Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   B7941_RS08450 Genome accession   NZ_CP020805
Coordinates   1642186..1642842 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain 9D-6     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1637186..1647842
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  B7941_RS08425 (B7941_08415) oppF 1637715..1638632 (+) 918 WP_020955632.1 oligopeptide ABC transporter ATP-binding protein OppF -
  B7941_RS08430 (B7941_08420) - 1638739..1639926 (+) 1188 WP_020955633.1 putative glycoside hydrolase -
  B7941_RS08435 (B7941_08425) - 1640044..1640622 (+) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  B7941_RS08440 (B7941_08430) spx 1640801..1641196 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  B7941_RS08445 (B7941_08435) - 1641254..1641910 (-) 657 WP_007409109.1 TerC family protein -
  B7941_RS19980 - 1642093..1642203 (+) 111 Protein_1621 adaptor protein MecA -
  B7941_RS08450 (B7941_08440) mecA 1642186..1642842 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  B7941_RS08455 (B7941_08445) - 1642993..1644153 (+) 1161 WP_085341883.1 competence protein CoiA family protein -
  B7941_RS08460 (B7941_08450) pepF 1644381..1646210 (+) 1830 WP_007409107.1 oligoendopeptidase F Regulator
  B7941_RS19985 - 1646248..1646415 (-) 168 WP_003155026.1 hypothetical protein -
  B7941_RS08465 (B7941_08455) spxH 1646701..1647603 (-) 903 WP_003155024.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=225943 B7941_RS08450 WP_003155032.1 1642186..1642842(+) (mecA) [Bacillus velezensis strain 9D-6]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=225943 B7941_RS08450 WP_003155032.1 1642186..1642842(+) (mecA) [Bacillus velezensis strain 9D-6]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895

Multiple sequence alignment