Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   B7474_RS13260 Genome accession   NZ_CP020714
Coordinates   2532887..2533603 (+) Length   238 a.a.
NCBI ID   WP_064136995.1    Uniprot ID   -
Organism   Staphylococcus aureus strain K18     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2527887..2538603
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  B7474_RS13230 (B7474_13270) - 2528108..2528733 (+) 626 Protein_2494 nitroreductase family protein -
  B7474_RS13235 (B7474_13280) - 2529094..2529879 (+) 786 WP_101766725.1 carbon-nitrogen family hydrolase -
  B7474_RS14600 hld 2530476..2530556 (-) 81 WP_000046022.1 delta-hemolysin -
  B7474_RS13245 (B7474_13290) - 2530846..2531409 (+) 564 WP_001105696.1 accessory gene regulator AgrB -
  B7474_RS13250 (B7474_13295) agrD 2531412..2531555 (+) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  B7474_RS13255 (B7474_13300) agrC 2531585..2532868 (+) 1284 WP_000447888.1 quorum-sensing sensor histidine kinase AgrC -
  B7474_RS13260 (B7474_13305) agrA 2532887..2533603 (+) 717 WP_064136995.1 quorum-sensing response regulator AgrA Regulator
  B7474_RS13265 (B7474_13310) - 2533683..2533792 (+) 110 Protein_2501 hypothetical protein -
  B7474_RS13270 (B7474_13315) - 2533980..2534939 (-) 960 WP_001253314.1 carbohydrate kinase family protein -
  B7474_RS13275 (B7474_13320) - 2534936..2536420 (-) 1485 WP_000141414.1 sucrose-6-phosphate hydrolase -
  B7474_RS13280 (B7474_13325) - 2536569..2537519 (-) 951 WP_101766724.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27880.87 Da        Isoelectric Point: 5.8592

>NTDB_id=225517 B7474_RS13260 WP_064136995.1 2532887..2533603(+) (agrA) [Staphylococcus aureus strain K18]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDCFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=225517 B7474_RS13260 WP_064136995.1 2532887..2533603(+) (agrA) [Staphylococcus aureus strain K18]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATTGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTTAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.16

100

0.992

Multiple sequence alignment