Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   B7474_RS07415 Genome accession   NZ_CP020714
Coordinates   1465471..1466136 (-) Length   221 a.a.
NCBI ID   WP_000697877.1    Uniprot ID   A0A0D1JN68
Organism   Staphylococcus aureus strain K18     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1460471..1471136
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  B7474_RS07395 (B7474_07405) - 1461030..1461143 (-) 114 WP_072384844.1 hypothetical protein -
  B7474_RS07400 (B7474_07410) - 1461802..1463712 (-) 1911 WP_101766487.1 ABC transporter permease -
  B7474_RS07405 (B7474_07415) - 1463709..1464464 (-) 756 WP_000923760.1 ABC transporter ATP-binding protein -
  B7474_RS07410 (B7474_07420) braS 1464573..1465460 (-) 888 WP_000143426.1 nisin susceptibility-associated two-component system sensor histidine kinase NsaS Regulator
  B7474_RS07415 (B7474_07425) braR 1465471..1466136 (-) 666 WP_000697877.1 nisin susceptibility-associated two-component system response regulator NsaR Regulator
  B7474_RS07420 (B7474_07430) - 1466162..1466362 (-) 201 WP_000604727.1 hypothetical protein -
  B7474_RS07425 (B7474_07435) - 1466560..1467984 (+) 1425 WP_101766486.1 alkaline phosphatase -
  B7474_RS14560 (B7474_07440) - 1468043..1468144 (-) 102 WP_000731976.1 SE2200 family small protein -
  B7474_RS07435 (B7474_07445) - 1468266..1468721 (-) 456 WP_000106185.1 MarR family winged helix-turn-helix transcriptional regulator -
  B7474_RS07440 (B7474_07450) - 1468966..1469727 (-) 762 WP_000323441.1 alpha/beta hydrolase -
  B7474_RS07445 (B7474_07455) - 1469843..1470115 (-) 273 Protein_1419 LPXTG cell wall anchor domain-containing protein -
  B7474_RS07450 (B7474_07460) - 1470118..1470840 (+) 723 Protein_1420 hypothetical protein -
  B7474_RS07455 (B7474_07465) - 1470975..1471079 (+) 105 WP_001791758.1 hypothetical protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 25415.49 Da        Isoelectric Point: 4.7961

>NTDB_id=225502 B7474_RS07415 WP_000697877.1 1465471..1466136(-) (braR) [Staphylococcus aureus strain K18]
MKILIVEDDFVIAESLASELKKWNYGVIVVEQFDDILSIFNQHQPQLVLLDINLPTLNGFHWCQEIRKTSNVPIIFISSR
IDNMDQIMAIQMGGDDFIEKPFNLSLTIAKIQALLRRTYDLSVANDSLTVKGCTLILDEAKVVYQEQNIQLSLTELQILK
LLFQNEDKYVSRTALIEKCWESENFIDDNTLAVNMTRLRKKLNTIGVNDFIITKKNVGYKV

Nucleotide


Download         Length: 666 bp        

>NTDB_id=225502 B7474_RS07415 WP_000697877.1 1465471..1466136(-) (braR) [Staphylococcus aureus strain K18]
ATGAAAATATTAATTGTTGAAGATGATTTTGTTATAGCAGAAAGTTTAGCATCTGAACTTAAAAAATGGAATTACGGTGT
TATTGTCGTTGAACAATTTGATGATATACTGTCTATCTTTAACCAACATCAACCTCAGCTTGTATTGCTAGATATTAATT
TGCCAACGTTAAATGGTTTTCATTGGTGTCAAGAAATCCGAAAAACATCTAATGTGCCAATTATATTTATTAGTTCCCGT
ATTGATAATATGGACCAAATTATGGCAATACAAATGGGGGGAGATGATTTTATCGAAAAACCATTTAACTTGTCATTAAC
GATTGCCAAAATTCAAGCATTATTGAGACGAACTTATGACTTGTCAGTAGCTAATGATTCATTGACGGTTAAAGGTTGTA
CATTAATATTAGATGAAGCAAAAGTCGTGTATCAAGAACAAAACATACAGCTATCTTTGACTGAATTACAAATATTAAAG
TTATTATTTCAAAATGAAGATAAATATGTAAGTAGAACTGCTTTAATTGAAAAATGTTGGGAATCAGAAAACTTCATAGA
TGATAACACATTAGCTGTTAACATGACGCGCCTGCGTAAAAAATTAAATACTATTGGCGTTAATGATTTTATCATTACAA
AGAAAAATGTCGGATATAAAGTATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-111)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0D1JN68

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

100

100

1

Multiple sequence alignment