAACTTGCCAACAG
TTTATGTCATGACACATGATTCTATCGCTGTTGGTGAAGATGGGCCAACGCACGAACCAATTGAACAATTGGCAAGTGTT
CGTTCAATGCCTAACTTGAACGTTATTCGTCCAGCAGACGGTAACGAAACAAATGCTGCTTGGAAACGTGCCATTGCTGA
AACAGATCGCCCAACCATGCTTGTATTGACGCGTCAAAACCTTCCAGTGCTTGAGGGAACAAAAGAATTGGCAGAAGATG
GTCTTAACAAAGGAGCTTACATTTTATCAGAAGCCAAAGGCGACCTTGATGGTATCATCATTGCAACAGGTTCAGAAGTG
AAACTGGCAATGGATACTCAAGAAGCTCTTGAAGCAGAAGGCATTCATGTGCGTGTGGTATCTATGCCATCACAAAATAT
CTTTGACGAACAGTCAGCAGAGTATAAAGAAAGCATCCTACCAGCAGCTGTGACTAAACGTCTCGCTATCGAAGCAGGTT
CAAGCTTTGGCTGGGCAAAATATGTCGGCCTAGCAGGAAAAACATTGACCATTGACACTTGGGGTGCTTCAGCTCCAGGA
AATCGTATCTTCGAAGAATATGGTTTCACTGTGGCAAATGCAACTGAGTTATACAAATCACTCTAG

Domains

Predicted by InterProScan.

Transketolase, C-terminal domain (Transketolase_C)

(552-652)

Transketolase, thiamine diphosphate binding domain (Transketolase_N)

(6-336)

Transketolase, pyrimidine binding domain (Transket_pyr)

(352-522)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  recP/tkt Streptococcus pneumoniae TIGR4

55.775

99.546

0.555

Multiple sequence alignment