Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   SPYM18_RS04305 Genome accession   NC_003485
Coordinates   819768..820244 (+) Length   158 a.a.
NCBI ID   WP_011017701.1    Uniprot ID   -
Organism   Streptococcus pyogenes MGAS8232     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 814768..825244
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPYM18_RS04280 (spyM18_0988) - 814809..815597 (+) 789 WP_002984887.1 Nif3-like dinuclear metal center hexameric protein -
  SPYM18_RS04285 (spyM18_0989) - 815637..816743 (+) 1107 WP_011017700.1 NAD(P)/FAD-dependent oxidoreductase -
  SPYM18_RS04290 (spyM18_0990) rfbA 816801..817670 (+) 870 WP_002992970.1 glucose-1-phosphate thymidylyltransferase RfbA -
  SPYM18_RS04295 (spyM18_0992) - 817670..818263 (+) 594 WP_002990099.1 dTDP-4-dehydrorhamnose 3,5-epimerase family protein -
  SPYM18_RS04300 (spyM18_0993) rfbB 818507..819547 (+) 1041 WP_002984881.1 dTDP-glucose 4,6-dehydratase -
  SPYM18_RS04305 (spyM18_0994) mutX 819768..820244 (+) 477 WP_011017701.1 NUDIX hydrolase Machinery gene
  SPYM18_RS04310 (spyM18_0995) - 820302..821483 (+) 1182 WP_011017702.1 AI-2E family transporter -
  SPYM18_RS04315 (spyM18_0996) - 821473..822720 (+) 1248 WP_002984878.1 tetratricopeptide repeat protein -
  SPYM18_RS04320 (spyM18_0997) fbp54 822779..824431 (-) 1653 WP_011017703.1 Rqc2 family fibronectin-binding protein Fbp54 -

Sequence

Protein


Download         Length: 158 a.a.        Molecular weight: 18474.74 Da        Isoelectric Point: 4.3268

>NTDB_id=22573 SPYM18_RS04305 WP_011017701.1 819768..820244(+) (mutX) [Streptococcus pyogenes MGAS8232]
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECARREILEETHLTVIEMAFKGIITFPEFTPGH
DWYTYVFKVTGFEGDLISDEESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY

Nucleotide


Download         Length: 477 bp        

>NTDB_id=22573 SPYM18_RS04305 WP_011017701.1 819768..820244(+) (mutX) [Streptococcus pyogenes MGAS8232]
ATGACTCAATTAGCAACCATTTGTTACATTGATAATGGCGATTCTTTGCTATTATTACACCGCAATAAAAAAGAAAATGA
TGTCCACAAAGGCAAGTGGATTTCAGTTGGGGGTAAGCTCGAGGCTGGTGAGACCCCAGATGAGTGTGCCCGTCGTGAGA
TTTTAGAGGAAACCCATTTGACTGTTATAGAGATGGCCTTTAAAGGAATCATTACTTTTCCAGAATTTACCCCTGGTCAT
GACTGGTATACCTATGTTTTTAAAGTAACAGGATTTGAAGGAGACCTCATTTCAGATGAAGAGTCACGAGAAGGAACCTT
GGAATGGGTACCTTACGATCAAGTGTTGGAAAAGCCAACTTGGGAAGGTGATTATGACATTTTTAAATGGATTTTAGAAG
ACCGTCCTTTTTTCTCTGCCAAATTTACCTATGACCAAAACAACCAACTCATGGATAAATCTGTGACCTTTTATTGA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

70.253

100

0.703

Multiple sequence alignment