Detailed information NTG0225556

Bioinformatically predicted

Overview

• Name: spo0A
• Type: Regulator
• Locus tag: B7P25_RS21750
• Genome accession: NZ_CP020723
• Coordinates: 4016638..4017432 (-)
• Length: 264 a.a.
• NCBI ID: WP_003161566.1
• Uniprot ID: P52928
• Organism: Bacillus thuringiensis strain BM-BT15426
• Function: activation and repression of comK; repression of rok; repression of abrB (predicted from homology) Competence regulation

Genomic Context

Location: 4011638..4022432

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
B7P25_RS21730 (B7P25_21680)	-	4013440..4013673 (+)	234	WP_001190187.1	DUF2627 domain-containing protein	-
B7P25_RS21735 (B7P25_21685)	-	4013722..4014450 (-)	729	WP_000172561.1	glycerophosphodiester phosphodiesterase	-
B7P25_RS21740 (B7P25_21690)	-	4014501..4014647 (+)	147	WP_001247670.1	YycC family protein	-
B7P25_RS21745 (B7P25_21695)	-	4014815..4016340 (-)	1526	Protein_4046	hypothetical protein	-
B7P25_RS21750 (B7P25_21700)	spo0A	4016638..4017432 (-)	795	WP_003161566.1	sporulation transcription factor Spo0A	Regulator
B7P25_RS21760 (B7P25_21710)	spoIVB	4017720..4019018 (-)	1299	WP_002037056.1	SpoIVB peptidase	-
B7P25_RS21765 (B7P25_21715)	recN	4019137..4020876 (-)	1740	WP_000947757.1	DNA repair protein RecN	Machinery gene
B7P25_RS21770 (B7P25_21720)	argR	4021144..4021593 (-)	450	WP_001032581.1	arginine repressor ArgR	-

Sequence

Protein

• Length: 264 a.a.
• Molecular weight: 29440.17 Da
• Isoelectric Point: 7.4718

>NTDB_id=225556 B7P25_RS21750 WP_003161566.1 4016638..4017432(-) (spo0A) [Bacillus thuringiensis strain BM-BT15426]
MEKIKVCLVDDNKELVSMLESYVAAQDDMEVIGTAYNGQECLNLLKDKQPDVLVLDIIMPHLDGLAVLEKMRHIERLRQP
SVIMLTAFGQEDVTKKAVDLGASYFILKPFDMENLTSHIRQVSGKANATIKRPLPSFRSATTVDGKPKNLDASITSIIHE
IGVPAHIKGYMYLREAISMVYNDIELLGSITKVLYPDIAKKYNTTASRVERAIRHAIEVAWSRGNIDSISSLFGYTVSMS
KAKPTNSEFIAMVADKLRLEHKAS

Nucleotide

• Length: 795 bp

>NTDB_id=225556 B7P25_RS21750 WP_003161566.1 4016638..4017432(-) (spo0A) [Bacillus thuringiensis strain BM-BT15426]
GTGGAGAAAATTAAAGTATGTCTTGTGGATGATAATAAAGAATTAGTATCAATGCTAGAGAGTTATGTAGCTGCTCAAGA
TGATATGGAAGTAATCGGTACTGCTTATAATGGTCAAGAGTGTTTAAATTTATTAAAAGATAAGCAGCCGGATGTACTCG
TATTGGATATTATTATGCCACATTTAGATGGTTTAGCTGTACTAGAGAAAATGCGACATATTGAAAGGTTAAGACAGCCT
AGCGTAATTATGTTGACAGCATTTGGACAAGAAGATGTGACGAAAAAAGCAGTTGACTTAGGTGCTTCATATTTCATATT
AAAACCATTTGATATGGAAAATTTAACGAGTCATATTCGTCAAGTGAGCGGTAAGGCGAACGCTACTATTAAACGTCCAC
TGCCATCTTTCCGATCAGCAACAACAGTAGATGGAAAACCGAAAAATTTAGACGCGAGCATTACGAGTATCATTCATGAA
ATTGGTGTGCCTGCTCATATTAAAGGGTACATGTACTTAAGGGAAGCAATTTCTATGGTGTACAATGATATCGAATTACT
TGGATCTATTACGAAAGTATTGTATCCAGATATCGCGAAGAAATATAATACAACAGCAAGCCGCGTTGAGCGTGCAATCC
GTCACGCAATTGAAGTAGCATGGAGTCGTGGGAATATTGATTCTATTTCGTCCTTATTCGGTTATACAGTATCCATGTCA
AAAGCAAAACCTACGAACTCTGAGTTTATTGCAATGGTTGCGGATAAGTTGAGACTTGAACATAAGGCTAGCTGA

Domains

Predicted by InterproScan.

• Sporulation initiation factor Spo0A C terminal (Spo0A_C) (154-257)

• Response regulator receiver domain (Response_reg) (6-119)

3D structure

• AlphaFold DB: P52928

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
spo0A	Bacillus subtilis subsp. subtilis str. 168	80.899	100	0.818