Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   B7437_RS08285 Genome accession   NZ_CP020741
Coordinates   1651682..1652656 (-) Length   324 a.a.
NCBI ID   WP_000697218.1    Uniprot ID   -
Organism   Staphylococcus aureus strain HZW450     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1646682..1657656
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  B7437_RS08245 (B7437_08315) gcvT 1647183..1648274 (-) 1092 WP_000093349.1 glycine cleavage system aminomethyltransferase GcvT -
  B7437_RS08250 (B7437_08320) - 1648433..1648957 (-) 525 WP_001015116.1 shikimate kinase -
  B7437_RS08255 (B7437_08325) - 1648947..1649093 (-) 147 WP_001789879.1 hypothetical protein -
  B7437_RS08260 (B7437_08330) comGF 1649190..1649687 (-) 498 WP_001838632.1 competence type IV pilus minor pilin ComGF Machinery gene
  B7437_RS08265 (B7437_08335) comGE 1649605..1649904 (-) 300 WP_000844413.1 hypothetical protein Machinery gene
  B7437_RS08270 (B7437_08340) comGD 1649891..1650337 (-) 447 WP_001796473.1 competence type IV pilus minor pilin ComGD Machinery gene
  B7437_RS08275 (B7437_08345) comGC 1650315..1650626 (-) 312 WP_000472256.1 competence type IV pilus major pilin ComGC Machinery gene
  B7437_RS08280 (B7437_08350) comGB 1650640..1651710 (-) 1071 WP_000776407.1 competence type IV pilus assembly protein ComGB Machinery gene
  B7437_RS08285 (B7437_08355) comGA 1651682..1652656 (-) 975 WP_000697218.1 competence type IV pilus ATPase ComGA Machinery gene
  B7437_RS08290 (B7437_08360) - 1652708..1653331 (-) 624 WP_001223008.1 MBL fold metallo-hydrolase -
  B7437_RS08295 (B7437_08365) - 1653328..1653657 (-) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  B7437_RS08300 (B7437_08370) - 1653657..1654643 (-) 987 WP_000161315.1 ROK family glucokinase -
  B7437_RS08305 (B7437_08375) - 1654640..1654843 (-) 204 WP_000087561.1 YqgQ family protein -
  B7437_RS08310 (B7437_08380) - 1654824..1656287 (-) 1464 WP_001017869.1 rhomboid family protein -
  B7437_RS08315 (B7437_08385) - 1656299..1656838 (-) 540 WP_000164548.1 5-formyltetrahydrofolate cyclo-ligase -
  B7437_RS08320 (B7437_08390) rpmG 1657047..1657196 (-) 150 WP_001265709.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 324 a.a.        Molecular weight: 36970.02 Da        Isoelectric Point: 8.6529

>NTDB_id=225633 B7437_RS08285 WP_000697218.1 1651682..1652656(-) (comGA) [Staphylococcus aureus strain HZW450]
MKILFQEIINKAIEMKASDVHFIPVKNEVSIKFRINDNLEQYEQIGNSIYQKLLVYMKFQAGLDVSTQQVAQSGRYSYHF
NKIYFLRISTLPLSLGQESCVIRIVPQFFQQQKSTYKFNDFKHLMNKKQELLLFSGPTGSGKSTLMYQMVSYANKALNLN
VISIEDPVEMQIPGIVQINVNDKAGINYVNSFKAILRCDPDVILIGEIRDKDVAKCVIQASLSGHLVLTTLHATDCKGAI
LRLLEMGISVQELIQATNLIINQRLVTTIKQQRQLVCEILSQQQLRYFFSHNHSLPSSFKNLEDKLDDMTKAGVICETTM
DKYI

Nucleotide


Download         Length: 975 bp        

>NTDB_id=225633 B7437_RS08285 WP_000697218.1 1651682..1652656(-) (comGA) [Staphylococcus aureus strain HZW450]
TTGAAGATTCTATTTCAAGAAATAATTAATAAAGCGATAGAAATGAAAGCGAGTGATGTACATTTTATTCCAGTTAAAAA
TGAAGTAAGTATTAAATTTAGAATTAATGATAACTTGGAGCAGTATGAACAAATTGGGAATAGCATTTATCAAAAGTTAT
TAGTTTATATGAAGTTTCAAGCTGGGCTTGATGTTTCTACACAGCAAGTCGCACAGAGCGGTCGATATAGTTACCATTTC
AATAAAATATATTTTTTGAGAATATCAACTTTACCATTGTCACTTGGCCAAGAAAGTTGTGTTATCAGAATTGTACCTCA
ATTTTTTCAACAACAGAAATCAACTTATAAATTCAATGATTTTAAACACCTCATGAATAAGAAACAAGAATTACTATTGT
TTAGTGGGCCAACTGGTTCAGGAAAGAGTACATTAATGTATCAAATGGTCTCATACGCGAATAAAGCCCTGAATTTAAAT
GTAATTTCTATAGAGGATCCTGTAGAGATGCAAATTCCTGGTATCGTCCAAATTAATGTGAATGATAAAGCTGGCATTAA
CTATGTAAATTCGTTTAAAGCTATTTTAAGATGTGATCCTGATGTAATTTTAATAGGTGAAATCAGAGATAAAGATGTTG
CCAAGTGTGTTATACAGGCTAGTTTAAGTGGTCACCTTGTTCTGACTACATTGCATGCAACTGATTGTAAGGGTGCTATT
TTAAGGCTATTAGAAATGGGCATTTCTGTACAAGAATTGATACAGGCAACTAACTTAATTATAAACCAACGACTTGTAAC
TACTATTAAGCAACAGCGACAATTAGTATGTGAAATTCTATCTCAGCAACAACTCCGATATTTCTTTTCCCATAATCATT
CATTACCATCATCATTTAAGAACTTAGAAGATAAACTTGATGATATGACAAAAGCAGGTGTCATTTGTGAAACTACAATG
GATAAATACATTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(7-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Staphylococcus aureus MW2

99.691

100

0.997
  comGA Staphylococcus aureus N315

99.691

100

0.997

Multiple sequence alignment